1.Analysis of Influencing Factors on TCM Syndromes of Chronic Gastritis from the Perspective of Five Circuits and Six Qi
Zhanbo YU ; Yingrong LAO ; Zhaoxi LIU ; Minran HE ; Danghan XU ; Lili WANG
Journal of Guangzhou University of Traditional Chinese Medicine 2025;42(11):2689-2696
Objective To explore the correlation between traditional Chinese medicine(TCM)syndromes of chronic gastritis and the indicators of five circuits and six qi,revealing the influence of different congenital qi endowments on TCM syndrome differentiation and providing evidence for individualized treatment.Methods Medical records meeting inclusion/exclusion criteria were collected from the Hospital Information System(HIS)of Rui Bao Street Community Health Service Center in Haizhu District,Guangzhou between January 20,2017 and January 20,2023.Data included age,birth date,and syndrome differentiation.Yearly circuit(Suiyun),celestial control-terrestrial effect(Sitian-Zaiqian)qi,three patterns of five circuits(Wuyun-Sanji),and syndrome patterns were statistically analyzed using Excel for database construction,with SPSS 23.0 for x2 tests and Logistic regression.Results(1)Among 1 882 chronic gastritis patients,spleen-stomach weakness(25.3%,477/1 882)was the most prevalent syndrome,followed by liver-stomach disharmony type,damp-heat in the spleen-stomach type,stomach-yin deficiency type,and stasis obstruction of stomach collateral type(x2=69.950,P=0.000).(2)Significant differences existed in Suiyun(Taijiao,Taigong,Taiyu,Taizhi,Shaogong,Taishang),Sitian-Zaiqian(Shaoyin-Yangming,Taiyin-Taiyang,Yangming-Shaoyin,Taiyang-Taiyin),and Wuyun-Sanji(excessive/insufficient earth/metal/water circuit)distributions among syndromes(P<0.05 or P<0.01).(3)For Suiyun-syndrome relationships:Birth in Taijiao/Shaogong years was the high-risk factor for developing chronic gastritis of liver-stomach disharmony type(P<0.01);Taishang years were associated with stomach yin deficiency type(P<0.05);Taijiao/Shaogong/Taiyu years were protective against damp-heat in the spleen-stomach type(P<0.05 or P<0.01).(4)For Sitian-Zaiqian-syndrome relationships:Jueyin-Shaoyang/Yangming-Shaoyin years linked to spleen-stomach weakness type(P<0.05);Shaoyang-Jueyin years were correlated with damp-heat in the spleen-stomach type(P<0.05).(5)For Wuyun-Sanji-syndrome relationships:Insufficient earth/water circuit years were associated with liver-stomach disharmony type(P<0.05 or P<0.01);excessive/balanced metal circuit years linked to stomach yin deficiency type(P<0.05 or P<0.01);insufficient metal circuit years were correlated with damp-heat in the spleen-stomach type(P<0.05).Conclusion TCM syndromes of chronic gastritis are influenced by environment-body interactions,disordered visceral function and yin-yang imbalance.Clinical treatment should integrate the varied indicators of five circuits and six qi variations for personalized regimens to improve symptoms and quality of life.
2.Clinical Observation on Modified Bushen Huoxie Decoction for the Treatment of Vascular Dementia
Xiangjiang TANG ; Yingrong LAO ; Zhimin YANG ; Peixin HUANG ; Xiaodong LUO
Journal of Guangzhou University of Traditional Chinese Medicine 2004;0(06):-
[ Objective ] To observe the therapeutic effect of Bushen Huoxie Decoction (mainly composed of Radix Rehmanniae Preparata, Fructus Corni, Rhizoma Dioscoreae, Carapax et Plastrum Testudinis, Radix Polygoni Multiflori, Fructus Lycii, Radix Morindae Officinalis, Herba Cistanches, Rhizoma Acori Tatarinowii, Radix Polygalae, etc. ) for the treatment of vascular dementia (VD) . [Methods] Eighty cases of VD were randomized into two groups by using random number table: group A ( n = 40) was treated with modified Bushen Huoxie Decoction and group B (n = 40) with duxil and nimodipine. After a 3-month treatment, the therapeutic effect of the two groups was evaluated, and mini-mental state examination (MMSE), activities of daily life (ADL) and blood rheology before and after treatment were observed. [Results] The total therapeutic effective rate was 80.0% in group A and 57.5% in group B, the difference being significant ( P

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