1.Acute carbon monoxide poisoning in Shandong, China: an observational study
Lina ZHANG ; Di WU ; Mingyue XU ; Yonghui BIAN ; Youcun WANG ; Guangkai GAO ; Qing SUN
Chinese Medical Journal 2022;135(13):1539-1544
Background::Carbon monoxide (CO) poisoning remains a major cause of accidental injuries and multiple studies have indicated that CO is also associated with significantly severe or long-term toxicity to the central nervous system. Given that CO poisoning causes serious morbidity and mortality, a better understanding of epidemiological features and clinical characteristics of acute CO poisoning in China is crucial.Methods::We collected the clinical data of acute CO poisoning in patients between November 2019 and April 2020 across Shandong province, China and analyzed its characteristics focusing on the weekly amount and the severity of the confirmed cases.Results::A total number of 21,088 acute CO poisoning cases were diagnosed. The overall incidence of acute CO poisoning was approximately 0.021%. On severity rankings, 63% of confirmed cases ( n = 13,378) were mild, 27% (n = 5635) were moderate, and 10% ( n = 2075) were severe. Interestingly, the coastal cities had more confirmed cases than the inland/suburban areas in Shandong. Meanwhile, the number of confirmed cases was negatively correlated with the local mean daily temperature ( P = 0.0167). Conclusions::Mild acute CO poisoning cases accounted for the majority of all confirmed cases during the winter of 2019. In Shandong province, which is located in east China, residents of the coastal cities are more susceptible to CO poisoning than residents of inland cities.
2.Clinical analysis on the effectiveness of modified vaginal hysterectomy for the treatment of uterine prolapse in elderly women
Youcun JIN ; Yurong HUA ; Peipei WANG ; Qiangen CAI
Chinese Journal of Geriatrics 2021;40(9):1169-1172
Objective:To examine the clinical effectiveness of modified vaginal hysterectomy for the treatment elderly women with uterine prolapse.Methods:Eighty-two elderly patients with uterine prolapse treated in the Affiliated Hospital of Jiangnan University from January 2017 to August 2020 were selected as research subjects, who were randomly and double-blindly divided into the control group and the observation group, with 41 patients in each group.The control group was treated with traditional vaginal hysterectomy, while the observation group was treated with modified vaginal hysterectomy.Surgical parameters(operating time, intraoperative blood loss and length of hospital stay), total clinical effectiveness rates and the incidences of complications in the two groups were compared.Results:The total effectiveness rate of the observation group was higher than that of the control group(97.6% vs.78.0%, χ2=7.291; P<0.05). The operation time[(71.3±15.5)min vs.(122.7±22.2)min, t=7.379, P=0.008], intraoperative blood loss[(122.5±15.3)ml vs.(297.7±20.7)ml, t=9.820, P=0.000]and hospitalization time[(7.2±1.5)d vs.(10.0±2.9)d, t=7.164, P=0.014]of the observation group were lower than those of the control group.The incidence of complications in the observation group was lower than that in the control group(0.0% vs.14.6%, χ2=7.159, P<0.05). Conclusions:Modified vaginal hysterectomy for elderly patients with uterine prolapse can help improve the clinical effectiveness and reduce the operating time, postoperative length of hospital stay and the incidence of postoperative complications.
3.Clinical effect of Hyperbaric oxygen coupled with compound Shexiang injection on diffuse axon injury
Shujing WU ; Jinping XIAO ; Yan SUN ; Yonghui BIAN ; Youcun WANG
Chinese journal of nautical medicine and hyperbaric medicine 2016;23(2):104-106
Objective To observe the clinical effect of hyperbaric oxygen (HBO) coupled with compound Shexiang injection on the patients with diffuse axon injury(DAI).Methods Sixty-eight cases of DAI were randomly divided into the treatment group and the control group,each consisting of 34 cases.The treatment group was treated with HBO coupled with compound Shexiang injection,while the control group was only given Shexiang injection.The clinical prognosis of the patients in the 2 groups was evaluated 6 months after injury by using GOS scores,and the recovery rates of consciousness were compared between the 2 groups.Results The GCS scores of the treatment group were increased markedly,as compared with those of the control group,and the rate of consciousness for the treatment group was obviously superior to that of the control group.Statistical significance could be noted,when comparisons were made between the 2 groups(P < 0.05).Conclusions HBO coupled with compound Shexiang injection could arouse consciousness and prognosis of the patients with DAI.
4.Clinical effect of Hyperbaric oxygen coupled with compound Shexiang injection on diffuse axon injury
Shujing WU ; Jinping XIAO ; Yan SUN ; Yonghui BIAN ; Youcun WANG
Chinese journal of nautical medicine and hyperbaric medicine 2016;23(2):104-106
Objective To observe the clinical effect of hyperbaric oxygen (HBO) coupled with compound Shexiang injection on the patients with diffuse axon injury(DAI).Methods Sixty-eight cases of DAI were randomly divided into the treatment group and the control group,each consisting of 34 cases.The treatment group was treated with HBO coupled with compound Shexiang injection,while the control group was only given Shexiang injection.The clinical prognosis of the patients in the 2 groups was evaluated 6 months after injury by using GOS scores,and the recovery rates of consciousness were compared between the 2 groups.Results The GCS scores of the treatment group were increased markedly,as compared with those of the control group,and the rate of consciousness for the treatment group was obviously superior to that of the control group.Statistical significance could be noted,when comparisons were made between the 2 groups(P < 0.05).Conclusions HBO coupled with compound Shexiang injection could arouse consciousness and prognosis of the patients with DAI.
5.Effect of hyperbaric oxygen on atherosclerosis in apoE-knockout mice
Huilong SHAO ; Qingbao YANG ; Zhenzhen FAN ; Ping ZHONG ; Youcun WANG
Chinese journal of nautical medicine and hyperbaric medicine 2015;(3):192-195
Objective To study the effect of hyperbaric oxygen ( HBO) on the atherosclerosis ( AS) and the possible mechanism in apolipoprotein E ( apoE )-knockout mice by observing the variation of atherosclerotic plaque pathological morphology , blood lipid and related inflammatory cytokines .Methods Twenty-eight 8-week old apoE-knockout male mice were fed with western-diet for 8 weeks.Four mice were randomly sacrificed to collect aortas for Hematoxylin and Eosin ( HE ) staining , and the AS model was ascertained under microscopy .Then, the remaining 24 mice were randomly assigned into the ( HBO) group (n=12) and the normal control group (n=12).The animals in the HBO group were treated with HBO once a day for 30 days and the animals in the control group were left there without HBO treatment .The body mass of the mice were weighed both before and after termination of HBO treatment .The day after termination of HBO treatment, the mice were sacrificed for the detection of blood lipids and serum C-reactive protein (CRP). Histopathological features of aorta were defined by Hematoxylin and Eosin (HE) staining.Subsequently, the area ratio of plaque and lumen and the ratio of intimal and media areas were analyzed by the image processing software.Results Following HBO treatment, there were no significant differences in blood lipid levels , when comparisons were made between the HBO group and the control group (P>0.05), however, the level of serum CRP in the HBO group was significantly lower than that of the control group (P<0.05).The HE staining indicated that large quantities of atherosclerotic plaques in the aorta of the control group and intima were thickened , and the area ratio of plaque and lumen and the ratio of intimal area and media area was obviously larger than those of the animals in the HBO group ( P <0.05).Conclusions HBO could inhibit the development of atherosclerosis , which was not related to the modulation of blood lipid .The effect of HBO on anti-inflammation might be related to further progress of atherosclerosis .
6.Effect of hyperbaric oxygen on atherosclerosis in apoE-knockout mice
Huilong SHAO ; Qingbao YANG ; Zhenzhen FAN ; Ping ZHONG ; Youcun WANG
Chinese journal of nautical medicine and hyperbaric medicine 2015;(3):192-195
Objective To study the effect of hyperbaric oxygen ( HBO) on the atherosclerosis ( AS) and the possible mechanism in apolipoprotein E ( apoE )-knockout mice by observing the variation of atherosclerotic plaque pathological morphology , blood lipid and related inflammatory cytokines .Methods Twenty-eight 8-week old apoE-knockout male mice were fed with western-diet for 8 weeks.Four mice were randomly sacrificed to collect aortas for Hematoxylin and Eosin ( HE ) staining , and the AS model was ascertained under microscopy .Then, the remaining 24 mice were randomly assigned into the ( HBO) group (n=12) and the normal control group (n=12).The animals in the HBO group were treated with HBO once a day for 30 days and the animals in the control group were left there without HBO treatment .The body mass of the mice were weighed both before and after termination of HBO treatment .The day after termination of HBO treatment, the mice were sacrificed for the detection of blood lipids and serum C-reactive protein (CRP). Histopathological features of aorta were defined by Hematoxylin and Eosin (HE) staining.Subsequently, the area ratio of plaque and lumen and the ratio of intimal and media areas were analyzed by the image processing software.Results Following HBO treatment, there were no significant differences in blood lipid levels , when comparisons were made between the HBO group and the control group (P>0.05), however, the level of serum CRP in the HBO group was significantly lower than that of the control group (P<0.05).The HE staining indicated that large quantities of atherosclerotic plaques in the aorta of the control group and intima were thickened , and the area ratio of plaque and lumen and the ratio of intimal area and media area was obviously larger than those of the animals in the HBO group ( P <0.05).Conclusions HBO could inhibit the development of atherosclerosis , which was not related to the modulation of blood lipid .The effect of HBO on anti-inflammation might be related to further progress of atherosclerosis .
7.Technology about mining log files of No.1 Military Medical Project
Youcun ZHU ; Dan LUO ; Mei WANG
Chinese Medical Equipment Journal 2004;0(08):-
The Logminer utility has been provided by the latest Oracle 8i version.It can analyze archived log files and online log files.This paper introduces how to install and use this utility,especially how to make the use of the auditing function on key users and key data tables,as well as recover the hostility operation without the shutdown of database.
8.Realization of Laboratory Instrument Connection with Mscomm32 Control
Youcun ZHU ; Qingwei BAI ; Xiaorong YANG ; Mei WANG ; Dan LUO
Chinese Medical Equipment Journal 1993;0(06):-
Objective To gather laboratory results automatically.Methods An interface software was developed with Mscomm32 control and PowerBuilder.Result The results of laboratory instruments were input into LIS database automatically.Conclusion Hospital engineer can realize the connection of laboratory instruments with Mscomm32 control and PowerBuilder.
9.Backup and recovery of database in No.1 Military Medical Project based on RMAN
Youcun ZHU ; Dan LUO ; Mei WANG ; Xiaorong YANG
Chinese Medical Equipment Journal 1989;0(01):-
It is the foundation of HIS that the database system runs well.Therefore,the database administrator is required to recover it rapidly when the system is broken down.This paper introduces how to backup and recover database by using RMAN which ORACLE corporation recommends.It is more rapid and more reliable than traditional cool backup and online backup.

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