Background: Total knee arthroplasty (TKA) is a common surgical procedure for patients with knee osteoarthritis. The patellar component plays a crucial role in knee biomechanics and can influence postoperative outcomes. This study aimed to investigate the relationship between radiological indices of patellar height and patient outcomes following TKA. Methods: A retrospective analysis was conducted on patients who underwent TKA for osteoarthritis. Radiographic measurements of patellar height, including the Insall-Salvati (IS) ratio, modified Blackburne-Peel (mBP) ratio, Caton-Deschamps ratio, and plateaupatellar angle (PPA), were obtained. Clinical outcomes were assessed using the Knee Society Score (KSS) and the Forgotten Joint Score-12 (FJS-12). Patient satisfaction and postoperative complications were also evaluated. Statistical analyses, including correlation analysis and multiple regression models, were performed to determine the association between radiological indices and patient outcomes. Results: The study included 330 cases that met the inclusion criteria. The analysis revealed significant correlations between different radiological indices of patellar height and patient outcomes. Lower postoperative PPA was correlated with worse KSS and range of motion scores. A decreased mBP ratio was associated with poorer FJS-12 responses and higher risks of dissatisfaction and patellar clunk or crepitus. Increased IS ratio was linked to a lower likelihood of incidental giving way of the knee. Advanced age was associated with reduced dissatisfaction and incidental giving way probabilities. Conclusions The findings of this study demonstrate that radiological indices of patellar height can predict patient outcomes following TKA. Assessing patellar height using various radiographic measurements provides valuable information for surgical planning and prognostic evaluation. Understanding the impact of patellar height on clinical outcomes can aid in optimizing TKA procedures and improving patient satisfaction. These findings emphasize the importance of considering patellar height as a predictive factor in TKA and highlight its potential role in guiding postoperative management and rehabilitation strategies.

Human skin self-repairs after trauma and surgery. During this process,the ability of the skin to achieve complete functional regeneration and avoid the formation of fibrosis (scarring) or chronic wounds is a key clinical concern. Studies on wound healing have suggested that several factors affect the process of wound healing,including race,age,wound site,and skin tension. However,the lack of systematic analysis of the complete definition and connotation of skin regeneration and fibrosis,as well as the key links in the regulatory network of wound healing,makes clinical application difficult. In this review,we discuss domestic and international literatures to formu-late the concept of skin regeneration and fibrosis,combine the latest research progress on the physiological and pathological processes of wound healing,and propose the key links of the regulatory network that can potentially affect the outcome of skin wound healing. There-fore,this review provides novel theoretical support for the study of wound healing and suggests innovative diagnostic and therapeutic strat-egies for clinical applications.

Human skin self-repairs after trauma and surgery. During this process,the ability of the skin to achieve complete functional regeneration and avoid the formation of fibrosis (scarring) or chronic wounds is a key clinical concern. Studies on wound healing have suggested that several factors affect the process of wound healing,including race,age,wound site,and skin tension. However,the lack of systematic analysis of the complete definition and connotation of skin regeneration and fibrosis,as well as the key links in the regulatory network of wound healing,makes clinical application difficult. In this review,we discuss domestic and international literatures to formu-late the concept of skin regeneration and fibrosis,combine the latest research progress on the physiological and pathological processes of wound healing,and propose the key links of the regulatory network that can potentially affect the outcome of skin wound healing. There-fore,this review provides novel theoretical support for the study of wound healing and suggests innovative diagnostic and therapeutic strat-egies for clinical applications.

Objective:To build the standardized knowledge base for hierarchical prevention care of neonatal hypoglycemia based on the risk prediction model of neonatal hypoglycemia, and to provide a decision-making basis for risk management to achieve predicitive neonatal hypoglycemia.Methods:Based on the best evidence summarized in strategies for the prevention and management of neonatal hypoglycemia published in 2020, evidence on the prevention and management of neonatal hypoglycemia was searched from BMJ Best Practice, UpToDate, Registered Nurses Association of Ontario, CNKI and other domestic and foreign databases and professional association websites. The retrieval period was from September 1, 2019 to August 31, 2022. The quality of newly included literature was evaluated, new evidence was extracted, and the best evidence in the prevention and management strategy of neonatal hypoglycemia published in 2020 was summarized and combined to form the first draft of the knowledge base. Experts in the field of neonatal nursing were invited to revise and discuss each item of the knowledge base, and the final draft of the knowledge base was formed. The final draft of the knowledge base was coded using the 2.5 version of the Clinical care classification system as the standardized language.Results:The risk prediction model of neonatal hypoglycemia was used as a grading tool, the final draft of the knowledge included 1 nursing diagnosis, 6 modules and 18 specific preventive nursing measures.Conclusions:The knowledge base for hierarchical prevention care of neonatal hypoglycemia based on risk prediction model can realize the prospective hierarchical nursing of neonatal hypoglycemia, which is scientific and practical, and is the basis to assist nurses to make clinical decisions.