Objective:To explore the differences in the infertility stress, subjective well-being and fertility quality of life among infertile couples and mediating role of psychological resilience.Methods:A cross-sectional study and convenient sampling method were used to recruit the new diagnosed as infertility couples from April 2017 to April 2018 in the Reproductive Center of the First Affiliated Hospital of Zhengzhou University. The Resilience Scale (CD-RISC), the Fertility Problem Inventory (FPI), the Subjective Well-being Scale (SWBS) and the Fertility Quality of Life Questionnaire (FertiQoL) were used to investigate the 230 infertile couples.Results:Infertility couples had statistical differences in psychological resilience ( P=0.034), infertility stress ( P<0.001), and fertility quality of life ( P=0.005), and there was no statistically significant difference in subjective well-being. The fitting degree of structural equation model of infertility stress and subjective well-being and fertility quality of life among infertility women was relatively ideal [χ 2/ df=1.437, goodness of fit index (GIF)=0.936, adjusted goodness of fit index (AGFI)=0.909, root mean square error of approximation (RMSEA)=0.043], and the mediating effects of psychological resilience on subjective well-being and fertility quality of life was significant. The fitting degree of structural equation model of infertility stress and subjective well-being and fertility quality of life among infertility men was relatively ideal [χ 2/ df=2.011, GFI=0.93, incremental fit index (IFI)=0.918, comparative fit index (CFI)=0.917, RMSEA=0.067], and psychological resilience had a mediating effect on fertility quality of life, but had no mediating effect on subjective well-being. Conclusion:There are differences in infertility stress and fertility quality of life among infertile couples. psychological resilience has a mediating effect on the infertility stress and fertility quality of life among infertile couples.

Objective:To explore the relationship between salivary alpha-amylase (SAA) and infertility stress in infertile women.Methods:A convenient sampling method was used to investigate the infertile women in the Reproductive Medicine Center of the First Affiliated Hospital of Zhengzhou University from April 2017 to December 2017. A total of 458 infertile women were examined using the SAA and the Fertility Problem Inventory (FPI). SAA level was measured using an enzyme-linked immunosorbent assay (ELISA) kit.Results:The total infertility stress score was 155.86±24.54. The family monthly income, the cause of infertility and the type of infertility were statistically different between different groups ( t=4.123, P=0.041; F=4.079, P<0.001; t=4.491, P=0.035). Pearson correlation analysis showed that SAA and social concern, relationship concern, need for parenthood, rejection of child-free life, sexual concern and total infertility stress were significantly correlated ( r=0.360, r=0.348, r=0.222, r=0.166, r=0.203, r=0.426, all P<0.001). Multiple linear regression results showed that infertility stress, infertility causes and types of infertility were factors influencing SAA. Conclusion:SAA was associated with infertility stress. Combined with SAA and FPI may assess the psychological stress more objectively for infertile women.

Objective:To explore the differences in the infertility stress, subjective well-being and fertility quality of life among infertile couples and mediating role of psychological resilience.Methods:A cross-sectional study and convenient sampling method were used to recruit the new diagnosed as infertility couples from April 2017 to April 2018 in the Reproductive Center of the First Affiliated Hospital of Zhengzhou University. The Resilience Scale (CD-RISC), the Fertility Problem Inventory (FPI), the Subjective Well-being Scale (SWBS) and the Fertility Quality of Life Questionnaire (FertiQoL) were used to investigate the 230 infertile couples.Results:Infertility couples had statistical differences in psychological resilience ( P=0.034), infertility stress ( P<0.001), and fertility quality of life ( P=0.005), and there was no statistically significant difference in subjective well-being. The fitting degree of structural equation model of infertility stress and subjective well-being and fertility quality of life among infertility women was relatively ideal [χ 2/ df=1.437, goodness of fit index (GIF)=0.936, adjusted goodness of fit index (AGFI)=0.909, root mean square error of approximation (RMSEA)=0.043], and the mediating effects of psychological resilience on subjective well-being and fertility quality of life was significant. The fitting degree of structural equation model of infertility stress and subjective well-being and fertility quality of life among infertility men was relatively ideal [χ 2/ df=2.011, GFI=0.93, incremental fit index (IFI)=0.918, comparative fit index (CFI)=0.917, RMSEA=0.067], and psychological resilience had a mediating effect on fertility quality of life, but had no mediating effect on subjective well-being. Conclusion:There are differences in infertility stress and fertility quality of life among infertile couples. psychological resilience has a mediating effect on the infertility stress and fertility quality of life among infertile couples.

Objective:To explore the relationship between salivary alpha-amylase (SAA) and infertility stress in infertile women.Methods:A convenient sampling method was used to investigate the infertile women in the Reproductive Medicine Center of the First Affiliated Hospital of Zhengzhou University from April 2017 to December 2017. A total of 458 infertile women were examined using the SAA and the Fertility Problem Inventory (FPI). SAA level was measured using an enzyme-linked immunosorbent assay (ELISA) kit.Results:The total infertility stress score was 155.86±24.54. The family monthly income, the cause of infertility and the type of infertility were statistically different between different groups ( t=4.123, P=0.041; F=4.079, P<0.001; t=4.491, P=0.035). Pearson correlation analysis showed that SAA and social concern, relationship concern, need for parenthood, rejection of child-free life, sexual concern and total infertility stress were significantly correlated ( r=0.360, r=0.348, r=0.222, r=0.166, r=0.203, r=0.426, all P<0.001). Multiple linear regression results showed that infertility stress, infertility causes and types of infertility were factors influencing SAA. Conclusion:SAA was associated with infertility stress. Combined with SAA and FPI may assess the psychological stress more objectively for infertile women.

BACKGROUND:Early rehabilitation after total knee arthroplasty (TKA) can help the rapid functional recovery of knee,but some patients are fear of moving and refuse to do exercising because of kinesiophobia,thereby delaying functional recovery.Foreign study has confirmed that patients with cognitive behavioral therapy (CBT) can effectively alleviate kinesiophobia,but no related studies have been reported in China.OBJECTIVE:To explore the effectiveness of CBT on patients with kinesiophobia after TKA.METHODS:108 patients with kinesiophobia after TKA were recruited from Department of Orthopedics,the First Affiliated Hospital of Zhengzhou University,China between March 2014 and January 2015,and were then equivalently randomized into experimental and control groups using random number table.Both groups were subjected to conventional treatment,while the experimental group received extra CBT.The scores of Tampa Scale of Kinesiophobia and American Knee Society were evaluated immediately,1,3,and 6 months after hospital discharge;the hospitalization time and total hospitalization expenditure were compared between two groups immediately after discharge.RESULTS AND CONCLUSION:The scores of Tampa Scale of Kinesiophobia in the experimental group were significantly lower than those in the control group at different time points postoperatively (P ＜ 0.05).The scores of American Knee Society in the experimental group were significantly higher than those in the control group at 3 and 6 months after discharge and kept on rising (P ＜ 0.01),but showed no significant difference at discharge and 1 month after discharge (P ＞ 0.05).(2) The hospitalization time and total hospitalization expenditure in the experimental group were significantly lower than those in the control group (P ＜ 0.01).(3) To conclude,CBT cannot only shorten the hospitalization time and total hospitalization expenditure,but also relieve kinesiophobia,which is conductive for functional recovery of the knee.

Objective Currently, there are few articles about kinesiophobia in patients with total knee arthroplasty (TKA) in China.This study aims to investigate the incidence of kinesiophobia and its influencing factors in TKA patient, and provide evidence for the intervention of kinesiophobia.Methods A total of 298 TKA patients from our hospital were investigated by general information questionnaire, Tampa Scale of Kinesiophobia (TSK), Knee Self-Efficacy Scales, Simplified Coping Style Questionnaire and Social Support Rating Scale.Single-factor analysis and logistic regression analysis were conducted to explore influencing factors.Results The score of TSK was 38.50±13.52, and 31.88% of TKA patients reported kinesiophobia.Logistic regression analysis showed that duration of pain (OR=5.546, 95%CI: 2.143-14.353), education level (OR=0.145, 95%CI: 0.067-0.314), self efficacy(OR=0.606, 95%CI: 0.470-0.780), positive response (OR=0.784, 95%CI: 0.683-0.900), objective support (OR=0.807, 95%CI: 0.691-0.943) and utilization of social support (OR=0.507, 95%CI: 0.461-0.705) were factors influencing kinesiophobia in TKA patients.Conclusion Attention should be paid to the kinesiophobia in TKA patients, especially those influencing factors including duration of pain, education level, and objective support.Health care providers should encourage early stage rehabilitation exercise to improve the postoperative knee function of TKA patients.