Objective:To analyze the value of carotid plaque neovascularization grading in predicting the risk of ischemic stroke.Methods:Thirty-five patients with ischemic stroke and carotid atherosclerotic plaques, admitted to Ningbo No. 4 Hospital from June 2022 to June 2024, were retrospectively included in the study group. Additionally, 25 patients with only carotid atherosclerotic plaques admitted during the same period were included in the control group. Ultrasound examination was performed to assess the neovascularization grading in the carotid atherosclerotic plaques of the enrolled patients. The clinical data of both groups were compared. Pearson's correlation analysis was performed to analyze the relationship between D-dimer levels, neovascular grading in the plaques, and the onset of ischemic stroke. Logistic regression was applied to identify multiple risk factors for the onset of ischemic stroke.Results:D-dimer levels and the percentages of grades Ⅲ and Ⅳ neovascularization in the study group were (845.68 ± 101.02) μg/L, 51.4% (18/35), and 31.4% (11/35), respectively. These values were significantly higher than those in the control group [(446.89 ± 103.25) μg/L, 24.0% (6/25), 8.0% (2/25)]. The percentage of grade Ⅱ neovascularization in the study group was significantly lower than that in the control group [5.7% (2/35) vs. 36.0% (9/25)]. All differences between the two groups were statistically significant ( t = 7.82, χ2 = 8.93, 4.57, 4.72, P < 0.001, P = 0.003, P = 0.033, P = 0.030). Pearson's correlation test indicated a positive correlation between D-dimer level, carotid plaque neovascularization grade, and the onset of ischemic stroke ( r = 0.825, 0.826, both P < 0.05). Multivariate logistic regression analysis showed that D-dimer level and carotid plaque neovascularization grade were significant risk factors associated with the incidence of ischemic stroke ( OR = 3.414, 3.449, both P < 0.05). Conclusions:D-dimer level and carotid plaque neovascularization grade have high value in predicting the risk of ischemic stroke.

Objective:To analyze the value of carotid plaque neovascularization grading in predicting the risk of ischemic stroke.Methods:Thirty-five patients with ischemic stroke and carotid atherosclerotic plaques, admitted to Ningbo No. 4 Hospital from June 2022 to June 2024, were retrospectively included in the study group. Additionally, 25 patients with only carotid atherosclerotic plaques admitted during the same period were included in the control group. Ultrasound examination was performed to assess the neovascularization grading in the carotid atherosclerotic plaques of the enrolled patients. The clinical data of both groups were compared. Pearson's correlation analysis was performed to analyze the relationship between D-dimer levels, neovascular grading in the plaques, and the onset of ischemic stroke. Logistic regression was applied to identify multiple risk factors for the onset of ischemic stroke.Results:D-dimer levels and the percentages of grades Ⅲ and Ⅳ neovascularization in the study group were (845.68 ± 101.02) μg/L, 51.4% (18/35), and 31.4% (11/35), respectively. These values were significantly higher than those in the control group [(446.89 ± 103.25) μg/L, 24.0% (6/25), 8.0% (2/25)]. The percentage of grade Ⅱ neovascularization in the study group was significantly lower than that in the control group [5.7% (2/35) vs. 36.0% (9/25)]. All differences between the two groups were statistically significant ( t = 7.82, χ2 = 8.93, 4.57, 4.72, P < 0.001, P = 0.003, P = 0.033, P = 0.030). Pearson's correlation test indicated a positive correlation between D-dimer level, carotid plaque neovascularization grade, and the onset of ischemic stroke ( r = 0.825, 0.826, both P < 0.05). Multivariate logistic regression analysis showed that D-dimer level and carotid plaque neovascularization grade were significant risk factors associated with the incidence of ischemic stroke ( OR = 3.414, 3.449, both P < 0.05). Conclusions:D-dimer level and carotid plaque neovascularization grade have high value in predicting the risk of ischemic stroke.