[Objective]To explore Professor XU Guangxing's experience in differentiating and treating gastric cancer based on the"Yangming Weihe(stomach closed)"theory.[Methods]Through clinical shadowing,organizing and analyzing medical cases,and studying relevant literature,combined with Professor XU Guangxing's understanding of gastric cancer,this paper summarizes his experience in differentiating and treating gastric cancer based on the"Yangming Weihe"theory from the perspectives of theoretical connotation,etiology,pathogenesis and medication strategies.A medical case is included for validation.[Results]The theory of"Yangming Weihe"originates from the opening-closing-pivot theory.The Yangming closing mechanism serves as a component of the ascending and descending movement of Qi in the human body.Together with the Taiyin opening mechanism and the Jueyin closing mechanism,it collectively regulates the physiological functions of the stomach.Professor XU Guangxing proposes that the etiology and pathogenesis of gastric cancer can be categorized into three patterns:dysfunction of the Yangming closing mechanism;impaired Taiyin-Yangming opening-closing coordination;dual dysfunction of the Jueyin-Yangming closing mechanisms.His therapeutic strategies focus on:clearing heat,moistening dryness and promoting descending with bitter flavors to unblock Yangming;strengthening the spleen and harmonizing the middle-Jiao to support the opening-closing mechanism;dispersing wind pathogens and consolidating dissipation to restore the dual closing mechanisms.The attached medical case involved a postoperative gastric cancer patient,diagnosed as dual Jueyin-Yangming closing mechanism failure according to the"Yangming Weihe"theory.The treatment protocol emphasized:clearing dryness,nourishing Yin and unblocking-tonifying Yangming;dispersing wind,astringing dissipation and consolidating-descending Jueyin.The herbal regimen achieved stable and positive outcomes.[Conclusion]Professor XU Guangxing's approach to treating gastric cancer based on the"Yangming weihe"theory is characterized by unique insights into the etiology and pathogenesis,distinctive features in syndrome differentiation and treatment,and notable clinical efficacy.This methodology merits further research and broader promotion.

[Objective]To explore the academic characteristics of SHI Fa's On Continuation of Simple Formulas,the backbone physician of Yongjia medical school,and enrich the research on the academic thought of Yongjia medical school.[Methods]By using the method of literature research,through the study of On Continuation of Simple Formulas and other works of Yongjia medical school,combined with modern related research literature,this paper analyzes and sorts out the background,compilation principles and academic characteristics of On Continuation of Simple Formulas,and verifies it with medical cases.[Results]SHI Fa inherited the academic thoughts of CHEN Yan,the founder of Yongjia medical school,and his great disciple WANG Shuo,and corrected the oversimplification of Simple Formulas,"There is no difference between deficiency,excess,cold and heat syndromes,and one party governs one disease".Starting from clinical application,he not only pursued simplicity,but also pursued practicality.He abided by the principle of syndrome differentiation and treatment,adhered to the principle of pulse first and combination of pulse and disease,emphasized the protection of stomach Qi and the treatment of three causes,and advocated familiarity with medicinal properties and medication according to syndrome.The attached medical cases fully verified the fallacy of WANG Shuo's"one party governs all the syndromes"and the correctness of the academic characteristics of syndrome differentiation and treatment and addition and subtraction with the syndrome.[Conclusion]On Continuation of Simple Formulas attaches importance to the academic characteristics of syndrome differentiation,combination of pulse and disease,careful medication and protection of stomach Qi,which enriches the academic thought of Yongjia medical school and promotes the inheritance and development of Yongjia medical school.It also has enlightening significance for today's clinical diagnosis and treatment.

[Objective]To explore Professor XU Guangxing's experience in differentiating and treating gastric cancer based on the"Yangming Weihe(stomach closed)"theory.[Methods]Through clinical shadowing,organizing and analyzing medical cases,and studying relevant literature,combined with Professor XU Guangxing's understanding of gastric cancer,this paper summarizes his experience in differentiating and treating gastric cancer based on the"Yangming Weihe"theory from the perspectives of theoretical connotation,etiology,pathogenesis and medication strategies.A medical case is included for validation.[Results]The theory of"Yangming Weihe"originates from the opening-closing-pivot theory.The Yangming closing mechanism serves as a component of the ascending and descending movement of Qi in the human body.Together with the Taiyin opening mechanism and the Jueyin closing mechanism,it collectively regulates the physiological functions of the stomach.Professor XU Guangxing proposes that the etiology and pathogenesis of gastric cancer can be categorized into three patterns:dysfunction of the Yangming closing mechanism;impaired Taiyin-Yangming opening-closing coordination;dual dysfunction of the Jueyin-Yangming closing mechanisms.His therapeutic strategies focus on:clearing heat,moistening dryness and promoting descending with bitter flavors to unblock Yangming;strengthening the spleen and harmonizing the middle-Jiao to support the opening-closing mechanism;dispersing wind pathogens and consolidating dissipation to restore the dual closing mechanisms.The attached medical case involved a postoperative gastric cancer patient,diagnosed as dual Jueyin-Yangming closing mechanism failure according to the"Yangming Weihe"theory.The treatment protocol emphasized:clearing dryness,nourishing Yin and unblocking-tonifying Yangming;dispersing wind,astringing dissipation and consolidating-descending Jueyin.The herbal regimen achieved stable and positive outcomes.[Conclusion]Professor XU Guangxing's approach to treating gastric cancer based on the"Yangming weihe"theory is characterized by unique insights into the etiology and pathogenesis,distinctive features in syndrome differentiation and treatment,and notable clinical efficacy.This methodology merits further research and broader promotion.

[Objective]To explore the academic characteristics of SHI Fa's On Continuation of Simple Formulas,the backbone physician of Yongjia medical school,and enrich the research on the academic thought of Yongjia medical school.[Methods]By using the method of literature research,through the study of On Continuation of Simple Formulas and other works of Yongjia medical school,combined with modern related research literature,this paper analyzes and sorts out the background,compilation principles and academic characteristics of On Continuation of Simple Formulas,and verifies it with medical cases.[Results]SHI Fa inherited the academic thoughts of CHEN Yan,the founder of Yongjia medical school,and his great disciple WANG Shuo,and corrected the oversimplification of Simple Formulas,"There is no difference between deficiency,excess,cold and heat syndromes,and one party governs one disease".Starting from clinical application,he not only pursued simplicity,but also pursued practicality.He abided by the principle of syndrome differentiation and treatment,adhered to the principle of pulse first and combination of pulse and disease,emphasized the protection of stomach Qi and the treatment of three causes,and advocated familiarity with medicinal properties and medication according to syndrome.The attached medical cases fully verified the fallacy of WANG Shuo's"one party governs all the syndromes"and the correctness of the academic characteristics of syndrome differentiation and treatment and addition and subtraction with the syndrome.[Conclusion]On Continuation of Simple Formulas attaches importance to the academic characteristics of syndrome differentiation,combination of pulse and disease,careful medication and protection of stomach Qi,which enriches the academic thought of Yongjia medical school and promotes the inheritance and development of Yongjia medical school.It also has enlightening significance for today's clinical diagnosis and treatment.

Objective·To explore the effects of hypertension and dyslipidemia on cognitive function in the elderly.Methods·A dynamic population cohort was established by using prospective cohort study methods.In 2019,a complete cohort was selected from residents aged 65 and above who voluntarily participated in a free physical examination program in a community in Shanghai,serving as the baseline cohort.In 2022,512 community-dwelling elderly aged 67 to 93 were randomly selected from the same community as the follow-up cohort for the study.The collected date included residents' health records,various physical examination measurements,and Mini-mental State Examination(MMSE)scale scores.Results·Of the 512 cases that were followed up,the valid sample size was reduced to 495 after data cleaning.According to the baseline and follow-up cognitive assessments and changes,the cases were categorized into three cognitive groups:the improvement group,the normal group,and the decline group.The prevalence of hypertension in the decline group was 43.14%higher than that in the improvement group and 24.39%higher than that in the normal group(66.67%in the decline group vs 23.53%in the improvement group,P=0.011;66.67%in the decline group vs 42.28%in the normal group,P=0.040).Total cholesterol(TC)in the improvement group was lower than that in the normal group[improvement group(4.38±1.04)mmol/L vs normal group(5.11±1.12)mmol/L,P=0.009].Additionally,TC in the decline group in 2022 was higher than that in 2019[paired difference(0.46±0.87)mmol/L,95%CI 0.08?0.84,P=0.021].LDL-Ch in the improvement group was lower than that in the normal group[improved group(2.51±0.92)mmol/L vs normal group(3.07±1.00)mmol/L,P=0.024],and their HDL-Ch in 2022 was higher than that in 2019[paired difference(0.16±0.20)mmol/L,95%CI 0.06?0.26,P=0.005].The results of multinomial Logistic regression showed:TC in the improved group was lower than that in the normal group[β=4.12,OR=61.64,95%CI 1.52?2494.07,P=0.029]and the decline group[β=5.88,OR=357.35,95%CI 4.54?28149.75,P=0.008];the TAG[β=1.85,OR=6.34,95%CI 1.05?38.43,P=0.045],LDL-Ch[β=5.61,OR=274.06,95%CI 3.65?20567.57,P=0.011],and hypertension[β=1.90,OR=6.69,95%CI 1.53?29.16,P=0.011]in the decline group were higher than those in the improvement group;the age of the decline group was greater than that of the normal group[β=0.08,OR=1.08,95%CI 1.00?1.16,P=0.041],and the education level was lower than that of the normal group[β=1.22,OR=3.39,95%CI 1.28?8.94,P=0.014].Conclusion·Low TC and LDL-Ch and high HDL-Ch are beneficial to cognitive improvement.Conversely,hypertension,high TC,high TAG,high LDL-Ch,low education level,and advanced ages are risk factors for cognitive decline.

Objective lo investigate the recovery of urinary function and related influencing factors in patients with stress urinary incontinence(SUI)after the tension-free vaginal tape procedure at the mid-urethra.Methods A total of 112 SUI patients who underwent the tension-free vaginal tape procedure at the mid-urethra in Beijing Rehabilitation Hospital Affiliated to Capital Medical University from October 2018 to October 2023 were selected as the research subjects.The postoperative urinary function recovery of all patients was recorded.According to the postoperative urinary function recovery time,patients with a recovery time of≤3 days were included in the rapid recovery group,and those with a recovery time of＞3 days were included in the non-rapid recovery group.Clinical data including age,body mass index,menopausal status,vaginal delivery history,number of deliveries,disease severity,comorbid hypertension,diabetes,history of pelvic organ prolapse,maximum urinary flow rate,postoperative urinary retention,preoperative bladder residual urine volume,maximum bladder volume,hemoglobin(Hb)level,white blood cell(WBC)count,red blood cell(RBC)count,and platelet(PLT)count of patients between the two groups were compared.Factors affecting the recovery of urinary function in SUI patients were analyzed by multivariate logistic regression.Results The recovery time of urinary function in 112 patients with SUI ranged from 1 to 15(4.10±0.78)days.Specifically,64 patients(57.14％)recovered within 3 days,and 48 patients(42.86％)recovered in more than 3 days.The proportions of patients with menopause,history of vaginal delivery,history of pelvic organ prolapse,and postoperative urinary retention in the non-rapid recovery group were significantly higher than those in the rapid recovery group,and the maximum urinary flow rate was significantly lower than that in the rapid recovery group(P＜0.01).There were no significant differences in age,body mass index,number of deliveries,preoperative bladder residual urine volume,maximum bladder volume,Hb level,WBC count,RBC count,PLT count,disease severity,proportion of patients with comorbid hypertension and proportion of patients with diabetes between the two groups(P＞0.05).Multivariate logistic regression analysis showed that menopause,history of vaginal delivery,history of pelvic organ prolapse,postoperative urinary retention and maximum urinary flow rate were influencing factors for the recovery of urinary function in SUI patients after surgery(P＜0.05).Conclusion The recovery of urinary function in SUI patients after a transvaginal tension-free vaginal tape procedure at mid-urethra is not ideal.Menopause,history of vaginal delivery,history of pelvic organ prolapse,postoperative urinary retention and maximum urinary flow rate are the influencing factors for the recovery of urinary function in SUI patients.

Academic buoyancy refers to the ability of students to successfully overcome typical, non-major academic setbacks and challenges encountered in daily school life. It can affect students' academic behaviors, academic achievements, and emotional experiences. This paper reviews academic buoyancy from four perspectives: its definition, measurement tools, effects, and intervention strategies. Additionally, it analyzes the applicability of introducing academic buoyancy to nursing students in China, with the aim of providing a new perspective to alleviate academic pressure and improve academic behaviors among nursing students.

Objective:To learn about the application of medical ethics review in scientific research and prevention of endemic diseases.Methods:The method of retrospective analysis was used, original articles on field epidemiological investigation and clinical medicines published by Chinese Journal of Epidemiology from 2017 to 2020 were collected. Examination of medical ethics in national, provincial and municipal fund programs and nonfund projects was carried out. Statistical analysis was performed using Cochran-Armitage trend test and Cochran-Mantel-Haenszel (CMH) test.Results:A total of 638 articles were collected from 2017 - 2020, with 36 excluded and 602 remaining. The proportion of papers published after medical ethics review over the past four years was 56.85% (83/146), 62.50% (105/168), 59.87% (94/157), and 60.31% (79/131), respectively. There was no statistically significant difference in trend testing ( Z = 0.41, P > 0.05). There was no statistically significant difference in the proportion of papers produced by academic works, on-site investigations, and clinical medicine programs among different years (χ 2 = 0.01, 1.31, 1.92, P > 0.05). The proportion of papers published that supported by various fund programs that had undergone medical ethics review over the past four years was 60.55% (66/109), 62.28%(71/114), 62.38% (63/101), and 60.22% (56/93), respectively. The trend test showed no statistically significant difference( Z = - 0.03, P > 0.05). There was no statistically significant difference in the proportion of papers published that supported by national level projects, provincial and ministerial level projects, and municipal level projects among different years (χ 2 = 0.06, 0.02, 0.19, P > 0.05). The difference in the trend test of the output papers of research projects approved by the higher-level ethics committee and marked with approval numbers over the past 4 years was statistically significant ( Z = 2.85, P < 0.01); the difference was statistically significant when compared across years (χ 2 = 8.13, P < 0.01); the proportion of papers increased from 8.22% (12/146) in 2017 to 18.08% (25/131) in 2020 (χ 2 = 7.04, P = 0.008). There was no statistically significant difference ( Z = - 0.53, P > 0.05) in the proportion of papers that expressed their consent in terms of informed consent over the past 4 years; There was no statistically significant difference in comparison between different years (χ 2 = 0.28, P > 0.05). Conclusions:Medical ethics review has been taken seriously by the majority of researchers and is widely used in endemic scientific research and prevention projects.

Objective:To revise the family resilience assessment scale (FRAS) in patients with stroke and to evaluate its psychometric properties and applicability.Methods:FRAS was authorized and translated into Chinese.The scale items were revised based on the interview results of 13 patients with stroke and 11 caregivers and the opinions of 20 experts in related fields.A convenience sampling method was used to sample neurology and neurosurgery inpatients from 2 tertiary hospitals in Hangzhou twice from June to November 2022, with 325 questionnaires (sample 1) distributed the first time for item analysis and exploratory factor analysis, and 285 questionnaires (sample 2) distributed the second time for confirmatory factor analysis, criterion validity and reliability test.Data analysis was conducted by SPSS 26.0 and AMOS 24.0.Results:The exploratory factor analysis extracted 6 common factors(family beliefs, family spirit, family connection, family resources, family communication, family collaboration) with 32 items.Confirmatory factor analysis showed that the model fit well( χ2/ df=2.67, RMSEA=0.025, CFI=0.98, GFI=0.90, IFI=0.98, RMR=0.031). The cronbach's α coefficient of the total scale was 0.96, and 0.82-0.92 for the dimensions.The 2-week retest reliability was 0.99.The total scale score was positively correlated with the validity scale (family resilience scale) ( r=0.882, P<0.001). Conclusion:The family resilience scale for patients with stroke has good reliability and validity and can be used to assess the family resilience of patients with stroke.

Objective:To analyze the comprehensive quality of the "Chinese Journal of Endemiology" and provide a basis for improving the influence of the journal.Methods:The iournal evaluation data of "Chinese Science and Technology Journal Citation Reports (Core Version)" (2013 - 2017 periodicals, hereinafter referred to as the journal citation report) as a statistical source, epidemiological and environmental medicine core journals as reference objects, an analysis of the academic influence of "Chinese Journal of Endemiology" within journals in the same field was carried out. The overall quality of the journal was evaluated through adopting the dynamic evaluation model of academic influence of sci-tech periodicals, combined with the total cited frequency, influencing factor, he cited rate, source of literature, immediacy index, international papers ratio, fund papers ratio of "Chinese Journal of Endemiology" in 2013 - 2017 edition of the journal citation report, and calculating the academic impact assessment score ( I), and 5-year growth rate in 2012 - 1016. Results:The impact factors of the "Chinese Journal of Endemiology" in 2012 - 2016 were 0.745, 1.243, 1.507, 1.390, and 1.221, respectively; ranked 4th, 3rd, 2nd, 2nd and 2nd in the same field medical core journals (24 kinds), respectively. The total citation frequencies were 1 167, 1 682, 1 164, 1 688, and 1 584, respectively; ranked 9th, 5th, 7th, 7th and 7th in the same field medical core journals (24 kinds), respectively; the comprehensive scores were 40.4, 45.8, 42.0, 42.4, and 41.5, respectively; ranked 5th, 7th, 6th, 7th and 7th in the same field medical core journals (24 kinds), respectively. The results of the dynamic evaluation model of academic influence showed that the I values of the "Chinese Journal of Endemiology" in 2012 - 2016 were 240 035.56, 377 602.24, 434 144.09, 612 260.69, and 529 411.90, respectively; and the 5-year growth rate was 0.21. Conclusion:The academic influence of the "Chinese Journal of Endemiology" is on the rise, and the comprehensive quality of the journal is constantly improving.