1.Perioperative emergency laparotomy pathway for patients undergoing emergency laparotomy: A propensity score matched study.
Joel Wen Liang LAU ; Janardhan BALIGA ; Faheem KHAN ; Ying Xin TEO ; Jonathan Ming Jie YEO ; Vincent Zhiwei YEOW ; Christine Xia WU ; Stephanie TEO ; Tracy Jia Hui GOH ; Philip IAU
Annals of the Academy of Medicine, Singapore 2024;53(12):713-723
INTRODUCTION:
Emergency laparotomy (EL) is associated with high morbidity and mortality, often exceeding 10%. This study evaluated the impact of the EMergency Laparotomy Audit (EMLA) interdisciplinary perioperative pathway on patient outcomes, hospital costs and length of stay (LOS) within a single centre.
METHOD:
A prospective cohort study was conducted from August 2020 to July 2023. The intervention team included specialist clinicians, hospital administrators and an in-hospital quality improvement team. Patients who underwent EL were divided into a pre-intervention control group (n=136) and a post-intervention group (n=293), and an 8-item bundle was implemented. Propensity scoring with a 1:1 matching method was utilised to reduce confounding and selection bias. The primary outcomes examined were LOS, hospitalis-ation costs and surgical morbidity, while secondary outcomes included 30-day mortality and adherence to the intervention protocol.
RESULTS:
The utilisation of the EMLA perioperative care bundle led to a significant reduction in surgical complications (34.8% to 20.6%, P<0.01), a decrease in LOS by 3.3 days (15.4 to 12.1 days, P=0.03) and lower hospitalisation costs (SGD 40,160 to 30,948, P=0.04). Compliance with key interventions also showed improvement. However, there was no difference in 30-day mortality.
CONCLUSION
This study offers insights on how surgical units can implement systemic perioperative changes to improve outcomes for patients undergoing emergency laparotomy.
Humans
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Laparotomy/methods*
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Propensity Score
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Female
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Male
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Prospective Studies
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Length of Stay/statistics & numerical data*
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Middle Aged
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Hospital Costs/statistics & numerical data*
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Postoperative Complications/epidemiology*
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Aged
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Emergencies
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Perioperative Care/methods*
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Critical Pathways
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Singapore
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Adult
2.Dietary intake of persons with depressive and psychotic disorders in Singapore.
Ying Ying LEE ; Jue Hua LAU ; Vanessa SEET ; Clare WHITTON ; P V ASHARANI ; Fiona Devi SIVA KUMAR ; Peizhi WANG ; Kumarasan ROYSTONN ; Laxman CETTY ; Wen Lin THE ; Swapna VERMA ; Yee Ming MOK ; Mythily SUBRAMANIAM
Annals of the Academy of Medicine, Singapore 2021;50(5):379-389
INTRODUCTION:
Nutritional psychiatry is an emerging field of study that investigates the role of diet and nutrition in mental health. Studies conducted in the general population have linked depressive symptoms with poor dietary patterns. The aim of this study was to characterise the dietary intake and analyse the dietary pattern using the Dietary Approach to Stop Hypertension (DASH) in a sample of psychiatric patients in a multiethnic Asian nation.
METHODS:
Participants were recruited from an outpatient clinic and an inpatient unit at the Institute of Mental Health in Singapore. Self-reported dietary habits of a sample of psychiatric patients (N=380) were analysed using DASH. To examine the variables associated with DASH scores, a linear regression was conducted with the full sample and sociodemographic variables.
RESULTS:
Persons with depressive disorders had a mean DASH score of 21.3 (±4.2), while persons with psychotic disorders had a mean DASH score of 21.2 (±4.9). Respondents who were older (B=1.94, 95% confidence interval [CI] 0.91-2.96,
CONCLUSION
Dietary patterns of persons with mental disorders were characterised. A host of sociodemographic factors, and not diagnosis of mental disorders, influenced the dietary quality of people with depressive and psychotic disorders. Clinicians treating psychiatric patients need to be aware of the nuanced reasons behind poor dietary choices and provide targeted psychoeducation to specific subgroups within the patient population.
3.Predictors of General Functioning and Correlates of Quality of Life: A Cross-Sectional Study among Psychiatric Outpatients.
Louisa PICCO ; Ying Wen LAU ; Shirlene PANG ; Anitha JEYAGURUNATHAN ; Janhavi A VAINGANKAR ; Edimansyah ABDIN ; Siow Ann CHONG ; Mythily SUBRAMANIAM
Annals of the Academy of Medicine, Singapore 2018;47(1):3-12
INTRODUCTIONFunctioning and quality of life (QOL) are negatively impacted as a result of mental illness. This study aimed to determine the: i) socio-demographic and clinical correlates of functioning and; ii) associations between functioning and QOL in a multiethnic sample of psychiatric outpatients.
MATERIALS AND METHODSThis was a cross-sectional study of outpatients receiving treatment from a tertiary psychiatric hospital. Functioning was assessed using the Global Assessment of Functioning (GAF) scale, while QOL was measured using the World Health Organization Quality of Life-BREF (WHOQOL-BREF) which comprises 4 domains: physical health, psychological health, social relationships and environment.
RESULTSVarious socio-demographic and clinical correlates were associated with functioning including employment and marital status, education and diagnosis. Depression was the only clinical characteristic which negatively correlated with functioning (= 0.035). Amongst the whole sample, multiple linear regressions revealed that functioning was positively associated with all 4 QOL domains (physical health [<0.001], psychological health [<0.001], social relationships [<0.001] and environment [<0.001]). Further analysis of each diagnostic group revealed that functioning was positively associated with all 4 QOL domains in the anxiety, depression and obsessive compulsive disorder subsamples, while in the schizophrenia subsample, functioning was only significantly associated with all environment domain.
CONCLUSIONFunctional impairments were associated with different socio-demographic and clinical characteristics, which should be addressed when planning tailored treatment and interventions. Given that functioning is significantly associated with QOL, it is crucial to regularly assess and monitor them (in addition to symptomatic outcomes and adopting a more holistic and biopsychosocial approach).

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