The Expert Consensus on Clinical Application of Qinbaohong Zhike Oral Liquid in Treatment of Acute Bronchitis and Acute Attack of Chronic Bronchitis （GS/CACM 337-2023） was released by the China Association of Chinese Medicine on December 13^th， 2023. This expert consensus was developed by experts in methodology， pharmacy， and Chinese medicine in strict accordance with the development requirements of the China Association of Chinese Medicine （CACM） and based on the latest medical evidence and the clinical medication experience of well-known experts in the fields of respiratory medicine （pulmonary diseases） and pediatrics. This expert consensus defines the application of Qinbaohong Zhike oral liquid in the treatment of cough and excessive sputum caused by phlegm-heat obstructing lung， acute bronchitis， and acute attack of chronic bronchitis from the aspects of applicable populations， efficacy evaluation， usage， dosage， drug combination， and safety. It is expected to guide the rational drug use in medical and health institutions， give full play to the unique value of Qinbaohong Zhike oral liquid， and vigorously promote the inheritance and innovation of Chinese patent medicines.

Central venous pressure(CVP)is a commonly used hemodynamic index in clinical practice,and the accuracy of its measurement results is influenced by the measurement technical specifications.Based on research evidence and clinical practice,this article interprets the main content of the group standard of CVP measurement technology,and proposes suggestions for its use.It aims to guide clinical nursing staff to correctly understand the principles and methods of CVP measurement,and promote the standardization of nursing practice and the accuracy of measurement results.

Acute lung injury is an acute and criti-cal respiratory disease with complex pathogenesis,which has a high incidence rate and high mortality.At present,acute lung injury is mainly treated by mechanical ventilation,glucocorticoid anti-inflam-matory and extracorporeal membrane oxygen-ation.Traditional Chinese medicine also shows great potential in improving the clinical manifesta-tions and prognosis of patients.Quercetin is a fla-vonol compound,which can prevent and treat acute lung injury by anti-inflammatory,anti-oxida-tive stress,regulating programmed cell death,anti-bacterial and antiviral.This article summarizes the mechanism of action and research progress of quercetin in the treatment of acute lung injury,aiming to provide reference for subsequent re-search and clinical applications.

Dysfunction of the diaphragm is a common problem in mechanically ventilated patients and is closely related to various adverse outcomes.This review summarizes the evaluation methods of diaphragm function,the association between diaphragm dysfunction and adverse clinical outcomes in critically ill mechanically ventilated patients,and the protective effect of diaphragm function on adverse outcomes related to mechanical ventilation.The aim is to provide references for medical staff to optimize evaluation techniques,develop personalized nursing plans,and improve patients' quality of life and health outcomes.

Central venous pressure(CVP)is a commonly used hemodynamic index in clinical practice,and the accuracy of its measurement results is influenced by the measurement technical specifications.Based on research evidence and clinical practice,this article interprets the main content of the group standard of CVP measurement technology,and proposes suggestions for its use.It aims to guide clinical nursing staff to correctly understand the principles and methods of CVP measurement,and promote the standardization of nursing practice and the accuracy of measurement results.

Dysfunction of the diaphragm is a common problem in mechanically ventilated patients and is closely related to various adverse outcomes.This review summarizes the evaluation methods of diaphragm function,the association between diaphragm dysfunction and adverse clinical outcomes in critically ill mechanically ventilated patients,and the protective effect of diaphragm function on adverse outcomes related to mechanical ventilation.The aim is to provide references for medical staff to optimize evaluation techniques,develop personalized nursing plans,and improve patients' quality of life and health outcomes.

Acute lung injury is an acute and criti-cal respiratory disease with complex pathogenesis,which has a high incidence rate and high mortality.At present,acute lung injury is mainly treated by mechanical ventilation,glucocorticoid anti-inflam-matory and extracorporeal membrane oxygen-ation.Traditional Chinese medicine also shows great potential in improving the clinical manifesta-tions and prognosis of patients.Quercetin is a fla-vonol compound,which can prevent and treat acute lung injury by anti-inflammatory,anti-oxida-tive stress,regulating programmed cell death,anti-bacterial and antiviral.This article summarizes the mechanism of action and research progress of quercetin in the treatment of acute lung injury,aiming to provide reference for subsequent re-search and clinical applications.

Objective:To evaluate the effectiveness of a mobile extracorporeal cardiopulmonary resuscitation (ECPR) team in treating cardiac arrest (CA) in the mountainous regions of southwest Zhejiang Province, and to provide clinical insights for ECPR in patients with prolonged low blood flow time in such areas.Methods:A retrospective analysis was conducted on 55 CA patients treated with ECPR at Lishui People's Hospital from June 2020 to June 2024. These patients were compared with 55 CA patients treated with ECPR in urban areas during the same period. The mobile team from our center established ECMO support at county-level hospitals before transferring patients to our hospital's ECMO treatment center for further care. General patient data and blood gas analysis results before and 2 hours after ECPR were collected. Clinical data differences between the two groups were compared, and factors influencing patient prognosis were analyzed using univariate and multivariate Cox regression analyses.Results:The average age of the patients was (52.45 ± 15.66) years, with an average low blood flow time of 151.42 ± 49.31 minutes. The 30-day survival rate was 23.64%, and the rate of good neurological recovery was 18.18%. Although the survival rate and good neurological function rate were lower than those of ECPR patients in urban areas, the differences were not statistically significant ( P > 0.05). Univariate Cox analysis revealed that defibrillation rhythm, low blood flow time, pH before and after ECMO, blood lactate levels before and after ECMO, and hemoglobin significantly influenced the prognosis of ECPR patients ( P < 0.05). Multivariate Cox analysis identified post-ECMO pH ( HR = 0.037) and post-ECMO blood lactate levels ( HR = 1.078) as independent prognostic factors for ECPR patients ( P < 0.05). Conclusions:Despite the longer low blood flow time in CA patients from mountainous areas, the mobile ECPR team can effectively enhance the treatment success rate of these patients through ECPR.

Objective:To explore the current status and influencing factors of fatigue in patients with Cushing syndrome in China, so as to provide a basis for clinical interventions.Methods:Convenience sampling was used to select 260 inpatients with Cushing syndrome who met the inclusion and exclusion criteria in 9 ClassⅢ Grade A hospitals within the 7 geographic subregions of China from February to April 2023 for the study. General Information Questionnaire, the Chinese version of the Multidimensional Fatigue Inventory-20, Barthel Index, and Self-Rating Depression Scale were used for the survey.Results:A total of 260 questionnaires were distributed and 241 valid questionnaires were recovered, with an effective recovery rate of 92.7% (241/260). The MFI-20 score of 241 patients with Cushing syndrome was 58.00 (46.00, 64.00). 65.1% (157/241) of patients with Cushing syndrome suffered from fatigue, and 73.2% (115/157) of patients with fatigue exhibited multidimensional fatigue. Univariate analysis showed that there were statistically significant differences in fatigue scores among patients with Cushing syndrome with different cultural levels, recurrence frequency, activity of daily living, hypertension, and depression ( P<0.05). Multiple linear regression analysis showed that depression was a risk factor for fatigue in patients with Cushing syndrome, and the difference was statistically significant ( P<0.05) . Conclusions:Fatigue in patients with Cushing syndrome needs attention. Medical and nursing staff should pay close attention to the psychological status of patients with Cushing syndrome, encourage them to actively cope, alleviate their depression, in order to improve their fatigue.

Objective:To explore the latent profile characteristics of cancer-related fatigue (CRF) in breast cancer patients during the rehabilitation phase and to analyze the influencing factors of different latent profiles.Methods:A convenience sampling method was used to recruit 190 breast cancer patients in the rehabilitation phase from the follow-up cohort at Peking Union Medical College Hospital between March and May 2024. Data was collected using a general information questionnaire, the Cancer Fatigue Scale, the Self-Rating Anxiety Scale, the Self-Rating Depression Scale, the Pittsburgh Sleep Quality Index and the Visual Analogue Scale. Logistic regression analysis was conducted to identify the influencing factors of CRF latent profiles. A total of 190 questionnaires were distributed, and 183 valid responses were collected, yielding an effective response rate of 96.32% (183/190) .Results:Three latent profiles of CRF were identified: mild fatigue, moderate fatigue, and severe fatigue. Menopausal status, depressive symptoms, and pain scores were significant influencing factors of the CRF latent profiles ( P<0.05) . Conclusions:Cancer-related fatigue in breast cancer patients during the rehabilitation phase exhibits distinct latent profile characteristics. Early identification of profile types and associated influencing factors may provide a scientific basis for healthcare professionals to develop targeted clinical interventions to help patients alleviate fatigue.