Objective To explore the effect of a subcutaneous microintroducer tunnelling technique on placement of tunnelled peripherally inserted central catheter(TPICC).Methods A total of 521 patients undergoing chemotherapy with peripherally inserted central catheters in our hospital from January 2021 to February 2023 were enrolled in this study.A total of 313 patients who received the subcutaneous microintroducer tunnelling were assigned to a tunnelling group and 208 who did not have the subcutaneous tunnelling were assigned to the non-tunnelling group.The two groups were compared in terms of the incidence of catheter displacement,blood leakage,seepage,subcutaneous congestion,catheter associated infection,catheter blockage,catheter-associated thrombosis,nerve injury,lymphorrhagia,unplanned withdraw of catheter,difficulty in catheter withdraw,and catheter damage.Results The subcutaneous microintroducer tunnelling group exhibited a significantly lower incidence of catheter displacement,blood leakage,and catheter associated infections compared to those in the non-tunnelling group(all P<0.05).However,there was no significant difference between the two groups in the incidence of nerve injury,seepage subcutaneous congestion,lymphorrhagia,difficulty in catheter withdraw,catheter damage,incidence of catheter blockage,catheter-associated thrombosis,and unplanned withdraw of catheter(all P>0.05).Conclusion The subcutaneous microintroducer tunnelling is a safe and effective technique.It effectively reduces the rates of post-placement complications in TPICC.

Objective To explore the effect of a subcutaneous microintroducer tunnelling technique on placement of tunnelled peripherally inserted central catheter(TPICC).Methods A total of 521 patients undergoing chemotherapy with peripherally inserted central catheters in our hospital from January 2021 to February 2023 were enrolled in this study.A total of 313 patients who received the subcutaneous microintroducer tunnelling were assigned to a tunnelling group and 208 who did not have the subcutaneous tunnelling were assigned to the non-tunnelling group.The two groups were compared in terms of the incidence of catheter displacement,blood leakage,seepage,subcutaneous congestion,catheter associated infection,catheter blockage,catheter-associated thrombosis,nerve injury,lymphorrhagia,unplanned withdraw of catheter,difficulty in catheter withdraw,and catheter damage.Results The subcutaneous microintroducer tunnelling group exhibited a significantly lower incidence of catheter displacement,blood leakage,and catheter associated infections compared to those in the non-tunnelling group(all P<0.05).However,there was no significant difference between the two groups in the incidence of nerve injury,seepage subcutaneous congestion,lymphorrhagia,difficulty in catheter withdraw,catheter damage,incidence of catheter blockage,catheter-associated thrombosis,and unplanned withdraw of catheter(all P>0.05).Conclusion The subcutaneous microintroducer tunnelling is a safe and effective technique.It effectively reduces the rates of post-placement complications in TPICC.

Recent clinical research shows that the local treatment of primary tumor can improve cancer-specific-survival and overall-survival for metastatic prostate cancer patients.Differ with lymph node metastasis,there is not enough high-level randomized controlled trial data to decide whether the prostate cancer patients with bone metastasis will be benefited from local treatment,meanwhile,it also needs to figure out the factors influencing prognosis of patients.How to efficiently combine multi local treatment with system treatment is a current research hot spot as well.