1.Primary Renal Lymphoma Masquerading as Upper Tract Urothelial Carcinoma
Yeap Jing HUI ; Ahmad Faiz Najmuddin Mohd GHAZI ; Mohamed Ashraf Mohamed DAUD ; MD SALZIHAN MD SALLEH
Brunei International Medical Journal 2026;22():83-87
Case Report Open Access 15 Primary renal lymphoma without widespread nodal disease is a rare entity. Its diagnosis is challenging as it can mimic other more common renal malignancies such as renal cell carcinoma (RCC) or upper tract urothelial carcinoma (UTUC). We report a 65 -year-old male who presented a month history of bilateral flank pain. Initial computed tomography urography showed a soft tissue enhancing lesion with irregular margin in the left renal pelvis, extending distally to the left proximal ureter, suspicious of UTUC. He underwent laparoscopic left radical nephrectomy and bladder cuff excision. However, histopathology came back as a left renal in situ follicular B -cell neoplasm (ISFN). He was subsequently referred to haematology service for further management. This case report aims to raise awareness of ISFN and to consider renal lymphoma in a patient presenting with a renal mass. A high index of suspicion and judicious use of tissue biopsy can avoid unnecessary and potentially morbid surgical interventions
2.Primary Renal Lymphoma Masquerading as Upper Tract Urothelial Carcinoma
Yeap Jing HUI ; Ahmad Faiz Najmuddin Mohd GHAZI ; Mohamed Ashraf Mohamed DAUD ; MD SALZIHAN MD SALLEH
Brunei International Medical Journal 2026;22():83-87
Case Report Open Access 15 Primary renal lymphoma without widespread nodal disease is a rare entity. Its diagnosis is challenging as it can mimic other more common renal malignancies such as renal cell carcinoma (RCC) or upper tract urothelial carcinoma (UTUC). We report a 65 -year-old male who presented a month history of bilateral flank pain. Initial computed tomography urography showed a soft tissue enhancing lesion with irregular margin in the left renal pelvis, extending distally to the left proximal ureter, suspicious of UTUC. He underwent laparoscopic left radical nephrectomy and bladder cuff excision. However, histopathology came back as a left renal in situ follicular B -cell neoplasm (ISFN). He was subsequently referred to haematology service for further management. This case report aims to raise awareness of ISFN and to consider renal lymphoma in a patient presenting with a renal mass. A high index of suspicion and judicious use of tissue biopsy can avoid unnecessary and potentially morbid surgical interventions
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