Objective To explore the application of low-concentration contrast agent and low tube voltage(dual-low)scanning technology combined with iterative reconstruction technique in computed tomography perfusion(CTP)scanning for patients with acute cerebral infarction(ACI).Methods A retrospective analysis was conducted on 120 patients diagnosed with ACI at Gansu Second People's Hospital from December 2018 to December 2022.All patients underwent CTP examination,and according to CTP contrast agent and tube voltage,they were divided into dual-low group(n=64,low-concentration contrast agent with an iodine content of 270 mgI/mL,low tube voltage of 80 kV)and control group(n=56,conventional concentration contrast agent with an iodine content of 350 mgI/mL,standard tube voltage of 120 kV).Images quality was compared between two groups,with the intraclass correlation coefficient used to evaluate the consistency of image quality.The radiation dose,intake of ioversol injection,CT value at M1 segment of the middle cerebral artery,signal-to-noise ratio,and contrast-to-noise ratio were also compared between two groups.Results The difference in CTP image quality between dual-low group and control group was trivial(P>0.05).The dual-low group exhibited lower dose-length product,effective radiation dose,and intake of ioversol injection than control group(P<0.05).No significant differences were observed in CT value at M1 segment of the middle cerebral artery,signal-to-noise ratio or contrast-to-noise ratio between two groups(P>0.05).Conclusion The application of dual-low scanning technology combined with iterative reconstruction algorithm can reduce intake of contrast agent and radiation dose while ensuring CTP images quality in ACI patients.

Objective To explore the application of low-concentration contrast agent and low tube voltage(dual-low)scanning technology combined with iterative reconstruction technique in computed tomography perfusion(CTP)scanning for patients with acute cerebral infarction(ACI).Methods A retrospective analysis was conducted on 120 patients diagnosed with ACI at Gansu Second People's Hospital from December 2018 to December 2022.All patients underwent CTP examination,and according to CTP contrast agent and tube voltage,they were divided into dual-low group(n=64,low-concentration contrast agent with an iodine content of 270 mgI/mL,low tube voltage of 80 kV)and control group(n=56,conventional concentration contrast agent with an iodine content of 350 mgI/mL,standard tube voltage of 120 kV).Images quality was compared between two groups,with the intraclass correlation coefficient used to evaluate the consistency of image quality.The radiation dose,intake of ioversol injection,CT value at M1 segment of the middle cerebral artery,signal-to-noise ratio,and contrast-to-noise ratio were also compared between two groups.Results The difference in CTP image quality between dual-low group and control group was trivial(P>0.05).The dual-low group exhibited lower dose-length product,effective radiation dose,and intake of ioversol injection than control group(P<0.05).No significant differences were observed in CT value at M1 segment of the middle cerebral artery,signal-to-noise ratio or contrast-to-noise ratio between two groups(P>0.05).Conclusion The application of dual-low scanning technology combined with iterative reconstruction algorithm can reduce intake of contrast agent and radiation dose while ensuring CTP images quality in ACI patients.