Objective: To conduct a scoping review on the types, construction methods and predictive performance of health literacy prediction models based on machine learning methods, so as to provide the reference for the improvement and application of such models. Methods: Publications on health literacy prediction models conducted using machine learning methods were retrieved from CNKI, Wanfang Data, VIP, PubMed and Web of Science from inception to May 1, 2024. The quality of literature was assessed using the Prediction Model Risk of Bias ASsessment Tool. Basic characteristics, modeling methods, data sources, missing value handling, predictors and predictive performance were reviewed. Results: A total of 524 publications were retrieved, and 22 publications between 2007 and 2024 were finally enrolled. Totally 48 health literacy prediction models were involved, and 25 had a high risk of bias (52.08%), with major issues focusing on missing value handling, predictor selection and model evaluation methods. Modeling methods included regression models, tree-based machine learning methods, support vector machines and neural network models. Predictors primarily encompassed factors at four aspects: individual, interpersonal, organizational and society/policy aspects, with age, educational level, economic status, health status and internet use appearing frequently. Internal validation was conducted in 14 publications, and external validation was conducted in 4 publications. Forty-two models reported the areas under the receiver operating characteristic curve, which ranged from 0.52 to 0.983, indicating good discrimination. Conclusion Health literacy prediction models based on machine learning methods perform well, but have deficiencies in risk of bias, data processing and validation.

The advancement of computers and data explosion have ushered in the third wave of artificial intelligence(AI). AI is an interdisciplinary field that encompasses new ideas, new theories, and new technologies, etc. AI has brought convenience to ophthalmology application and promoted its intelligent, precise, and minimally invasive development. At present, AI has been widely applied in various fields of ophthalmology, especially in oculoplastic surgery. AI has made rapid progress in image detection, facial recognition, etc., and its performance and accuracy have even surpassed humans in some aspects. This article reviews the relevant research and applications of AI in oculoplastic surgery, including ptosis, single eyelid, pouch, eyelid mass, and exophthalmos, and discusses the challenges and opportunities faced by AI in oculoplastic surgery, and provides prospects for its future development, aiming to provide new ideas for the development of AI in oculoplastic surgery.

Abstract Enhancing the health literacy of the entire population is a prerequisite for improving the health of the entire population, and since the health attitudes and behaviors formed during childhood and adolescence have a profound impact on the health patterns of adulthood, the enhancement of health literacy of children and adolescents is of particular importance. As the main place for children and adolescents to receive education, schools should better fulfil the function of education and promotion of health literacy. China has been carrying out the pilot and promotion of health promoting schools (HPS) since 1995, and is currently in the stage of comprehensive improvement of HPS construction. This paper introduces the background and characteristics of Health-Literate Schools (HeLit-Schools) in foreign countries and compares them with HPS in China, drawing on the advantages of HeLit-Schools to provide a new idea and a new way of thinking for the construction of HPS in China and for the practice of the "Healthy China Initiative".

Objective To analyze the growth and development status of children with severe β-thalassemia major (β-TM) in Bazhong area and its correlation with hemoglobin concentration (HGB) and serum ferritin (SF) level, and to provide a theoretical basis for the diagnosis and treatment of children with β-TM in Bazhong area. Methods A total of 292 children with β-TM admitted to Bazhong Central Hospital from January 2019 to December 2020 were selected. The Z-score method was used to evaluate the growth and development of the children. According to the growth and development of the children, they were divided into the normal group (normal growth and development, n=163) and delayed group (growth and development delay, n=129). Another 60 healthy children were selected as the control group. The levels of HGB, serum SF, free triiodothyronine (FT3), free tetraiodothyroxine (FT4), and thyroid stimulating hormone (TSH) were compared among the three groups of children, and clinical data such as age, sex and age of onset were collected from the case system. Univariate analysis and logistic regression were used to analyze the independent risk factors of growth and development delay in β-TM children. Pearson correlation was used to analyze the correlation between growth retardation and HGB and serum SF levels in β-TM children. Results The serum SF and TSH levels in the delayed group were significantly higher than those in the normal group and the control group, while the levels of HGB and serum FT4 were significantly lower than those in the normal group and control group (P<0.05). There were significant differences in age of onset, course of disease, age of primary blood transfusion, compliance with iron removal, compliance with blood transfusion treatment, hypothyroidism and abnormal glucose metabolism between the delayed group and the normal group (P<0.05). Logistic regression analysis showed that poor compliance, HGB<90 g/L, and SF>2000 ng/mL were risk factors for growth retardation in β-TM children (P<0.05). Pearson correlation analysis showed that HGB was negatively correlated with HAZ score of β-TM children (r=-0.452 , P<0.05), while SF was positively correlated with growth HAZ score of β-TM children (r=0.412 , P<0.05). Conclusion The children with β-TM in Bazhong area are often accompanied by slow growth and development, which is closely related to HGB and serum SF levels. Especially for children with poor compliance of iron removal therapy, HGB<90 g/L, and SF>2000 ng/mL, the height, weight, and HGB and serum SF levels should be monitored regularly.

The Chinese Society of Clinical Oncology (CSCO) issued the new version of the guidelines on diagnosis and treatment of NSCLC in April 2023.The new version updated the diagnostic and therapeutic strategy of rare oncogenic mutations, including ROS1 fusion, BRAF V600E mutation, NTRK fusion, MET exon 14 skipping mutation, RET fusion, and EGFR exon 20 insertion mutation, in NSCLC.This review will interpret the most important updates in the guidelines 2023 regarding the diagnosis as well as first-line and post-line therapies of these rare oncogenic mutations.

Objective:To explore whether the comprehensive scoring method of postoperative pain management quality can effectively evaluate the quality of postoperative pain management in hospitals or departments.Methods:Using the purposive sampling method and the convenient sampling method, a total of 9 Orthopedic Departments of 9 hospitals in Zhejiang Province and Jiangsu Province from January to May 2018 were selected as the research objects. According to whether it was a painless ward certified by the hospital, they were divided into the painless ward group (4 departments) and the non-painless ward group (5 departments). The postoperative pain management quality comprehensive scoring method, the weighted rank sum ratio method and the weighted TOPSIS method were used to calculate the scores and rankings of each department. The score differences of different groups were compared, and the correlation analysis of the ranking results of different evaluation methods was carried out.Results:The total score of the first-level index of pain management comprehensive scoring method and the scores of all dimensions in the painless ward were higher than those of the non-painless ward, and the differences were statistically significant (all P<0.05). The scores of environmental and materials, system/guidelines/procedures, pain assessment, analgesia treatment, and analgesic effect in the secondary indicators of pain management comprehensive scoring method in painless wards were higher than those of non-painless wards, and the differences were statistically significant (all P<0.05). The results of three methods for evaluating quality of postoperative pain management in the department were not all the same, but they were positively correlated. The correlation coefficients of postoperative pain management quality comprehensive scoring method, the weighted TOPSIS method and the weighted rank sum ratio method were 0.933 and 0.833 (all P< 0.01) . Conclusions:The comprehensive scoring method of postoperative pain management quality can effectively reflect the pros and cons of postoperative pain management quality in hospitals or departments.

Analyzing the influence of mixed emotional factors on false memory through brain function network is helpful to further explore the nature of brain memory. In this study, Deese-Roediger-Mc-Dermott (DRM) paradigm electroencephalogram (EEG) experiment was designed with mixed emotional memory materials, and different kinds of music were used to induce positive, calm and negative emotions of three groups of subjects. For the obtained false memory EEG signals, standardized low resolution brain electromagnetic tomography algorithm (sLORETA) was applied in the source localization, and then the functional network of cerebral cortex was built and analyzed. The results show that the positive group has the most false memories [(83.3 ± 6.8)%], the prefrontal lobe and left temporal lobe are activated, and the degree of activation and the density of brain network are significantly larger than those of the calm group and the negative group. In the calm group, the posterior prefrontal lobe and temporal lobe are activated, and the collectivization degree and the information transmission rate of brain network are larger than those of the positive and negative groups. The negative group has the least false memories [(73.3 ± 2.2)%], and the prefrontal lobe and right temporal lobe are activated. The brain network is the sparsest in the negative group, the degree of centralization is significantly larger than that of the calm group, but the collectivization degree and the information transmission rate of brain network are smaller than the positive group. The results show that the brain is stimulated by positive emotions, so more brain resources are used to memorize and associate words, which increases false memory. The activity of the brain is inhibited by negative emotions, which hinders the brain's memory and association of words and reduces false memory.
Electroencephalography ; Emotions ; Humans ; Memory ; Music ; Prefrontal Cortex

Objective:To construct a postoperative pain management quality evaluation index system so as to provide an effective tool for postoperative pain management quality by hospital.Methods:From August 2017 to December 2018, original indexes were built based on Donabedian theory and literature research method, and primary indexes were constructed by group discussion. Delphi method was used to two rounds of consultation among 15 postoperative pain management experts to set up the final indexes, and index weight was defined with the analytic hierarchy process.Results:The postoperative pain management quality evaluation index system included 3 first-level indexes, 8 second-level indexes and 32 third-level indexes. The weights of 3 first-level indexes (structure, process and outcome) were 0.2, 0.4 and 0.4 respectively. Top 3 combined weights of second-level included the antalgic effect (0.266 7) , pain evaluation and re-evaluation (0.160 0) , antalgic therapy (0.160 0) . Top 3 combined weights of third-level included the incidence of moderate-severe active pain (0.143 9) , incidence of moderate-severe rest pain (0.079 2) and the sufficient rate of antalgic health education (0.073 0) . The Kendall coefficient of concordance of two rounds of expert consultation were 0.21 and 0.25 with statistical differences ( P<0.01) . Conclusions:The postoperative pain management quality evaluation index system the has all-round, scientific and reasonable content and can reflect the characteristics of multi-link and multidisciplinary cooperation of postoperative pain management which is worthy of clinical promotion.

Objective: To evaluate the effect and implementation of auricular acupressure therapy (AAT) in the treatment of acute and chronic non-cancerous pain. Methods: Computer search China Knowledge Network, China Biomedical Literature Disc (CBM), Wanfang Database, Weip Chinese Science and Technology Journal Database, PubMed, Web of Science, EMbase, Ebsco, Cochrane databases, a randomized controlled trial of AAT in the treatment of acute and chronic non-cancerous pain was included. The main outcome of AAT treatment for pain was pain intensity and analgesic drug use. Results: Of the 29 studies included, 93.1% (27/29) indicated that AAT was effective in relieving pain and/or reducing the amount of analgesic drugs; 15 and 12 of them were for acute and chronic non-cancerous pain, respectively. In the positive study with specific information description, 100% (27/27) selected the acupoints of the nervous system, 70.4% (19/27) chose the acupoints corresponding to the pain site, and 92.6% (25/27) used the seeds of the king to retain the seeds. Bean material, 81.0% (17/21) was self-administered by adult patients after successful mission; 12/13 of acute pain studies in AAT lasted for 7 days, 8/11 of chronic non-cancer Sexual pain treatment ranged from 14-28 days; 12/25 of the study was pressed 3-4 times/d, and 36.0% (9/25) of the study lasted 2-5 minutes per test; 16/17 The study used "Deqi" as the appropriate standard for pressing. Conclusion The included studies have shown that AAT can effectively alleviate 88.2% (15/17) of acute pain and 100% (12/12) of chronic non-cancerous pain. AAT can be performed with auricular acupoints and pain points corresponding to auricular points. The seed is not kept as a pressed bean material, and the adult patient himself is pressed to take the patient′s "getting gas". The duration of AAT is related to the type of pain. Although there is no uniform data on the number of auricular compressions/d and the length of each compression, there is a certain tendency.

Radiation induced lung injury (RILI) is a serious complication in patients received thoracic radiotherapy. The main clinical symptom of RILI includes short of breath, low fever and cough, seriously affect the survival of patients. How to better prevent and treat RILI is an urgent problem. Target theory, cytokine theory, free radical theory, and vascular endothelial cell damage theory are the main mechanisms of RILI. Among them, reactive oxygen species (ROS) produced during radiotherapy can induce tissue damage throughout the course of RILI, and have a direct effect on both radiation pneumonitis and radiation-induced lung fibrosis. Anti-oxygen therapy including thiol compounds, antioxidant enzymes, and plant antioxidants have been applied in the prevention and treatment of RILI. This article reviews the research and application of antioxidant therapy in RILI.
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