Humans ; Hypertension ; psychology ; Occupations ; Social Support

A 73-year-old woman with chronic bronchitis, pulmonary interstitial fibrosis, bronchiectasis concurrent infection received an IV infusion of levofloxacin 0. 4 g once daily. One week later, her symptoms were not improved. An IV infusion of tigecycline 50 mg twice daily was added to her regimen according to sputum culture results and drug sensitivity test. Nine days later,the patient developed nausea and vomiting. Laboratory tests showed serum urea value of 36. 5 mmol/ L and amylase 1 166 U/ L. Tigecycline was replaced by IV infusion of imipenem and cilastatin sodium 1. 0 g thrice daily,and levofloxacin continued. Octreotide acetate and pantoprazole sodium were given. Fasting and fluid supplement were applied. One week later,the nausea and vomiting disappeared. Her serum urea and amylase were 8. 1 mmol/ L and 42 U/ L,respectively.

A 73-year-old woman with chronic bronchitis, pulmonary interstitial fibrosis, bronchiectasis concurrent infection received an IV infusion of levofloxacin 0. 4 g once daily. One week later, her symptoms were not improved. An IV infusion of tigecycline 50 mg twice daily was added to her regimen according to sputum culture results and drug sensitivity test. Nine days later,the patient developed nausea and vomiting. Laboratory tests showed serum urea value of 36. 5 mmol/ L and amylase 1 166 U/ L. Tigecycline was replaced by IV infusion of imipenem and cilastatin sodium 1. 0 g thrice daily,and levofloxacin continued. Octreotide acetate and pantoprazole sodium were given. Fasting and fluid supplement were applied. One week later,the nausea and vomiting disappeared. Her serum urea and amylase were 8. 1 mmol/ L and 42 U/ L,respectively.

Acute Disease ; Adult ; Female ; Humans ; Male ; Middle Aged ; Phosphorus Compounds ; poisoning ; Retrospective Studies

Objective:To explore the relationship between the polymorphisms in gene FGFR1, FGF10, FGFI8 and the nonsyndromic cleft lip with or without cleft palate (NS CLP) in Chinese population. Methods: Genomic DNA was isolated from peripheral lymphocytes of 75 patients with NS CLP and their parents and 75 unimpaired healthy children. The polymorphisms in FGFRI gene rs13317, p. E467K, p. M3691 and p. S393S, FGF10 gene rs1448037 and FGFI8 gene rs4043716 were detected by applying three-dimensional (3-D) polyacrylamide gel microarray technology. The data were performed using statis-tical analysis : the genotype frequenc+ y and allele frequency between patients with NSCL/P and control subjects were performed. Haplotype relative risk (HRR) , family based association test (FBAT) , and transmission disequilibrium test (TDT) in nuclear family were performed. Results: There were no poly-morphism in FGFR1 gene p. E467K, p. M369I and p. $393S site, the corresponding base was all G. The polymorphisms of rs13317 and rs1448037 were detected and their genotype frequency and allele frequen-cy showed no significant difference between 75 patients with NSCL/P and 75 normal children. TDT, HRR and FBAT were also no significant differences. The genotype frequency of gene FGF18 rs4043716 showed significant difference, but allele frequency were no significant difference. TDT, HRR and FBAT were also no significant difference. Conclusion: Our studies suggest an association between gene FGF18 rs4043716 and the NS CLP in Chinese population, and no association among gene FGFR1 rs13317, p. FA67K, p. M3691, p. S393S and gene FGF10 rs1448037.