1.Latent profile analysis of self-acceptance in newly diagnosed young and middle-aged patients with type 2 diabetes mellitus
Wenxi GE ; Shumin AN ; Haohao ZHANG ; Gaofei REN ; Lingjiao MENG ; Yueqiao GAO
Chinese Journal of Modern Nursing 2025;31(23):3142-3148
Objective:To identify latent profile types of self-acceptance among newly diagnosed young and middle-aged patients with type 2 diabetes mellitus (T2DM), and to analyze the influencing factors.Methods:A convenience sampling method was used to recruit 162 patients with T2DM who visited the Department of Endocrinology at the First Affiliated Hospital of Zhengzhou University between March 2023 and August 2024. A general information questionnaire was used to collect demographic and clinical data. The Acceptance and Action Diabetes Questionnaire (AADQ), Type 2 Diabetes Stigma Assessment Scale (DSAS-2), Diabetes Knowledge Test 2 (DKT2), and e-Health Literacy Scale (eHEALS) were used to assess self-acceptance, diabetes-related stigma, diabetes knowledge, and electronic health literacy, respectively. Latent profile analysis (LPA) was performed to identify categories of self-acceptance based on AADQ scores. Logistic regression analysis was conducted to examine the influencing factors of self-acceptance profiles in young and middle-aged patients with T2DM. A total of 162 questionnaires were distributed, and 157 valid responses were collected, with an effective response rate of 96.91% (157/162) .Results:The mean AADQ score of the 157 patients was (46.64±10.34), ranging from 20 to 63, with a mean item score of (4.24±1.16). Three latent profile categories of self-acceptance were identified: the "high avoidance-low self-acceptance group" (28.66%, 45/157), the "moderate self-acceptance group" (47.13%, 74/157), and the "low avoidance-high self-acceptance group" (24.20%, 38/157). Logistic regression analysis showed that age, body mass index (BMI), diabetes-related stigma, diabetes knowledge, and electronic health literacy were significant influencing factors of self-acceptance profiles in young and middle-aged patients with T2DM ( P<0.05) . Conclusions:The level of self-acceptance in newly diagnosed young and middle-aged patients with type 2 diabetes mellitus remains suboptimal. Particular attention should be paid to patients who are younger, have a BMI below 24.0 kg/m 2, experience high levels of diabetes-related stigma, and have low levels of diabetes knowledge and electronic health literacy. Targeted education and management should be implemented based on patient characteristics.
2.Mediating effect of chronic disease resource utilization between health promotion behaviors and disease control in type 2 diabetes mellitus
Yueqiao GAO ; Shumin AN ; Wenqian GE ; Junhui XING
Chinese Journal of Modern Nursing 2025;31(26):3598-3603
Objective:To explore the mediating effect of chronic disease resource utilization between health promotion behaviors and disease control in patients with type 2 diabetes mellitus (T2DM) .Methods:Convenience sampling was used to select T2DM patients who attended the Department of Endocrinology and Metabolism of the First Affiliated Hospital of Zhengzhou University from September 2023 to October 2024 for the study. The survey was conducted using the General Information Questionnaire, Chronic Illness Resources Survey (CIRS), Health Promoting Lifestyle Profile-Ⅱ (HPLP-Ⅱ), and Control Status Scale for Diabetes (CSSD). Pearson correlation was used to analyze the relationship between chronic disease resource utilization, health promotion behaviors, and disease control. Structural equation modeling and mediating effect validation were performed using AMOS 21.0.Results:A total of 310 questionnaires were distributed, 292 valid questionnaires were recovered, with a valid recovery rate of 94.19%. The CIRS, HPLP-Ⅱ, and CSSD scores of 292 patients were (53.45±12.83), (145.85±28.40), and (89.41±24.57), respectively. CIRS scores were positively correlated with HPLP-Ⅱ scores and CSSD scores ( P<0.05), and HPLP-Ⅱ scores were positively correlated with CSSD scores ( P<0.05), with statistically significant differences. Mediating effect analysis showed that health promotion behaviors had a direct positive effect on disease control ( P=0.001), and chronic disease resource utilization had a partial mediating effect between health promotion behaviors and disease control ( P=0.001), with statistically significant differences and mediating effect accounting for 26.88% of the total effect (0.157/0.584) . Conclusions:Chronic disease resource utilization, health promotion behaviors, and disease control among T2DM patients are suboptimal, and there is room for improvement. Chronic disease resource utilization has a partial mediating effect between health promotion behaviors and disease control, which may guide clinical nursing practice.
3.Latent profile analysis of self-acceptance in newly diagnosed young and middle-aged patients with type 2 diabetes mellitus
Wenxi GE ; Shumin AN ; Haohao ZHANG ; Gaofei REN ; Lingjiao MENG ; Yueqiao GAO
Chinese Journal of Modern Nursing 2025;31(23):3142-3148
Objective:To identify latent profile types of self-acceptance among newly diagnosed young and middle-aged patients with type 2 diabetes mellitus (T2DM), and to analyze the influencing factors.Methods:A convenience sampling method was used to recruit 162 patients with T2DM who visited the Department of Endocrinology at the First Affiliated Hospital of Zhengzhou University between March 2023 and August 2024. A general information questionnaire was used to collect demographic and clinical data. The Acceptance and Action Diabetes Questionnaire (AADQ), Type 2 Diabetes Stigma Assessment Scale (DSAS-2), Diabetes Knowledge Test 2 (DKT2), and e-Health Literacy Scale (eHEALS) were used to assess self-acceptance, diabetes-related stigma, diabetes knowledge, and electronic health literacy, respectively. Latent profile analysis (LPA) was performed to identify categories of self-acceptance based on AADQ scores. Logistic regression analysis was conducted to examine the influencing factors of self-acceptance profiles in young and middle-aged patients with T2DM. A total of 162 questionnaires were distributed, and 157 valid responses were collected, with an effective response rate of 96.91% (157/162) .Results:The mean AADQ score of the 157 patients was (46.64±10.34), ranging from 20 to 63, with a mean item score of (4.24±1.16). Three latent profile categories of self-acceptance were identified: the "high avoidance-low self-acceptance group" (28.66%, 45/157), the "moderate self-acceptance group" (47.13%, 74/157), and the "low avoidance-high self-acceptance group" (24.20%, 38/157). Logistic regression analysis showed that age, body mass index (BMI), diabetes-related stigma, diabetes knowledge, and electronic health literacy were significant influencing factors of self-acceptance profiles in young and middle-aged patients with T2DM ( P<0.05) . Conclusions:The level of self-acceptance in newly diagnosed young and middle-aged patients with type 2 diabetes mellitus remains suboptimal. Particular attention should be paid to patients who are younger, have a BMI below 24.0 kg/m 2, experience high levels of diabetes-related stigma, and have low levels of diabetes knowledge and electronic health literacy. Targeted education and management should be implemented based on patient characteristics.
4.Mediating effect of chronic disease resource utilization between health promotion behaviors and disease control in type 2 diabetes mellitus
Yueqiao GAO ; Shumin AN ; Wenqian GE ; Junhui XING
Chinese Journal of Modern Nursing 2025;31(26):3598-3603
Objective:To explore the mediating effect of chronic disease resource utilization between health promotion behaviors and disease control in patients with type 2 diabetes mellitus (T2DM) .Methods:Convenience sampling was used to select T2DM patients who attended the Department of Endocrinology and Metabolism of the First Affiliated Hospital of Zhengzhou University from September 2023 to October 2024 for the study. The survey was conducted using the General Information Questionnaire, Chronic Illness Resources Survey (CIRS), Health Promoting Lifestyle Profile-Ⅱ (HPLP-Ⅱ), and Control Status Scale for Diabetes (CSSD). Pearson correlation was used to analyze the relationship between chronic disease resource utilization, health promotion behaviors, and disease control. Structural equation modeling and mediating effect validation were performed using AMOS 21.0.Results:A total of 310 questionnaires were distributed, 292 valid questionnaires were recovered, with a valid recovery rate of 94.19%. The CIRS, HPLP-Ⅱ, and CSSD scores of 292 patients were (53.45±12.83), (145.85±28.40), and (89.41±24.57), respectively. CIRS scores were positively correlated with HPLP-Ⅱ scores and CSSD scores ( P<0.05), and HPLP-Ⅱ scores were positively correlated with CSSD scores ( P<0.05), with statistically significant differences. Mediating effect analysis showed that health promotion behaviors had a direct positive effect on disease control ( P=0.001), and chronic disease resource utilization had a partial mediating effect between health promotion behaviors and disease control ( P=0.001), with statistically significant differences and mediating effect accounting for 26.88% of the total effect (0.157/0.584) . Conclusions:Chronic disease resource utilization, health promotion behaviors, and disease control among T2DM patients are suboptimal, and there is room for improvement. Chronic disease resource utilization has a partial mediating effect between health promotion behaviors and disease control, which may guide clinical nursing practice.
5.Analysis of amplitude-integrated electroencephalogram monitoring in hospitalized neonates
Shengjuan QIN ; Li ZHANG ; Jing LIU ; Yueqiao GAO ; Ruxin QIU ; Yanni LIU ; Jiuye GUO ; Zulin LU
Chinese Journal of General Practitioners 2021;20(8):858-862
Objective:To analized brain function monitoring results with amplitude- integrated electroencephalogram (aEEG) in neonatal ward.Methods:The clinical data of 1 370 newborns received aEEG monitoring in Neonatal Department of our hospital from September 2017 to August 2019 were retrospectively analyzed.Results:Among 1 370 neonates undergoing aEEG examination,abnormalities were demonstrated in 308 cases with an overall abnormal rate of 22.5%. The abnormal rate in critical neonates was 27.7% (240/868),while that in non-critical neonates was 13.6% (68/502) (χ2=36.304, P<0.01). Neonates with convulsion had the highest aEEG abnormal rate (57.1%, 16/28), followed by small for gestational age (SGA) (48.8%, 20/41), asphyxia (41.5%, 49/118), premature (31.1%, 92/296)and erythrocytosis (29.7%, 11/37). Among 308 cases of abnormal aEEG, the main types of abnormalities were abnormal background activity in 229 cases (74.4%),insignificant sleep-wake cycles in 139 cases (45.1%) and abnormal original EEG in 117 cases (40.0%). Among 308 cases of abnormal aEEG, 38.0%(117 cases) had corresponding clinical manifestations and 62.0%(191 cases) had no clinical manifestations. The sensitivity of aEEG monitoring is 73.6%(117/159), and the specificity is 84.2%(1 020/1 211). Conclusions:The abnormal rate of aEEG is high in hospitalized neonates,especially in critically ill neonates. It is necessary to carry out routine aEEG examination for hospitalized neonates in order to early detect brain function damage.
6.Several neglected but common risk factors for neonatal brain injury
Jing LIU ; Li ZHANG ; Yueqiao GAO
Chinese Journal of Applied Clinical Pediatrics 2020;35(23):1761-1765
Clinicians are familiar with neonatal brain damage caused by severe asphyxia, hypoxia and premature birth, but enough attention has not been paid on the correlation between cesarean section, polycythemia, disseminated intravascular coagulation, patent ductus arteriosus, and non-invasive high-frequency oscillatory ventilation and neonatal brain damage.Which would be introduced in this paper to further improve neonatal prognosis.
7.Ultrasound diagnosis of neonatal fracture
Jing LIU ; Huali WEI ; Huirong ZHAO ; Li ZHANG ; Ruxin QIU ; Yueqiao GAO ; Chen CHEN
Chinese Journal of Perinatal Medicine 2020;23(4):245-248
Objective:To investigate the feasibility and characteristics of ultrasound imaging in diagnosing fractures in neonates.Methods:Thirty neonates with bone fracture in Beijing Chaoyang District Maternal and Child Healthcare Hospital during January 2018 to June 2019 were retrospectively recruited. The causes and ultrasound imaging features of these cases were analyzed. The ultrasound findings were compared with the results of X-ray examination.Results:Among the 30 cases, 29 (96.7%) were diagnosed as fracture due to birth trauma, including 28 (93.3%) of clavicle fracture and one (3.3%) of humerus fracture, and one (3.3%) with rib fracture probably caused by metabolic osteopathy. The ultrasound imaging characteristics included interruption of bone continuity, dislocation and/or angulation of fracture ends, and callus formation during recovery. All of the 30 cases were diagnosed by ultrasound. However, X-ray examination failed in the diagnosis of one clavicle fracture.Conclusions:Ultrasound is an accurate and reliable method for the diagnosis of neonatal fracture. The main characteristics of ultrasound imaging include interruption of bone continuity, dislocation and/or angulation of fracture ends and callus formation.
8. Application of ultrasound monitoring for evaluation of neonatal peripherally inserted central catheter tip localization in newborns
Xiaoling REN ; Yajuan CHEN ; Jing LIU ; Man WANG ; Jia SHEN ; Yueqiao GAO ; Ruxin QIU
Chinese Journal of Applied Clinical Pediatrics 2019;34(18):1398-1401
Objective:
To investigate the value of ultrasound in the localization of peripherally inserted central catheter (PICC) in neonates.
Methods:
A retrospective analysis of the PICC catheterization was conducted at Department of Neonatology, Beijing Chaoyang District Maternal and Child Healthcare Hospital from June 2017 to December 2018.The ultrasound monitoring was performed immediately after PICC catheterization.The probe was placed into the midline position of the lower xiphoid or the subclavian parasternal line for scanning, and it would be the PICC if a high-echo " equal sign" was observed by ultrasound.It was believed that the PICC was successfully placed when ultrasound detected that the PICC tip was located in the junction of inferior vena cava or superior vena cava in the right atrium.
Results:
(1)Among 112 infants with PICC catheterization, 103 cases (92.0%) were accurately placed, 9 cases (8.0%) were not placed in the ideal site, among them, 2 cases were too deep, 4 cases were too shallow and 3 cases were catheter heterotopia.The tip position was accurate after the readjustment under ultrasound monitoring in those patients whose the first ultrasound showed the tip position was not ideal.(2)The PICC indwelling time was as short as 2 days (removed due to severe arrhythmia) and as long as 56 days with an average of (15.1±10.7) days.(3)The catheter-related complications occurred in 3 cases with an incidence of 2.7%.
Conclusions
Using ultrasound to determine the PICC tips position is accurate and reliable, which is worthy of extensive application in the neonatal wards.
9. Lung ultrasound for diagnosis of neonatal pulmonary hemorrhage
Jing LIU ; Ruxin QIU ; Yueqiao GAO
Chinese Journal of Perinatal Medicine 2019;22(10):740-743
Pulmonary hemorrhage is a common critical disease in neonates, with high mortality. Early and accurate diagnosis is the key to successful treatment. Recently, lung ultrasound has been successfully used to diagnose neonatal pulmonary hemorrhage. Main ultrasonographic manifestations of neonatal pulmonary hemorrhage are described in this article, including shred sign, lung consolidation with air bronchogram, pleural effusion, lung edema, pleural line abnormality and A-line disappearance.

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