Objective:To systematically evaluate the impact of internet-based patient decision aid (PtDA) on decision-making for prenatal screening and diagnosis among pregnant women.Methods:Randomized controlled trials (RCTs) on the application of internet-based PtDA for prenatal screening and diagnosis among pregnant women were searched in PubMed, Embase, Web of Science, CINAHL, Cochrane Library, China National Knowledge Infrastructure, Wanfang Date, VIP, and China Biology Medicine disc. The search period was from inception to August 11, 2024. Two researchers independently screened the literature, extracted data, and assessed the quality of included studies. Meta-analysis was performed using RevMan 5.4 software.Results:A total of 10 studies involving 3 838 pregnant women were included. The meta-analysis showed that internet-based PtDA significantly reduced decision conflict ( P<0.05), improved decision knowledge ( P<0.01), and decreased decision anxiety ( P<0.05) among pregnant women but had no significant impact on decision regret ( P>0.05) . Conclusions:Internet-based PtDA effectively reduce decision conflict and anxiety while improving decision knowledge during prenatal screening and diagnostic decision-making. Future studies should focus on developing culturally appropriate decision aids tailored to the Chinese context and explore the enhanced role of nurses in prenatal screening counseling.

Objective:To systematically analyze the reasons for delayed medical consultation in cervical cancer patients, providing a reference basis for promoting timely medical consultation and early treatment for cervical cancer patients.Methods:A computer-based search was conducted across various databases, including China National Knowledge Infrastructure, Wanfang Data, VIP, China Biology Medicine disc, PubMed, Web of Science, Embase, CINAHL, and Cochrane Library, for qualitative studies on delayed medical consultation in cervical cancer patients. The search covered all available records up to June 30, 2024. The Joanna Briggs Institute centre for evidence-based health care qualitative research quality assessment criteria was used to assess the quality of the included studies, and an integrative synthesis method was applied to combine the findings.Results:A total of 11 studies were included, with 36 individual findings. These findings were grouped into 13 new categories. A total of three major synthesized results were identified: insufficient awareness of cervical cancer, barriers to medical consultation behavior, and the influence of social factors.Conclusions:Strengthening the promotion of cervical cancer health knowledge, providing psychosocial support for patients, and establishing robust social support systems are essential strategies to facilitate timely medical consultation and early treatment for cervical cancer patients.

Objective:To systematically evaluate and integrate qualitative research on the experiences of patients with premature ovarian insufficiency (POI) , so as to provide a basis for developing targeted interventions.Methods:The qualitative research on the experiences of patients with POI was electronically searched in Wanfang Data, VIP, China National Knowledge Infrastructure, China Biology Medicine disc, PubMed, Cochrane Library, Embase, CINAHL, and Web of Science. The search period was from database establishment to July 19, 2024. The included articles were evaluated with the quality evaluation criteria for qualitative research of the Joanna Briggs Institute Evidence-Based Health Care Center. Aggregative synthesis was used to integrate the literature.Results:A total of 11 articles were included. The 38 themes were distilled and summarized into 12 new categories, culminating in four integrated outcomes of unfamiliar bodies, psychological shock and calming, the double-edged sword of family and society, and hormone therapy.Conclusions:Patients with POI face multiple pressures from illness, psychology, family and society. Improving the experience of patients with POI requires a concerted effort by healthcare professionals, families, and even society.

Objective:To systematically evaluate the impact of internet-based patient decision aid (PtDA) on decision-making for prenatal screening and diagnosis among pregnant women.Methods:Randomized controlled trials (RCTs) on the application of internet-based PtDA for prenatal screening and diagnosis among pregnant women were searched in PubMed, Embase, Web of Science, CINAHL, Cochrane Library, China National Knowledge Infrastructure, Wanfang Date, VIP, and China Biology Medicine disc. The search period was from inception to August 11, 2024. Two researchers independently screened the literature, extracted data, and assessed the quality of included studies. Meta-analysis was performed using RevMan 5.4 software.Results:A total of 10 studies involving 3 838 pregnant women were included. The meta-analysis showed that internet-based PtDA significantly reduced decision conflict ( P<0.05), improved decision knowledge ( P<0.01), and decreased decision anxiety ( P<0.05) among pregnant women but had no significant impact on decision regret ( P>0.05) . Conclusions:Internet-based PtDA effectively reduce decision conflict and anxiety while improving decision knowledge during prenatal screening and diagnostic decision-making. Future studies should focus on developing culturally appropriate decision aids tailored to the Chinese context and explore the enhanced role of nurses in prenatal screening counseling.

Objective:To systematically analyze the reasons for delayed medical consultation in cervical cancer patients, providing a reference basis for promoting timely medical consultation and early treatment for cervical cancer patients.Methods:A computer-based search was conducted across various databases, including China National Knowledge Infrastructure, Wanfang Data, VIP, China Biology Medicine disc, PubMed, Web of Science, Embase, CINAHL, and Cochrane Library, for qualitative studies on delayed medical consultation in cervical cancer patients. The search covered all available records up to June 30, 2024. The Joanna Briggs Institute centre for evidence-based health care qualitative research quality assessment criteria was used to assess the quality of the included studies, and an integrative synthesis method was applied to combine the findings.Results:A total of 11 studies were included, with 36 individual findings. These findings were grouped into 13 new categories. A total of three major synthesized results were identified: insufficient awareness of cervical cancer, barriers to medical consultation behavior, and the influence of social factors.Conclusions:Strengthening the promotion of cervical cancer health knowledge, providing psychosocial support for patients, and establishing robust social support systems are essential strategies to facilitate timely medical consultation and early treatment for cervical cancer patients.

Objective:To systematically evaluate and integrate qualitative research on the experiences of patients with premature ovarian insufficiency (POI) , so as to provide a basis for developing targeted interventions.Methods:The qualitative research on the experiences of patients with POI was electronically searched in Wanfang Data, VIP, China National Knowledge Infrastructure, China Biology Medicine disc, PubMed, Cochrane Library, Embase, CINAHL, and Web of Science. The search period was from database establishment to July 19, 2024. The included articles were evaluated with the quality evaluation criteria for qualitative research of the Joanna Briggs Institute Evidence-Based Health Care Center. Aggregative synthesis was used to integrate the literature.Results:A total of 11 articles were included. The 38 themes were distilled and summarized into 12 new categories, culminating in four integrated outcomes of unfamiliar bodies, psychological shock and calming, the double-edged sword of family and society, and hormone therapy.Conclusions:Patients with POI face multiple pressures from illness, psychology, family and society. Improving the experience of patients with POI requires a concerted effort by healthcare professionals, families, and even society.

Objective:To assess the prevalence of dentinal hypersensitivity (DH) and related factors in urban adults in China.Methods:The study was designed as an observational, cross-sectional epidemiological study carried out in adults aged 18-69 years old in seven cities (Beijing, Shanghai, Wuhan, Chengdu, Xi′an, Guangzhou, and Harbin) of China. The study was conducted from March 2021 to May 2023. Patients were required to complete a questionnaire regarding the subjects′ socio-economic factors, dietary behavior, oral health behavior and personal antecedent factors. DH was clinically diagnosed by judging whether the tooth cold air stimulation provoked DH or not, and recorded by investigator pain rating Schiff score. Compare the findings of six cities (Harbin excluded) with a similar study conducted in 2008.Results:In total, 11 622 subjects from seven cities in China participated the study. Fifty two point two percent (6 072/11 622) of subjects reported DH in questionnaire, 36.7% (4 266/11 622) of subjects reported experiencing DH in response to cold air stimulation for at least one study tooth. Risk factors including age, sex, city, toothbrush method and acid reflux showed marked associations with DH ( P<0.05). The prevalence of DH of urban residents in six cities (Harbin excluded) was 33.7% (3 335/9 882), higher than that in 2008 [29.7%(2 354/7 939)]. Conclusions:Overall, DH was common among urban adults in China and the prevalence increased in recent years. Better understanding of DH and its associated factors should be considered in its prevention and management by dental professionals.

Objective To explore the differences in MRI signs between traumatic and non-traumatic rotator cuff tears and their correlation with the degree of rotator cuff tears.Methods A retrospective analysis was conducted on the clinical data and MRI man-ifestations of 82 patients in the trauma group and 80 patients in the non-trauma group with rotator cuff tears confirmed by arthroscopy.MRI indicators included 10 parameters:the degree of rotator cuff tear,tendon kinking-sign,tendon retraction,muscle edema,fatty degeneration,muscle atrophy,long head of the biceps tendon injury,acromion type,acromio-humeral distance(AHD),and lateral acro-mion angle(LAA).The clinical data and MRI indicators of the two groups were compared,and the correlation between MRI indica-tors and the degree of rotator cuff tears was analyzed.Results There were no significant difference in age and gender between the trauma group and the non-trauma group(P＞0.05),but the onset time of symptoms was significantly shorter in the trauma group compared to the non-trauma group(30 d vs 135 d,P＜0.001).Muscle edema,tendon kinking-sign,and long head of the biceps tendon injury were more common in the trauma group(P＜0.05),while fatty degeneration and type Ⅲ acromion were more common in the non-trauma group.The average AHD was smaller in the non-trauma group compared to the trauma group(P＜0.001).In addition,type Ⅲ acromion was more commonly seen in full-thickness rotator cuff tears,and AHD value was negatively correlated with the degree of rotator cuff tears(P＜0.05).Conclusion Muscle edema,tendon kinking-sign,and long head of the biceps tendon injury on MRI are highly suggestive of traumatic rotator cuff tears,while fatty degeneration,type Ⅲ acromion and smaller AHD indicate non-traumatic rotator cuff tears.Type Ⅲ acromion and decreased AHD increase the risk of full-thickness rotator cuff tears.

Objective:To evaluate the effects of different exercises on executive function, moter skills and core symptoms in children with attention deficit hyperactivity disorder (ADHD) using network Meta-analysis, and to provide evidence-based basis for the treatment of children with ADHD.Methods:The randomized controlled trails(RCTs)of exercises on children with ADHD were searched in Web of Science, PubMed, Cochrane Library, Embase, PsycINFO, CNKI, Wanfang Data, VIP and CBM databases.The retrieval time limit was from the establishment of each database to May 2023.The Cochrane quality review manual was used to evaluate the quality of the included literatures.Stata 17.0 software was used to perform network Meta-analysis.Results:Finally, twenty-four studies were enrolled including five types of exercise intervention, such as aerobic exercise, multicomponent exercise, exergaming, high intensity interval training (HIIT) and traditional low-to-moderate intensity exercise therapy (TRAD).The results of network Meta-analysis showed that: in terms of improving executive function(working memory, inhibitory control, and cognitive flexibility), motor skills and core symptoms of children with ADHD, the optimal exercise intervention was aerobic exercises (surface under the cumulative ranking were 78.9%, 73.0%, 88.7%, 77.9% and 69.9% respectively).Conclusion:Exercises can improve executive function, improve motor skills, and alleviate ADHD core symptoms.Aerobic exercise has a better effect on improving executive function, motor skills and core symptoms of ADHD children.

Objective     To investigate the relationship between miR-3187-5p in peripheral blood and pericardial drainage after coronary artery bypass grafting (CABG) and postoperative atrial fibrillation (POAF). Methods     Patients who underwent CABG in the Heart Center of Beijing Chao-Yang Hospital from March to May 2022 were enrolled. Peripheral blood and pericardial drainage were collected at 0 h after surgery (immediate time for patients to return to ICU from operating room) to detect miR-3187-5p, and perioperative confounding factors were also collected. The miR-3187-5p was measured by quantitative real-time PCR and its regulated target genes were analyzed by bioinformatics. Results     A total of 15 patients were enrolled, including 9 males and 6 females with an average age of 65.6±8.2 years. The incidence rate of POAF was 40.0%. miR-3187-5p in pericardial drainage at 0 h after surgery was an independent predictor for POAF. A total of 1 642 target genes of miR-3187-5p were predicted. GO function enrichment analysis and KEGG signal pathway enrichment analysis showed that target genes of miR-3187-5p were enriched in TGF-β, MAPK, Wnt and other classical collagen metabolic signal pathways, which might activate collagen metabolism by negatively regulating SMAD6 and other inhibitors of the pathways. Conclusion     This study is the first to find that miR-3187-5p in pericardial drainage at 0 h  after surgery is a potential, novel, and predictive factor for POAF, which may be related to the regulation of myocardial fibrosis signal pathways like TGF-β, MAPK and Wnt pathways, promoting the early collagen metabolism imbalance after CABG, increasing the collagen deposition in the atrium, and then promoting the early structural reconstruction after CABG and leading to the occurrence of POAF. The result provides a research basis for the accurate prediction and prevention of clinical POAF.