Artery of Percheron(AOP)embolization or occlusion is a rare cerebrovascular disease that can lead to bilateral thalamic infarction with or without involvement of the upper midbrain.Due to its clinical rarity,lack of typical signs of cerebral infarction,and the diversity of patient symptoms,AOP occlusion-induced cerebral infarction is often misdiagnosed or overlooked,which delays the treatment.This article reported a case of a patient who presented with impaired consciousness as the primary symptom and was initially diagnosed with acute top-of-the-basilar artery embolism related cerebral infarction and underwent emergency endovascular thrombectomy,while the emergency angiography revealed an AOP occlusion.This article also analyzed the clinical features,diagnostic challenges,and treatment strategies of AOP occlusion in combination with the literature,with the aim of providing a reference for clinicians in the diagnosis and treatment of such cases.

Artery of Percheron(AOP)embolization or occlusion is a rare cerebrovascular disease that can lead to bilateral thalamic infarction with or without involvement of the upper midbrain.Due to its clinical rarity,lack of typical signs of cerebral infarction,and the diversity of patient symptoms,AOP occlusion-induced cerebral infarction is often misdiagnosed or overlooked,which delays the treatment.This article reported a case of a patient who presented with impaired consciousness as the primary symptom and was initially diagnosed with acute top-of-the-basilar artery embolism related cerebral infarction and underwent emergency endovascular thrombectomy,while the emergency angiography revealed an AOP occlusion.This article also analyzed the clinical features,diagnostic challenges,and treatment strategies of AOP occlusion in combination with the literature,with the aim of providing a reference for clinicians in the diagnosis and treatment of such cases.