Acute urinary retention(AUR)occurs frequently among astronauts on orbit.The current treatment is complex and easy to damage the urethra,which seriously affects the life and work of astronauts.In contrast,acupuncture,a traditional Chinese remedy,has shown promising results in managing urinary retention.However,the specific acupoints that could potentially prevent AUR remain uncertain due to the unique physiological conditions experienced by individuals in space compared to those on Earth.To address this gap,our research delved into the mechanisms of AUR and acupuncture within both traditional Chinese medicine and modern medical practices.We conducted a thorough literature review from Pubmed,Web of Science,CNKI,Wanfang database,VIP database and Chinese Medical Code database.A hierarchical evidence-scoring approach was utilized to analyze the included literatures,thus devised acupuncture protocols for the treatment of AUR.The outcomes of our study aim to establish a foundation for the application of acupuncture in managing AUR.

Objective To investigate whether transcutaneous electrical acupoint stimulation(TEAS)can improve the muscle strength,endurance and work efficiency of calf muscles in healthy young men,aiming to explore a new method for preventing and combating microgravity-induced muscle atrophy in space environments.Methods 40 healthy young men aged 18-35 years were randomly divided into a Control group(Pseudo Transcutaneous Electrical Acupoint Stimulation)and a Experimental group(Transcutaneous Electrical Acupoint Stimulation)in a 1∶1 ratio,with 20 participants in each group.In the Control group,the indicator light of the stimulator was covered,and the device was turned on,but the electrodes did not contact the skin,The device automatically turned offafter 3 seconds.In the Experimental group,the TEAS device was connected to the current and TEAS intervention was performed.The electrical stimulation waveform was a sperse-dense wave with a frequency of 4/20 Hz,and the intensity was determined by patient tolerance.The acupoints selected for electrical stimulation in both groups were bilateral Zusanli(ST36)、Liangqiu(ST34),Taixi(KI3),and Fuliu(KI7).Zusanli and Liangqiu were paired,and Taixi and Fuliu were paired.The intervention frequency was 30 min/time,1 time/day,6 days/week,for 2 weeks.The relative peak torque at 60°/s,relative peak torque at 180°/s,and average power at 180°/s of the bilateral calf muscles were measured using an isokinetic dynamometer at 0th,7th,and 14d day of the experiment.Results After 1 week of TEAS,compared with Control group,there were no significant changes in the relative peak torque at 60°/s,relative peak torque at 180°/s and average power at 180°/s of the bilateral anterior calf muscles in the Experimental group(all P>0.05);however,compared with Control group,the relative peak torque at 60°/s and the relative peak torque at 180°/s of the bilateral posterior calf muscles in the Experimental group were significantly increased(all P<0.05).After 2 weeks TEAS;compared with the Control group,there were no significant changes in the relative peak torque at 60°/s,relative peak torque at 180°/s and average power at 180°/s of the bilateral anterior calf muscles in the Experimental group(all P>0.05);however,the relative peak torque at 60°/s,relative peak torque at 180°/s,and average power at 180°/s of the bilateral posterior calf muscles were significantly increased in the Experimental group(all P<0.05).Conclusion TEAS of Zusanli,Liangqiu,Fuliu and Taixi acupoints on the lower limbs for 2 weeks can effectively improve the maximum muscle strength,endurance and work efficiency of the posterior calf muscles in healthy young men.

Astronauts are affected by the space environment,and there are health problems in many systems of the body,which seriously affect the on-orbit work efficiency and the health recovery after landing.Although measures have been taken,there are still deficiencies.Acupuncture can regulate the body in a multi-target,multi-level and multi-system way to protect the health of astronauts,which is an effective measure to protect the health problems of astronauts.But there is no acupoint group database for aerospace medical problems,which limits the application of acupuncture in space.The aim of this paper is to solve the possible aerospace medical problems of astronauts by acupuncture.Firstly,the acupuncture indications in aerospace medicine are determined through literature research,expert consultation and expert consensus,and then the evidence collection,evidence evaluation and evidence aggregation are carried out through the"stratified evidence evaluation method"for ancient literature,modern literature and expert experience.Finally,acupoint prescriptions were recommended based on the comprehensive score of acupoints,and acupuncture prescriptions for all acupuncture indications in aerospace medicine were integrated to form an acupoint group database,so as to contribute more Chinese wisdom and solutions to solve aerospace medicine problems.

Objective To study the effects of different drying processes on the effective constituents in Wen Codonopsis pilosula (WPP) Decoction Pieces; To develop the optimized producing and preparing integration process based on fresh WPP.MethodsFresh WPP in harvest period was prepared respectively as follows:① Fresh WPP was dried to different percentage (30%–100%) of original moisture contents of crude drugs at 80℃ in oven, then sliced and dried at 50℃ to obtain eight decoction pieces of WPP (XⅠYP1–8).② The fresh WPP was baked to 50% of water content of crude drug under different temperatures (50–120℃), respectively, then sliced and dried at 50℃ to obtain eight decoction pieces of WPP (XⅡYP1–8).③ Dried WPP was moistened, sliced and naturally dried, then were renamed as traditional decoction pieces. The contents of lobetyolin and atractylenolideⅢ was determined by HPLC. The phenol-sulfuric acid and colorimetric method were applied respectively to detect contents of polysaccharide and total flavonoids. The contents of aqueous and alcoholic extracts were determined simultaneously. Results The contents of alcoholic extracts (55.36%), aqueous extracts (54.91%) and atractylenolideⅢ (10.95 μg/g) in XⅠYP3 pieces were higher than other decoction pieces.Conclusion The optimized process was that fresh WPP was baked to water content of 50% at 80℃, then sliced and dried. Compared with conventional preparing methods,the integration process was time-saving and effort-saving. Meanwhile, the prepared pieces have higher content of active ingredients.

Objective To investigate the influence of two positions for measuring instrument adapter on the measurement of hand-transmitted vibration in grinding machine using the intraclass correlation coefficient (ICC) of reliability assessment index,and to provide a basis for studies on the measurement standard for handtransmitted vibration.Methods With reference to the measurement standard for hand-transmitted vibration ISO 5349 Mechanical vibration-Measurement and evaluation of human exposure to hand-transmitted vibration-Part 1:General requirements and Mechanical vibration-Measurement and evaluation of human exposure to handtransmitted vibration-Part 2:Practical guidance for measurement at the workplace,the domestic AWA5936 hand-transmitted vibration measuring instrument and SVAN-106 hand-transmitted vibration measuring instrument from Poland were used to measure hand-transmitted vibration in 3 workers for grinding machine in a foundry for 5 days continuously from September to October,2014,and Y-axis data were recorded and compared.Results In worker A,the "T"-shaped adapter had a significantly higher mean Y-axis accelerated speed effective value than the "O"-shaped adapter [4.34 m/s2 (95％CI 4.05-4.63) vs 2.32 m/s2 (95％CI 2.27～2.38),t=13.781,P＜0.01]-In workers B and C,AWA5936 "U"-shaped adapter (placed at the position of the handle of grinding machine) had lower degrees of data variation of 12.55％ and 15.77％,respectively,suggesting good data stability.The measurement results showed significant differences across different positions of adapter(P＜0.01) and between all adapters except "O"-shaped and line-shaped adapters (all P＜0.01),while the measurement results showed no significant differences between the"O"-shaped and line-shaped adapters (P＞0.01).The comparison of the measurement results of AWA5936 vibration measuring instrument with an "U"-shaped adapter and SVAN-106 vibration measuring instrument with an "S"-shaped adapter showed an ICC of ＞0.80 (ICC=0.82),while the comparison of the measurement results of AWA5936 vibration measuring instrument with an "O"-shaped adapter and SVAN-106 vibration measuring instrument showed an ICC of ＜0.40.Conclusion SVAN-106 vibration measuring instrument with an "S"-shaped adapter placed at the palm and AWA5936 vibration measuring instrument with an"U"-shaped adapter placed at the handle of grinding machine can give comparable measurement results with good reliability.

Objective To investigate the influence of two positions for measuring instrument adapter on the measurement of hand-transmitted vibration in grinding machine using the intraclass correlation coefficient (ICC) of reliability assessment index,and to provide a basis for studies on the measurement standard for handtransmitted vibration.Methods With reference to the measurement standard for hand-transmitted vibration ISO 5349 Mechanical vibration-Measurement and evaluation of human exposure to hand-transmitted vibration-Part 1:General requirements and Mechanical vibration-Measurement and evaluation of human exposure to handtransmitted vibration-Part 2:Practical guidance for measurement at the workplace,the domestic AWA5936 hand-transmitted vibration measuring instrument and SVAN-106 hand-transmitted vibration measuring instrument from Poland were used to measure hand-transmitted vibration in 3 workers for grinding machine in a foundry for 5 days continuously from September to October,2014,and Y-axis data were recorded and compared.Results In worker A,the "T"-shaped adapter had a significantly higher mean Y-axis accelerated speed effective value than the "O"-shaped adapter [4.34 m/s2 (95％CI 4.05-4.63) vs 2.32 m/s2 (95％CI 2.27～2.38),t=13.781,P＜0.01]-In workers B and C,AWA5936 "U"-shaped adapter (placed at the position of the handle of grinding machine) had lower degrees of data variation of 12.55％ and 15.77％,respectively,suggesting good data stability.The measurement results showed significant differences across different positions of adapter(P＜0.01) and between all adapters except "O"-shaped and line-shaped adapters (all P＜0.01),while the measurement results showed no significant differences between the"O"-shaped and line-shaped adapters (P＞0.01).The comparison of the measurement results of AWA5936 vibration measuring instrument with an "U"-shaped adapter and SVAN-106 vibration measuring instrument with an "S"-shaped adapter showed an ICC of ＞0.80 (ICC=0.82),while the comparison of the measurement results of AWA5936 vibration measuring instrument with an "O"-shaped adapter and SVAN-106 vibration measuring instrument showed an ICC of ＜0.40.Conclusion SVAN-106 vibration measuring instrument with an "S"-shaped adapter placed at the palm and AWA5936 vibration measuring instrument with an"U"-shaped adapter placed at the handle of grinding machine can give comparable measurement results with good reliability.

BACKGROUNDInfancy is a critical period of growth and physiological development, in which breast milk is the best source of nutrients. Compared to western countries, research on breast milk of Chinese population are limited. Thus, it is necessary to measure breast milk energy and macronutrient concentrations of healthy urban Chinese mothers at different lactation stages, to expand the database of milk composition of Chinese population, and to examine whether dietary or other maternal factors can affect the levels of macronutrients in breast milk.

METHODSBreast milk of full expression of one side breast from 436 urban Chinese lactating mothers at 5-11 days, 12-30 days, 31-60 days, 61-120 days, and 121-240 days postpartum was obtained at 9:00 a.m. to 11:00 a.m. Total energy, lactose, protein, and fat contents were measured. 24-hour dietary recall was surveyed, and maternal nutrient intakes were analyzed.

RESULTSMilk composition changed over the course of lactation and large individual variations were documented. The concentrations were 61.3 kcal/dl for total energy, 7.1 g/dl for lactose, 0.9 g/dl for protein, and 3.4 g/dl for fat in mature milk. Stage of lactation was a strong factor affecting milk composition. Minimal evidence was found for associations between maternal current dietary intake and milk macronutrient concentration, consistently with prior research. Maternal body mass index (BMI) was positively associated with milk fat content, to a greater extent than did dietary intake. All other maternal characteristics were not significant for milk composition.

CONCLUSIONThese findings suggest that milk composition is generally weakly associated with maternal factors except for stage of lactation, and is likely to be more susceptible to long-term maternal nutritional status than short-term dietary fluctuation.

Adolescent ; Adult ; Body Mass Index ; Female ; Humans ; Lactation ; physiology ; Middle Aged ; Milk, Human ; chemistry ; Mothers ; Young Adult

Objective:To study short-term effects of PM10(particulate matter of aerodynamic diameter

Objective:To evaluate construct validity of China residents health literacy questionnaire and explore the application of confirmative factor analysis(CFA)in health literacy measurements.Methods:CFA was performed on dimension of basic healthy skills in the questionnaire.Latent variable scores and comprehensive score based on factor variance weight were calculated.Comparison among the latent variable scores,comprehensive scores and proportion of knowing was conducted via GLM or Logistic model.Results:Two factors named general capacity and emergency capacity were well fitted(?2=12.12,P=0.356,IFI=0.998,TLI=0.996,RMSEA=0.007).According to comprehensive score the sample qualification rate of basic health literacy was 38.5%(785/2 040),much similar to 38.2%(780/2 040)which is calculated by original item scores.Latent variable score or comprehensive score has more statistical power than that of proportion of knowing in multivariate analysis.Conclusion:CFA is a useful tool and valuable for applying in the field of health literacy measurement and analysis.