1.The impact of the preoperative value of phase angle in bioelectrical impedance analysis on postoperative complications after pancreaticoduodenectomy
Young Jae CHO ; Yoon Soo CHAE ; Go-Won CHOI ; Inhyuck LEE ; Younsoo SEO ; Seulah PARK ; Youngmin HAN ; Hye-sol JUNG ; Wooil KWON ; Jin-Young JANG ; Joon Seong PARK
Annals of Hepato-Biliary-Pancreatic Surgery 2026;30(1):67-75
Background:
s/Aims: Phase angle (PhA), as measured by bioelectrical impedance analysis, provides insights into hydration and nutritional status, making it a prognostic indicator of frailty. While low preoperative PhA has been linked to postoperative complications in cancer patients, its predictive value in individuals undergoing pancreaticoduodenectomy (PD) has not been thoroughly investigated.This study aims to evaluate the clinical utility of preoperative PhA in predicting postoperative complications for patients undergoing PD.
Methods:
Among 41 patients who underwent PD at Seoul National University Hospital between September and December 2024, 35 were included in the analysis after excluding 6 patients who had concomitant blood vessel or other organ resections. Patients were divided into low (Comprehensive Complication Index [CCI] ≤ 20) and high (CCI > 20) complication groups based on the CCI, derived from the Clavien–Dindo classification. The differences in PhA between the two groups were analyzed, and logistic regression was performed to assess the relationship between PhA and CCI.
Results:
The mean PhA was significantly lower in the high-CCI group compared to the low-CCI group (5.7° vs. 6.7°, p = 0.025). Multivariate logistic regression analysis indicated that PhA (odds ratio: 0.17; 95% confidence interval: 0.04–0.68; p = 0.012) was an independent predictor of high CCI. A low preoperative PhA was associated with an increased risk of postoperative complications following PD.
Conclusions
Preoperative PhA may serve as a valuable predictive indicator of postoperative complications after PD, enabling the identification of patients who could benefit from preoperative prehabilitation, including nutritional support.
2.Nephrogenic diabetes insipidus secondary to COVID-19 infection in a patient on lithium medication: a case report
Jong-In CHOI ; Somin LEE ; Hyun Lee KIM ; Jong-Hoon CHUNG ; Byung Chul SHIN ; Youngmin YOON
Journal of the Korean Society of Emergency Medicine 2025;36(1):41-44
Nephrogenic diabetes insipidus (NDI) is characterized by polyuria and polydipsia, high serum osmolality, and low urine osmolality because of resistance to antidiuretic hormone. Lithium is commonly used to treat psychiatric disorders, and NDI is one of the common renal side effects of lithium therapy. On the other hand, NDI induced by lithium medication in a patient after a coronavirus disease-19 (COVID-19) infection has not been reported. This paper presents a patient who developed new-onset NDI secondary to a COVID-19 infection despite being on a stable lithium dose for several years. This case highlights the importance of considering a COVID-19 infection as a possible cause of NDI in patients taking lithium medication.
3.Nephrogenic diabetes insipidus secondary to COVID-19 infection in a patient on lithium medication: a case report
Jong-In CHOI ; Somin LEE ; Hyun Lee KIM ; Jong-Hoon CHUNG ; Byung Chul SHIN ; Youngmin YOON
Journal of the Korean Society of Emergency Medicine 2025;36(1):41-44
Nephrogenic diabetes insipidus (NDI) is characterized by polyuria and polydipsia, high serum osmolality, and low urine osmolality because of resistance to antidiuretic hormone. Lithium is commonly used to treat psychiatric disorders, and NDI is one of the common renal side effects of lithium therapy. On the other hand, NDI induced by lithium medication in a patient after a coronavirus disease-19 (COVID-19) infection has not been reported. This paper presents a patient who developed new-onset NDI secondary to a COVID-19 infection despite being on a stable lithium dose for several years. This case highlights the importance of considering a COVID-19 infection as a possible cause of NDI in patients taking lithium medication.
4.Nephrogenic diabetes insipidus secondary to COVID-19 infection in a patient on lithium medication: a case report
Jong-In CHOI ; Somin LEE ; Hyun Lee KIM ; Jong-Hoon CHUNG ; Byung Chul SHIN ; Youngmin YOON
Journal of the Korean Society of Emergency Medicine 2025;36(1):41-44
Nephrogenic diabetes insipidus (NDI) is characterized by polyuria and polydipsia, high serum osmolality, and low urine osmolality because of resistance to antidiuretic hormone. Lithium is commonly used to treat psychiatric disorders, and NDI is one of the common renal side effects of lithium therapy. On the other hand, NDI induced by lithium medication in a patient after a coronavirus disease-19 (COVID-19) infection has not been reported. This paper presents a patient who developed new-onset NDI secondary to a COVID-19 infection despite being on a stable lithium dose for several years. This case highlights the importance of considering a COVID-19 infection as a possible cause of NDI in patients taking lithium medication.
5.Antler abnormalities with testicular atrophy in a wild roe deer (Capreolus pygargus): a case report
Dayoung CHOI ; Da-Ye NAM ; Jae-Hoon KIM ; Jinho JANG ; Youngmin YUN ; Ji-Youl JUNG
Korean Journal of Veterinary Research 2025;65(4):e28-
Deer antlers are regenerate annually under hormonal control, particularly testosterone. Here, we report a case of antler deformity associated with testicular atrophy in a wild roe deer (Capreolus pygargus) in South Korea. Both antlers were abnormally enlarged and entangled in agricultural netting. Gross and histopathological examination revealed severe testicular atrophy, interstitial fibrosis, and hindlimb muscle necrosis. Serum testosterone was extremely low (0.032 ng/mL). These findings explain the abnormal antler growth and suggest susceptibility to capture myopathy due to hormonal imbalance. This is the first documented case in South Korea linking antler abnormalities to testicular atrophy in wild roe deer, highlighting the impact of endocrine disruption on cervid health.
6.Surface roughness of flowable bulk fill composite resin by different polishing protocols
Youn-Su CHOI ; Youngmin KWON ; Jin-Woo KIM ; Se-Hee PARK ; Kyung-Mo CHO
Journal of Dental Rehabilitation and Applied Science 2025;41(3):188-197
Purpose:
This study aimed to evaluate the surface characteristics of full body bulk fill flowable composite resins when polished using the same protocols applied to conventional flowable composite resins.
Materials and Methods:
One conventional composite resin (Filtek Supreme Flowable) and three full body bulk fill flowable composite resins (Metafil Bulk Fill, Charisma Bulk Flow ONE, G-aenial BULK Injectable) were tested. Specimens were polished using three methods: Soflex™ Extra-thin, One Gloss midi, and One Gloss midi combined with Jiffy brush. Surface roughness (Sa) was measured using a confocal laser scanning microscope, and surface morphology was examined under a scanning electron microscope. Statistical analysis was performed using two-way ANOVA and Scheffé’s test.
Results:
No interaction was found between the composite resin type and polishing method. Metafil Bulk Fill showed the highest surface roughness, while specimens polished with Soflex™ Extra-thin showed the smoothest surfaces (P < 0.05).
Conclusion
The surface roughness of full body bulk fill composite resins varies depending on the resin type and polishing method. Therefore, understanding each product’s characteristics and selecting an appropriate polishing technique is essential for achieving a clinically acceptable surface finish and long-term success of the restoration.
7.A case of feline extramedullary plasma cell tumor with T cell infiltration
Jung-Hyun KIM ; Jiwoong YOON ; Sol-Ji CHOI ; Woo-Jin SONG ; Youngmin YUN ; Myung-Chul KIM
Korean Journal of Veterinary Research 2024;64(3):e25-
A 7-year-old castrated male Persian cat presented with a cutaneous mass and an increase in serum amyloid A concentration. Fine needle aspirates of the mass indicated lymphoma, which was also the top differential diagnosis on histopathologic examinations. Immunohistochemically, neoplastic cells tested negative for anti-CD3, PAX5, CD20, and c-Kit, but positive for MUM1, CD79α, and CD138, suggesting extramedullary plasmacytoma. There were tumor-infiltrating non-neoplastic CD3+ T and CD20+ B cells. Practitioners should be aware of feline plasmacytoma characterized by lymphoma-like cytologic and histologic features. The present study is valuable in providing the first clinical evidence that proves the immunogenicity of feline plasmacytoma.
8.Positive rate of canine pancreatic lipase immunoreactivity (SNAP cPL) in relationship with severity of clinical signs and concurrent disorders: a retrospective study
Jongjin PARK ; Solji CHOI ; YoungMin YUN ; Myung-Chul KIM ; Woo-Jin SONG
Korean Journal of Veterinary Research 2024;64(3):e27-
Acute pancreatitis (AP) is a common disorder characterized by the inflammation of the exocrine pancreas in dogs, and the severity of the clinical signs of pancreatitis varies greatly. Therefore, the diagnosis of pancreatitis is challenging. The canine pancreatic lipase immunoreactivity test (SNAP cPL; IDEXX Laboratories Inc., USA) is rapid and relatively accurate in diagnosing pancreatitis. The purpose of this study was to evaluate the positivity rate of the SNAP cPL test in dogs regarding the severity of gastrointestinal (GI) signs and concurrent diseases. Electronic medical records of dogs were reviewed. For retrospective classification, 80 dogs with GI signs who underwent the SNAP cPL test were enrolled. Additionally, concurrent diseases on the day of the SNAP cPL test were reviewed. A positive SNAP cPL test result was observed in 26 of the 80 dogs (32.5%) with GI signs. The severity of GI signs using a scoring system and the positivity rate of SNAP cPL were statistically related. Furthermore, dogs with concurrent chronic kidney disease had a significantly higher positivity rate of SNAP cPL than those without chronic kidney disease. This information might help clinicians to decide whether a SNAP cPL test is needed.
9.Clinical and cytologic finding of mesothelioma in situ with hemorrhagic malignant pleural effusion in a dog
Donghyun HAN ; Youngmin CHOI ; Dong-In JUNG
Journal of Biomedical and Translational Research 2024;25(4):221-231
A 17-year-old spayed female Shih Tzu dog, weighing 5.0 kg, presented with frequent coughing and respiratory distress. Blood tests revealed mild thrombocytosis, and thoracic ultra-sonography and radiography confirmed a significant amount of pleural effusion. However,the thoracic radiographs showed no radiopaque nodules or interstitial patterns indicative ofthoracic tumors. Thoracentesis was performed to relieve effusion-induced thoracic pressure, yielding a hemorrhagic serosanguinous pleural fluid. The cytological analysis of this fluid re-vealed mesothelial cells, supporting the clinical diagnosis of mesothelioma in situ. To address the patient’s clinical symptoms, an aggressive management approach was implemented withchest tube placement to address recurrent pleural effusion after initial thoracentesis. Duringtreatment, the patient exhibited stable health and adapted well to daily life. To the best of our knowledge, this is the first reported case of mesothelioma in situ with hemorrhagic malignant pleural effusion in South Korea. Using a chest tube as an aggressive treatment successfullyalleviated dyspnea symptoms and provided symptomatic relief in a patient with mesothelioma in situ.
10.A case of feline extramedullary plasma cell tumor with T cell infiltration
Jung-Hyun KIM ; Jiwoong YOON ; Sol-Ji CHOI ; Woo-Jin SONG ; Youngmin YUN ; Myung-Chul KIM
Korean Journal of Veterinary Research 2024;64(3):e25-
A 7-year-old castrated male Persian cat presented with a cutaneous mass and an increase in serum amyloid A concentration. Fine needle aspirates of the mass indicated lymphoma, which was also the top differential diagnosis on histopathologic examinations. Immunohistochemically, neoplastic cells tested negative for anti-CD3, PAX5, CD20, and c-Kit, but positive for MUM1, CD79α, and CD138, suggesting extramedullary plasmacytoma. There were tumor-infiltrating non-neoplastic CD3+ T and CD20+ B cells. Practitioners should be aware of feline plasmacytoma characterized by lymphoma-like cytologic and histologic features. The present study is valuable in providing the first clinical evidence that proves the immunogenicity of feline plasmacytoma.

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