1.Risk and protective factors associated with adolescent depression in Singapore: a systematic review.
Wei Sheng GOH ; Jun Hao Norman TAN ; Yang LUO ; Sok Hui NG ; Mohamed Sufyan Bin Mohamed SULAIMAN ; John Chee Meng WONG ; Victor Weng Keong LOH
Singapore medical journal 2025;66(1):2-14
INTRODUCTION:
Adolescent depression is prevalent, and teen suicide rates are on the rise locally. A systemic review to understand associated risk and protective factors is important to strengthen measures for the prevention and early detection of adolescent depression and suicide in Singapore. This systematic review aims to identify the factors associated with adolescent depression in Singapore.
METHODS:
A systematic search on the following databases was performed on 21 May 2020: PubMed, EMBASE and PsycINFO. Full texts were reviewed for eligibility, and the included studies were appraised for quality using the Newcastle Ottawa Scale. Narrative synthesis of the finalised articles was performed through thematic analysis.
RESULTS:
In total, eight studies were included in this review. The four factors associated with adolescent depression identified were: (1) sociodemographic factors (gender, ethnicity); (2) psychological factors, including childhood maltreatment exposure and psychological constructs (hope, optimism); (3) coexisting chronic medical conditions (asthma); and (4) lifestyle factors (sleep inadequacy, excessive internet use and pathological gaming).
CONCLUSION
The identified factors were largely similar to those reported in the global literature, except for sleep inadequacy along with conspicuously absent factors such as academic stress and strict parenting, which should prompt further research in these areas. Further research should focus on current and prospective interventions to improve mental health literacy, targeting sleep duration, internet use and gaming, and mitigating the risk of depression in patients with chronic disease in the primary care and community setting.
Humans
;
Singapore/epidemiology*
;
Adolescent
;
Risk Factors
;
Depression/etiology*
;
Protective Factors
;
Male
;
Female
;
Life Style
;
Suicide
2.Utilising a COM-B framework to modify antibiotic prescription behaviours following third molar surgeries.
Chee Weng YONG ; Ruth CHOE ; Sarah Kho Xian CHUA ; Jing Li LUM ; Wendy Chia-Wei WANG
Annals of the Academy of Medicine, Singapore 2025;54(6):340-349
INTRODUCTION:
Antimicrobial resistance (AMR) poses a critical global health threat, with millions of deaths attributed to it annually. Antibiotic stewardship to combat AMR is the responsibility of all healthcare professionals. Despite evidence suggesting that it is unnecessary, dentists routinely prescribe prophylactic antibiotics following third molar (3M) surgeries.
METHOD:
This mixed-methods study examined the behavioural barriers influencing antibiotic prescribing practices within the Division of Oral and Maxillofacial Surgery at the National University Centre for Oral Health Singapore. This study used the capability, opportunity and motivation for behavioural change or COM-B framework to implement interventions targeting the behavioural barriers.
RESULTS:
Pre- and post-intervention data over 6 months showed a significant reduction in antibiotic prescriptions from 84.45% to 20.89%, following the implementation of COM-B strategies (P<0.001). Qualitative feedback from focus group discussions highlighted a positive shift in clinicians' attitudes towards antibiotic reduction, acknowledging the minimal infection risk associated with non-prescribing practices. Notably, complication rates remained stable throughout the study period, indicating no adverse effects from reduced antibiotic usage.
CONCLUSION
These findings demonstrated that the COM-B model can be successfully applied to modify deeply ingrained prescription habits, and underscored the effectiveness of a structured behavioural change intervention in enhancing compliance with antibiotic stewardship guidelines. The study advocates continuation of initiatives to sustain this positive trend and mitigate AMR in clinical practice.
Humans
;
Molar, Third/surgery*
;
Anti-Bacterial Agents/therapeutic use*
;
Singapore
;
Antimicrobial Stewardship/methods*
;
Practice Patterns, Dentists'/statistics & numerical data*
;
Antibiotic Prophylaxis
;
Female
;
Attitude of Health Personnel
;
Male
;
Tooth Extraction
;
Adult
;
Focus Groups
;
Practice Patterns, Physicians'
3.A Comparison between Structural Allografts and Polyetheretherketone Interbody Spacers Used in Anterior Cervical Discectomy and Fusion: A Systematic Review and Meta-analysis
Francis Jia Yi FONG ; Chee Yit LIM ; Jun-Hao TAN ; Hwee Weng Dennis HEY
Asian Spine Journal 2024;18(1):124-136
Among interbody implants used during anterior cervical discectomy and fusion (ACDF), structural allografts and polyetheretherketone (PEEK) are the most used spacers. Currently, no consensus has been established regarding the superiority of either implant, with US surgeons preferring structural allografts, whereas UK surgeons preferring PEEK. The purpose of this systematic review (level of evidence, 4) was to compare postoperative and patient-reported outcomes between the use of structural allografts PEEK interbody spacers during ACDF. Five electronic databases (PubMed, Embase, Scopus, Web of Science, and Cochrane) were searched for articles comparing the usage of structural allograft and PEEK interbody spacers during ACDF procedures from inception to April 10, 2023. The searches were conducted using the keywords “Spine,” “Allograft,” and “PEEK” and were performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines. Subsequent quality and sensitivity analyses were performed on the included studies. Nine studies involving 1,074 patients were included. Compared with the PEEK group, the structural allograft group had comparable rates of postoperative pseudoarthrosis (p=0.58). However, when stratified according to the number of levels treated, the 3-level ACDF PEEK group was 3.45 times more likely to have postoperative pseudoarthrosis than the structural allograft group (p=0.01). Subsequent postoperative outcomes (rate of subsidence and change in the preoperative and postoperative segmental disc heights) were comparable between the PEEK and structural allograft groups. Patient-reported outcomes (Visual Analog Scale [VAS] of neck pain and Neck Disability Index [NDI]) were comparable. This study showed that for 3-level ACDFs, the use of structural allografts may confer higher fusion rates. However, VAS neck pain, NDI, and subsidence rates were comparable between structural allografts and PEEK cages. In addition, no significant difference in pseudoarthrosis rates was found between PEEK cages and structural allografts in patients undergoing 1- and 2-level ACDFs.
4.Medical emergencies in Dentistry:Practical tips in implementation
Yong Chee Weng ; Raymond C.W. Wong
Annals of Dentistry 2019;26(1):45-52
In a rapidly aging society, many patients will have multiple medical co-morbidities and on polypharmacy.
Dental patients rarely have medical emergencies during their treatment and it is because of this rarity, that theodd emergency that presents can overwhelm the dentist’s ability to cope despite their theoretical knowledge. The authors discuss how to adapt the clinic facilities for managing an emergency and provide an overview of management of common emergencies that dentists may encounter.

Result Analysis
Print
Save
E-mail