Objective:To investigate the effect of telephone follow-up-based pharmaceutical care on medication compliance and safety in discharged patients with type 2 diabetes mellitus.Methods:Type 2 diabetes mellitus patients, who were discharged from Beijing Tongren Hospital, Capital Medical University from January 2019 to December 2019 and with hemoglobin A1c (HbA1c) <9% during hospitalization were enrolled. Patients were divided into routine follow-up group and telephone follow-up group according to the post-discharge follow-up method. Patients in the routine follow-up group received routine pharmaceutical care and were followed up for 6 months after discharge, including outpatient follow-up once every 3 months and HbA1c test at the 6th month. On this basis, patients in the telephone follow-up group received pharmaceutical care by clinical pharmacists using telephone follow-up method, which was performed once every 2 weeks for the first 3 months after discharge and once a month for the next 3 months. The clinical pharmacists established follow-up registration files for patients in the 2 groups to record the condition of the patients on discharge and results of each follow-up. Scores of the "Diabetes Self-Management Scale (Chinese version)" score (DSMQ score, with a total score of 48 points, the higher the score, the better the self-management ability of the patient), "Chinese Version Morisky Medication Adherence Scale-8" score (Morisky score, with a total score of 8 points, regarding 6 to 8 points as good compliance), and blood glucose control results (evaluation index is HbA1c level, HbA1c <7.0% was used as the standard to calculate the compliance rate) 6 months after discharge and the incidences of adverse drug events during the follow-up period in patients between the 2 groups were compared.Results:A total of 95 patients were enrolled in the analysis, including 48 in the telephone follow-up group and 47 in the routine follow-up group. Differences in gender and age distribution, body mass index, DSMQ score, and HbA1c level and compliance rate on discharge in patients in the 2 groups were not statistically significant (all P>0.05). Six months after discharge, both the DSMQ score and Morishy score in the telephone follow-up group were higher than those in the routine follow-up group [ (38.1±4.4) vs. (34.3±4.1) points, P<0.001; (6.5±1.2) vs. (5.7±1.0) points, P<0.001]; the proportion of patients with good medication compliance in the telephone follow-up group were higher than those in the routine follow-up group [81.3% (39/48) vs. 40.4% (19/47) , P=0.031]; the HbA1c level was lower and the HbA1c compliance rate was higher in the telephone follow-up group than those in the routine follow-up group[(6.2±1.2)% vs. (6.7±1.4)%, P=0.042; 72.9% vs. 51.1%, P=0.028]; the incidence of adverse drug events in the telephone follow-up group was lower than that in the routine follow-up group [6.2% (3/48) vs. 25.5% (12/47), P=0.010]. Adverse drug events occurred in patients mainly included hypoglycemia, fatty induration or infection at the insulin injection site, and gastrointestinal reactions. Conclusion:Telephone follow-up-based pharmaceutical care can effectively improve the self-management ability of patients with type 2 diabetes after discharge, help patients maintain good medication compliance, thereby improving the blood glucose control effects and to a certain extent reducing the occurrence of adverse drug events.

Objective:To investigate the effect of telephone follow-up-based pharmaceutical care on medication compliance and safety in discharged patients with type 2 diabetes mellitus.Methods:Type 2 diabetes mellitus patients, who were discharged from Beijing Tongren Hospital, Capital Medical University from January 2019 to December 2019 and with hemoglobin A1c (HbA1c) <9% during hospitalization were enrolled. Patients were divided into routine follow-up group and telephone follow-up group according to the post-discharge follow-up method. Patients in the routine follow-up group received routine pharmaceutical care and were followed up for 6 months after discharge, including outpatient follow-up once every 3 months and HbA1c test at the 6th month. On this basis, patients in the telephone follow-up group received pharmaceutical care by clinical pharmacists using telephone follow-up method, which was performed once every 2 weeks for the first 3 months after discharge and once a month for the next 3 months. The clinical pharmacists established follow-up registration files for patients in the 2 groups to record the condition of the patients on discharge and results of each follow-up. Scores of the "Diabetes Self-Management Scale (Chinese version)" score (DSMQ score, with a total score of 48 points, the higher the score, the better the self-management ability of the patient), "Chinese Version Morisky Medication Adherence Scale-8" score (Morisky score, with a total score of 8 points, regarding 6 to 8 points as good compliance), and blood glucose control results (evaluation index is HbA1c level, HbA1c <7.0% was used as the standard to calculate the compliance rate) 6 months after discharge and the incidences of adverse drug events during the follow-up period in patients between the 2 groups were compared.Results:A total of 95 patients were enrolled in the analysis, including 48 in the telephone follow-up group and 47 in the routine follow-up group. Differences in gender and age distribution, body mass index, DSMQ score, and HbA1c level and compliance rate on discharge in patients in the 2 groups were not statistically significant (all P>0.05). Six months after discharge, both the DSMQ score and Morishy score in the telephone follow-up group were higher than those in the routine follow-up group [ (38.1±4.4) vs. (34.3±4.1) points, P<0.001; (6.5±1.2) vs. (5.7±1.0) points, P<0.001]; the proportion of patients with good medication compliance in the telephone follow-up group were higher than those in the routine follow-up group [81.3% (39/48) vs. 40.4% (19/47) , P=0.031]; the HbA1c level was lower and the HbA1c compliance rate was higher in the telephone follow-up group than those in the routine follow-up group[(6.2±1.2)% vs. (6.7±1.4)%, P=0.042; 72.9% vs. 51.1%, P=0.028]; the incidence of adverse drug events in the telephone follow-up group was lower than that in the routine follow-up group [6.2% (3/48) vs. 25.5% (12/47), P=0.010]. Adverse drug events occurred in patients mainly included hypoglycemia, fatty induration or infection at the insulin injection site, and gastrointestinal reactions. Conclusion:Telephone follow-up-based pharmaceutical care can effectively improve the self-management ability of patients with type 2 diabetes after discharge, help patients maintain good medication compliance, thereby improving the blood glucose control effects and to a certain extent reducing the occurrence of adverse drug events.