Objective To compare the effects of remimazolam and propofol on the quality of recovery in children with strabismus surgery under general anesthesia.Methods A total of 100 children scheduled for strabismus surgery were enrolled and randomly assigned to the remimazolam group(R group)or the propofol group(P group).Children in the R group received intravenous remimazolam 0.2 mg/kg,followed by remimazolam infusion at a rate of 1-3 mg·kg-1·h-1.Children in the P group received intravenous propofol 2.5 mg/kg,followed by propofol infusion at a rate of 4-12 mg·kg-1·h-1.The intraoperative hypotension,extubation time,post-anesthesia care unit(PACU)stay time,postoperative nausea and vomiting(PONV),and incidence of emergence agitation were recorded in the two groups of patients.Emergence agitation was assessed using the Pediatric Anesthesia Emergence Delirium(PAED)scale.Results A total of 49 and 50 children were included in the R group and the P group,respectively.Compared with the P group,the R group showed a significant increase in mean arterial pressure and heart rate at 15 minutes after the start of surgery(P<0.05).The incidence of intraoperative hypotension(14.3%vs.46.0%)and emergence agitation(14.3%vs.38.0%)were significantly lower in the R group than those in the P group(P<0.05).The extubation time[(15.7±5.8)min vs.(11.3±4.6)min],PACU stay time[(27.5±7.3)min vs.(23.2±6.5)min]were significantly longer in the R group than those in the P group,while the highest PAED score[(7.6±2.9)vs.(9.4±3.3)]was significantly lower in the R group than that in the P group,(P<0.05).Conclusion Compared with propofol,remimazolam can reduce the risk of emergence agitation in children undergoing strabismus surgery under general anesthesia,and has advantages in maintaining hemodynamic stability during surgery.

Objective To compare the effects of remimazolam and propofol on the quality of recovery in children with strabismus surgery under general anesthesia.Methods A total of 100 children scheduled for strabismus surgery were enrolled and randomly assigned to the remimazolam group(R group)or the propofol group(P group).Children in the R group received intravenous remimazolam 0.2 mg/kg,followed by remimazolam infusion at a rate of 1-3 mg·kg-1·h-1.Children in the P group received intravenous propofol 2.5 mg/kg,followed by propofol infusion at a rate of 4-12 mg·kg-1·h-1.The intraoperative hypotension,extubation time,post-anesthesia care unit(PACU)stay time,postoperative nausea and vomiting(PONV),and incidence of emergence agitation were recorded in the two groups of patients.Emergence agitation was assessed using the Pediatric Anesthesia Emergence Delirium(PAED)scale.Results A total of 49 and 50 children were included in the R group and the P group,respectively.Compared with the P group,the R group showed a significant increase in mean arterial pressure and heart rate at 15 minutes after the start of surgery(P<0.05).The incidence of intraoperative hypotension(14.3%vs.46.0%)and emergence agitation(14.3%vs.38.0%)were significantly lower in the R group than those in the P group(P<0.05).The extubation time[(15.7±5.8)min vs.(11.3±4.6)min],PACU stay time[(27.5±7.3)min vs.(23.2±6.5)min]were significantly longer in the R group than those in the P group,while the highest PAED score[(7.6±2.9)vs.(9.4±3.3)]was significantly lower in the R group than that in the P group,(P<0.05).Conclusion Compared with propofol,remimazolam can reduce the risk of emergence agitation in children undergoing strabismus surgery under general anesthesia,and has advantages in maintaining hemodynamic stability during surgery.

A novel technology is proposed for non-contact and real-time detection of atrial fibrillation using millimeter-wave radar.A 60 GHz PCR millimeter wave radar is used to continuously detect the chest echo signal of the subject.After signal acquisition,I-Q signal is generated through I-Q demodulation,and the signal phase information is extracted using effective points phase trend evaluation for obtaining the signals from oscillations in the chest wall,from which the respiratory signals and cardiac signals are extracted through digital filtering for the analysis of cardiac movement.Whether the atrial fibrillation occurs or not is determined by the characteristics of atrial fibrillation wave in the time domain.The effective points phase trend evaluation for extracting more accurate signal phase information and the time-domain method for real-time atrial fibrillation detection are the innovations of the study.The experimental results show that the proposed method achieves a detection accuracy of 99.2%in clinic.

BACKGROUND:Vascularuzed fibular graft is one of the effective methods for repair of large segmental bone defects in the extremities OBJECTIVE:To explore the clinical effects of vascularized fibular graft for repairing large segmental bone defects in the extremities. METHODS:Twenty-eight non-malignant patients who received vascularized fibular graft for repairing large segmental bone defects in the extremities and were folowed up for more than 20 months were enroled. After lesion removal, vascularized fibula bone graft was used to repair the bone defects. If cases combined with soft tissue defects, fibula flap or anterolateral thigh flap was adopted. RESULTS AND CONCLUSION: Al patients were folowed up for 20 months to 6 years. The grafted bones were healed with the surrounding bone at 3-8 months after fibula bone grafting. The grafted bone was enlarged near to the diameter of recipient bone at 10-22 months after grafting. Based on the Enneking system, the average score of large segmental tibia bone defects was 24.2 points with 81% limb function recovered and 94.1% patient satisfaction; the average score of large segmental femur bone defects was 26.3 points with 87.7% limb function recovered and 100% patient satisfaction; the average score of large segmental bone defects of the distal radius and ulna was 21.75 points with 72.5% limb function recovered and 100% patient satisfaction. These findings reveal that vascularized fibular graft for repairing large segmental bone defects in extremities can effectively promote bone healing and reduce disability, infection, amputation rate; moreover, patients are satisfied with the postoperative recovery of limb function.

BACKGROUND:For the patients with proximal humeral fractures or serious complications, internal fixation is the effective method that cannot influence the activity of the shoulder with few trauma. OBJECTIVE:To investigate the biomechanical characteristics of percutaneous plate combined with anatomical locking plate fixation for the treatment of proximal humeral fractures. METHODS:Seventy-five patients with proximal humeral fractures were selected from Department of Orthopedics, the Third Affiliated Hospital of Guangzhou Medical University between March 2007 and December 2011. The healing after the locking plate fixation and the shoulder joint score after internal fixation were observed. The biomechanical advantages of locking plate fixation in the treatment of proximal humeral fractures were analyzed. RESUTLS AND CONCLUSION:Al the 75 patients were fol owed up for 6-24 months, average 13.3 months. The X-ray film after treatment showed al the screws were in correct position with satisfactory fracture reduction, and the fractures were healed without neurovascular injury and humeral head necrosis;one case had infection and healed after treatment, 72 cases had no shoulder pain, while three cases had occasional shoulder pain. The Neer score was excel ent in 57 cases, good in 11 cases, moderate in seven cases and poor in none, and the excel ent and good rate was 90.7%. Compared with other fixation implants, the locking plate fixation in the treatment of proximal humeral fractures has the advantages of high fixation strength and satisfactory effect, becoming the first choice for the clinical treatment of proximal humeral fractures.