Carpal tunnel syndrome is the most common peripheral nerve compression syndrome and a well-studied form of nerve entrapment syndrome as well. According to the etiology, the risk factors can be divided into individual risk factors and occupational risk factors. Individual risk factors include older age, gender (female), pregnancy, family history, hypothyroidism, diabetes, autoimmune diseases, advanced age, obesity, and wrist trauma, they are also associated with abnormal in the shapes and structures of the wist canal bones and tissues in individuals carpal tunnel bones and tissues. Occupational risk factors include the working posture of hands and wrists, work intensity, and tools, etc., that have attracted more and more attention from occupational disease prevention and control experts and management departments. In addition, the latest research also indicates that social psychosocial factors may also be an important factor in the occurrence and development of carpal tunnel syndrome. Therefore, it is necessary to actively carry out the prevention of occupational carpal tunnel syndrome, reduce the risk of the disease among workers and detect clinical symptoms as early as possible and intervene in time.

Antineoplastic drugs have clear health hazards to the human body. In recent years, the scale of use of antineoplastic drugs had continued to expand, and the occupational exposure risk of medical personnel had also increased, which had attracted widespread attention. Taking effective measures to prevent occupational exposure can protect the health of medical personnel. This article reviewed the laws, regulations, guidelines, and industry guidance documents on occupational exposure prevention and control of antineoplastic drugs issued by relevant departments and associations in China. It summarized the scientific management experience of antineoplastic drugs in China, with the aim of reducing the occupational exposure risk of antineoplastic drugs in the future, and assisting the healthy development of China's medical and health industry.

Objective:To analyze the situation of outpatient patients diagnosed with carpal tunnel syndrome (CTS) due to typical hand symptoms and evaluate the diagnostic factors of CTS patients.Methods:Through an electronic medical record information system, a retrospective analysis was conducted on the data of outpatient patients diagnosed with CTS with "numbness and pain in the hands" as the complaints from January 1, 2018 to December 31, 2022 in eight medical institutions including Peking University Third Hospital, Third People's Hospital of Guizhou Province, Zhejiang Provincial People's Hospital Bijie Hospital, then the demographic characteristics and diagnostic factors such as symptoms, signs, and auxiliary examinations were analyzed. Chi-square test was used to compare the differences in CTS diagnosis rates between different genders and age groups.Results:There were a total of 43105 outpatients with complaints of "numbness and pain in the hands" over the past 5 years, of whom 754 were diagnosed with CTS, with a diagnostic rate of 1.7%. The there were 166 males and 588 females diagnosed with CTS, and the diagnostic rate of female patients was significantly higher than that of male patients ( χ2=158.13, P<0.001). Among the CTS patients, the proportion of patients aged 45 to 60 was the highest (43.8%, 330/754), and there was a statistically significant difference in CTS diagnosis rates among patients of different age groups ( χ2=36.99, P<0.001). All CTS patients had varying degrees of hand symptoms, and some had definite abnormalities in auxiliary examinations such as physical examination, wrist ultrasound, MRI or neuroelectrophysiology. Conclusion:The diagnosis rate of CTS among outpatients presenting with complaints of "numbness and pain in the hands" is relatively low, and there are gender and age distribution differences. In addition to typical clinical symptoms, the diagnosis of CTS also requires objective evidence from physical examination and further auxiliary examinations.

Objective:To analyze the situation of outpatient patients diagnosed with carpal tunnel syndrome (CTS) due to typical hand symptoms and evaluate the diagnostic factors of CTS patients.Methods:Through an electronic medical record information system, a retrospective analysis was conducted on the data of outpatient patients diagnosed with CTS with "numbness and pain in the hands" as the complaints from January 1, 2018 to December 31, 2022 in eight medical institutions including Peking University Third Hospital, Third People's Hospital of Guizhou Province, Zhejiang Provincial People's Hospital Bijie Hospital, then the demographic characteristics and diagnostic factors such as symptoms, signs, and auxiliary examinations were analyzed. Chi-square test was used to compare the differences in CTS diagnosis rates between different genders and age groups.Results:There were a total of 43105 outpatients with complaints of "numbness and pain in the hands" over the past 5 years, of whom 754 were diagnosed with CTS, with a diagnostic rate of 1.7%. The there were 166 males and 588 females diagnosed with CTS, and the diagnostic rate of female patients was significantly higher than that of male patients ( χ2=158.13, P<0.001). Among the CTS patients, the proportion of patients aged 45 to 60 was the highest (43.8%, 330/754), and there was a statistically significant difference in CTS diagnosis rates among patients of different age groups ( χ2=36.99, P<0.001). All CTS patients had varying degrees of hand symptoms, and some had definite abnormalities in auxiliary examinations such as physical examination, wrist ultrasound, MRI or neuroelectrophysiology. Conclusion:The diagnosis rate of CTS among outpatients presenting with complaints of "numbness and pain in the hands" is relatively low, and there are gender and age distribution differences. In addition to typical clinical symptoms, the diagnosis of CTS also requires objective evidence from physical examination and further auxiliary examinations.

Carpal tunnel syndrome is the most common peripheral nerve compression syndrome and a well-studied form of nerve entrapment syndrome as well. According to the etiology, the risk factors can be divided into individual risk factors and occupational risk factors. Individual risk factors include older age, gender (female), pregnancy, family history, hypothyroidism, diabetes, autoimmune diseases, advanced age, obesity, and wrist trauma, they are also associated with abnormal in the shapes and structures of the wist canal bones and tissues in individuals carpal tunnel bones and tissues. Occupational risk factors include the working posture of hands and wrists, work intensity, and tools, etc., that have attracted more and more attention from occupational disease prevention and control experts and management departments. In addition, the latest research also indicates that social psychosocial factors may also be an important factor in the occurrence and development of carpal tunnel syndrome. Therefore, it is necessary to actively carry out the prevention of occupational carpal tunnel syndrome, reduce the risk of the disease among workers and detect clinical symptoms as early as possible and intervene in time.

Antineoplastic drugs have clear health hazards to the human body. In recent years, the scale of use of antineoplastic drugs had continued to expand, and the occupational exposure risk of medical personnel had also increased, which had attracted widespread attention. Taking effective measures to prevent occupational exposure can protect the health of medical personnel. This article reviewed the laws, regulations, guidelines, and industry guidance documents on occupational exposure prevention and control of antineoplastic drugs issued by relevant departments and associations in China. It summarized the scientific management experience of antineoplastic drugs in China, with the aim of reducing the occupational exposure risk of antineoplastic drugs in the future, and assisting the healthy development of China's medical and health industry.

Hazardous drugs represented by antineoplastic drugs have clear health hazards to occupational exposed populations, and this issue has received widespread attention all over the world in recent years. This article reviewed the laws, regulations, guidelines, and industry guidance documents for the prevention and control of occupational exposure to hazardous drugs issued by relevant departments and associations in the United States. It could provide a reference basis for the development of occupational environmental health standards and protection guidelines, with the aim of reducing the risk of occupational exposure to hazardous drugs and promoting the healthy development of healthcare services in China.

Objective:To explore the influencing factors of abnormal blood pressure and electrocardiogram (ECG) in occupational motor vehicle drivers.Methods:In January 2024, a cluster sampling method was used to study 606 occupational motor vehicle drivers from a transportation service enterprise in Beijing who completed occupational health examination in 2023 in Peking University Third Hospital as observation group and 596 non-occupational motor vehicle drivers as control group. The data of personal history, occupational history, blood pressure and ECG were collected, and the effects of occupational motor vehicle driving on hypertension and ECG were analyzed by multivariate logistic regression.Results:The age of workers in the observation group was (34.1±7.8) years old, and the length of service was (7.0±7.1) years. The age of the control group was (33.8±7.6) years old, and the working age was (7.7±6.5) years. There was no significant difference in age and length of service between the two groups ( t=0.62, -1.90, P=0.538, 0.057). Systolic blood pressure (133.0±14.7) mmHg, diastolic blood pressure (83.7±11.6) mmHg, hypertension detection rate of 33.0% (200/606), ECG abnormality detection rate of 39.9% (242/606). They were significantly higher than those in the control group [ (127.8±14.4) mmHg, (77.5±11.0) mmHg, 24.7% (147/596), 31.0% (185/596) ], and the differences were statistically significant ( P<0.05). Multivariate logistic regression analysis showed that occupational motor vehicle driving were risk factors for hypertension and abnormal ECG ( OR= 1.210, 1.578; 95% CI: 1.145-1.231, 1.237-2.012; P<0.001) . Conclusion:Occupational motor vehicle driving may increase the risk of hypertension and abnormal ECG in workers.

Hazardous drugs represented by antineoplastic drugs have clear health hazards to occupational exposed populations, and this issue has received widespread attention all over the world in recent years. This article reviewed the laws, regulations, guidelines, and industry guidance documents for the prevention and control of occupational exposure to hazardous drugs issued by relevant departments and associations in the United States. It could provide a reference basis for the development of occupational environmental health standards and protection guidelines, with the aim of reducing the risk of occupational exposure to hazardous drugs and promoting the healthy development of healthcare services in China.

Objective:To explore the influencing factors of abnormal blood pressure and electrocardiogram (ECG) in occupational motor vehicle drivers.Methods:In January 2024, a cluster sampling method was used to study 606 occupational motor vehicle drivers from a transportation service enterprise in Beijing who completed occupational health examination in 2023 in Peking University Third Hospital as observation group and 596 non-occupational motor vehicle drivers as control group. The data of personal history, occupational history, blood pressure and ECG were collected, and the effects of occupational motor vehicle driving on hypertension and ECG were analyzed by multivariate logistic regression.Results:The age of workers in the observation group was (34.1±7.8) years old, and the length of service was (7.0±7.1) years. The age of the control group was (33.8±7.6) years old, and the working age was (7.7±6.5) years. There was no significant difference in age and length of service between the two groups ( t=0.62, -1.90, P=0.538, 0.057). Systolic blood pressure (133.0±14.7) mmHg, diastolic blood pressure (83.7±11.6) mmHg, hypertension detection rate of 33.0% (200/606), ECG abnormality detection rate of 39.9% (242/606). They were significantly higher than those in the control group [ (127.8±14.4) mmHg, (77.5±11.0) mmHg, 24.7% (147/596), 31.0% (185/596) ], and the differences were statistically significant ( P<0.05). Multivariate logistic regression analysis showed that occupational motor vehicle driving were risk factors for hypertension and abnormal ECG ( OR= 1.210, 1.578; 95% CI: 1.145-1.231, 1.237-2.012; P<0.001) . Conclusion:Occupational motor vehicle driving may increase the risk of hypertension and abnormal ECG in workers.