On August 31， 2025， the Asian Pacific Association for the Study of the Liver （APASL） updated and released management of acute variceal bleeding： updated APASL guidelines （2025 edition）， which systematically elaborates on the definition， diagnosis， assessment， and treatment of acute variceal bleeding. This article gives an excerpt of the recommendations in this guideline.

Nonalcoholic fatty liver disease (NAFLD) has become the leading cause of abnormal liver enzymes in healthy individuals in China. Due to the complex pathogenesis of NAFLD, no consensus has been reached on the treatment of this disease. However, in recent years, more and more studies have put forward more pathogeneses and corresponding treatment recommendations. This article introduces and summarizes the research advances in the treatment of NAFLD, including lifestyle intervention, drug treatment, eradication of Helicobacter pylori, surgical treatment, regulation of intestinal microecology, and gene therapy.