1.Revision of quality indicators for cervical cancer and trend analysis of existing indicators in Japan
Tamaki KAKUWA ; Ryoko RIKITAKE ; Satoru NAGASE ; Mikio MIKAMI ; Tsukasa BABA ; Masanori KANEUCHI ; Hideki TOKUNAGA ; Manabu SEINO ; Toshinari MURAMATSU ; Wataru YAMAGAMI ; Kazuhiro TAKEHARA ; Hitoshi NIIKURA ; Yasuyuki HIRASHIMA ; Kiyoshi YOSHINO ; Yuichi ICHINOSE ; Akira KAWATA ; Takahiro HIGASHI
Journal of Gynecologic Oncology 2025;36(5):e78-
Objective:
Cervical cancer rates in Japan (16.0/100,000) exceed the global average rate (11.3/100,000, according to the High/Very-High Human Development Index in 2020). This necessitates the evaluation of care quality and the quality indicators (QIs) for cervical cancer that were developed in 2013 to serve this purpose. This study updated these indicators using current evidence and consensus while longitudinally examining trends in practice patterns.
Methods:
The revision involved reviewing existing QIs and patterns of care indicators and incorporating new indicators using the modified Delphi method. Adherence to these indicators was assessed using a linked hospital-based cancer registry-based diagnostic procedure combination database covering approximately 70% of patients with cancer in Japan. The longitudinal trends of the existing indicators were evaluated using the linear probability model.
Results:
Seven new indicators were added to the existing twelve. Two of the new indicators mainly focused on early-stage surgical intervention, while one focused on advanced-stage bevacizumab combination therapy, with adherence rates of 81.7%, 0.8%, and 45.9%.Longitudinal analyses revealed significant improvements with the use of cisplatin in concurrent chemoradiotherapy for advanced-stage cervical cancer (+1%/year), oral anticancer agents as maintenance therapy after primary treatment for early-stage cervical cancer (−0.8%/ year), and hysterectomy for adenocarcinoma in situ in patients above 44 years old (−2%/year).
Conclusion
The QIs for cervical cancer in Japan have been revised based on 2022 evidence.The existing and new indicators should be continually evaluated to correspond to the latest knowledge. This will facilitate the standardization and promotion of bottom-up improvements in cervical cancer care.
2.What Do Young Cardiovascular Surgeons Think about Research ?
Hironobu SAKURAI ; Shun TANAKA ; Yuta KUWAHARA ; Satoshi HOSHINO ; Kunihiko YOSHINO ; Rihito TAMAKI ; Ayako KATAGIRI ; Keita HAYASHI ; Daiki HARADA ; Kenichiro TAKAHASHI
Japanese Journal of Cardiovascular Surgery 2024;53(2):2-U1-2-U5
Along with clinical practice and education, research is among the most important activities for medical doctors. The same is true in cardiovascular surgery: Young cardiovascular surgeons are expected to improve their surgical techniques and prioritize their clinical practice. However, their perspective on the role of research in their field of expertise is unknown. Therefore, we conducted a survey of and discussion with young cardiovascular surgeons to clarify their thoughts and concerns about performing research. Here we review and report the survey and discussion results.
3.Double Valve Replacement Using Manouguian Technique for Deteriorated Bioprosthetic Mitral Valve after Aortic and Mitral Valve Replacement
Yuichi NAKAMURA ; Manabu YAMASAKI ; Kohei ABE ; Kunihiko YOSHINO ; Rihito TAMAKI ; Hiroyasu MISUMI
Japanese Journal of Cardiovascular Surgery 2023;52(6):401-405
An 83-year-old woman (BSA 1.36 m2) who had undergone aortic valve replacement (Magna ease 19 mm), mitral valve replacement (Epic mitral 25 mm), tricuspid annuloplasty (De Vega technique), and pulmonary vein isolation eight years earlier was referred to our hospital due to her heart failure symptoms. Ultrasound cardiography revealed severe mitral regurgitation due to perforation of bioprosthetic valve, severe mitral valve stenosis (mean pressure gradient 7.8 mmHg) due to bioprosthetic deterioration, and subsequent pulmonary hypertension (mean pulmonary artery pressure 49 mmHg, tricuspid regurgitation pressure gradient 85.5 mmHg). We performed a redo aortic valve (Inspiris 23 mm) and mitral valve (Epic mitral 29 mm) replacement using the Manouguian technique. The postoperative course was uneventful and pulmonary hypertension improved (tricuspid regurgitation pressure gradient 39.6 mmHg).
4.Approach of Kampo Treatment for COVID-19 by Tablet-type Devices with Remote Communicating Function
Kazuyo TOHYAMA ; Masaki TOHYAMA ; Izumi YAMAKAWA ; Yoshino TAMAKI ; Hiroshi NAKAMURA
Kampo Medicine 2022;73(1):91-96
In order to avoid the risk of COVID-19 among our clinic staffs, remote medical care using tablet-type devices was conducted in our fever outpatient clinic. In about 5 months, there were 87 patients with COVID-19 diagnosed by PCR test. Among them, 24 patients (15 men and 9 women, average age 36.2 years) were treated with Kampo medicine. Four of 24 patients required hospitalization. All patients, including those hospitalized cases, improved their symptoms during the observation period. We believe that Kampo medicine is effective in the early treatment of COVID-19. In addition, we consider that remote medical care using tablet-type devices is one of the useful methods in the treatment of highly contagious infectious diseases.


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