1.Feasibility of blood untargeted metabolomics in studying bladder function changes after spinal cord injury
Journal of Chongqing Medical University 2025;50(4):432-436
Traumatic spinal cord injury and bladder injury are both common surgical injuries.Metabolomics studies are the qualitative and quantitative analysis of all metabolites in a specific part of the organism and the science of the changing laws of these metabolites under external influences or disease conditions.The technology is mainly to analyze the metabolites in body fluids,cells,and tissues,and has become one of the important means for discovering biomarkers.The psychopathology of spinal cord injury is very complex.Blood metabolomics allows differential analysis of the substances in blood and has great value for exploring the disease process and mechanism.
2.Applying vector analysis to evaluate influence of ocular residual astigmatism on astigmatism correction by FS-LASIK
Yinbo ZHANG ; Huanjun KANG ; Xingguo DONG ; Yandong LIU
Recent Advances in Ophthalmology 2017;37(4):376-378
Objective To investigate the influence of ocular residual astigmatism (ORA) on the correction of astigmatism by FS-LASIK with vector analysis.Methods The records of 182 patients who had accept FS-LASIK between January,2016 and April,2016 were retrosepectively reviewed.The patients whose ORA ≥ refractive cylinder were assigned to high ocular residual astigmatism group (HORA group),ORA < refractive cylinder were assigned to low ocular residual astigmatism group (LORA group).All of the patients were followed 6 months or more.The visual acuity,error ratio and correction ratio were compared between HORA group and LORA group.Results The preoperative ORA of all patients was (0.61 ± 0.27) D,in which > 0.75 D were 58 cases (31.9%),and the HORA group was more than the LORA group (P < 0.05).At postoperative 6 months,there was no statistically significant difference in vision acuity between the HORA group (1.06 ± 0.15) and LORA group (1.08 ± 0.15) (t =0.97,P =0.35).There was statistically significant difference in the error ratio between the HORA group (58.11 ± 63.23) % and LORA group (26.12 ± 35.37) % (t =3.43,P < 0.05).There was statistically significant difference in the correction ratio between the HORA group (146.45 ± 86.63) % and LORA group (122.56 ± 36.31) % (t =2.81,P < 0.05).Conclusion The error ratio and correction ratio of astigmatic correction by FSLASIK is significantly higher in eyes with high ORA than in eyes with low ORA.Vector analysis should been carried out before the FS-LASIK.

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