[Objective]To explore the cultivation mode of innovative capacity of medical students in"curriculum-project-competition Continuity System",in order to cultivate high-quality medical talents with innovative thinking and strong practical capacity.[Methods]Taking the courses of Biochemistry and its related courses Medical Molecular Biology and Biochemistry Experiment for clinical medicine majors as a pilot,this research explores the training mode for innovative capabilities of medical talents in the new era by constructing a theoretical teaching system covering"basic theories,cutting-edge science and technology,and innovative thinking",adding innovative experiments featuring"independent topic selection,innovative design and cooperative discussion",and reforming the traditional project-competition mode.[Results]Through reform practices,the students'subjectivity in learning has been effectively strengthened,their awareness of independent innovation and exploration has been significantly stimulated,and their abilities to independently analyze and solve complex problems,as well as comprehensive innovative capabilities such as teamwork and interdisciplinary integration,have been systematically cultivated.The mastery rate of core knowledge in Biochemistry among the medical students of our university in the National Medical Licensing Examination has been continuously improving.Under the guidance of the teaching team,undergraduate students majoring in clinical medicine have been approved for multiple national/provincial college students'innovative training projects and"Xinmiao Program",published several SCI papers,and won various national/provincial science and technology competition awards.The quality of innovative talent training has achieved substantial improvement.[Conclusion]The"curriculum-project-competition continuity system"can effectively help students consolidate the foundation and promote the cultivation of students'innovation ability,providing an effective reference basis for the cultivation of innovative capacity of clinical medicine professionals in medical colleges and universities.

[Objective]To explore the cultivation mode of innovative capacity of medical students in"curriculum-project-competition Continuity System",in order to cultivate high-quality medical talents with innovative thinking and strong practical capacity.[Methods]Taking the courses of Biochemistry and its related courses Medical Molecular Biology and Biochemistry Experiment for clinical medicine majors as a pilot,this research explores the training mode for innovative capabilities of medical talents in the new era by constructing a theoretical teaching system covering"basic theories,cutting-edge science and technology,and innovative thinking",adding innovative experiments featuring"independent topic selection,innovative design and cooperative discussion",and reforming the traditional project-competition mode.[Results]Through reform practices,the students'subjectivity in learning has been effectively strengthened,their awareness of independent innovation and exploration has been significantly stimulated,and their abilities to independently analyze and solve complex problems,as well as comprehensive innovative capabilities such as teamwork and interdisciplinary integration,have been systematically cultivated.The mastery rate of core knowledge in Biochemistry among the medical students of our university in the National Medical Licensing Examination has been continuously improving.Under the guidance of the teaching team,undergraduate students majoring in clinical medicine have been approved for multiple national/provincial college students'innovative training projects and"Xinmiao Program",published several SCI papers,and won various national/provincial science and technology competition awards.The quality of innovative talent training has achieved substantial improvement.[Conclusion]The"curriculum-project-competition continuity system"can effectively help students consolidate the foundation and promote the cultivation of students'innovation ability,providing an effective reference basis for the cultivation of innovative capacity of clinical medicine professionals in medical colleges and universities.

Lignocellulose is the most abundant renewable biomass resource. Enzymatic breakdown of lignocellulose into oligosaccharides or monosaccharides is the key to exploit lignocellulosic biomass. However, traditional glycoside hydrolases are insufficient to degrade lignocellulose. The emergence of lytic polysaccharide monooxygenase, a novel enzyme for lignocellulose degradation, has enriched the deconstruction schema and accelerated the enzymatic conversion of polysaccharides, by introducing new chain breaks that allow hydrolases to initiate further degradation. Here, we review the discovery, classification and catalytic mechanism of the enzyme, as well as the methods for assaying its activity. The prospect for its application in feed additive, functional food and biofuel development is further discussed.