Objective:To construct an assessment system for patents'values of medically technical achievements,and explore and analyze assessment method for patents'values,so as to provide support for transferring patents of the achievements of science and research of medical technique.Methods:Aimed at the problem that quantitative assessment of patents'value existed difficulty in transferring achievements of science and research at the field of medicine-engineer integration,a comprehensively assessment model of combining analytic hierarchy process(AHP)and the entropy weight method was adopted to construct assessment indicator system for patent's value from technical value,law value,market value and policy value,which can explore the contribution and application strategy of each indicator in evaluating the transfer of the achievement of medicine-engineer integration.The data of Patyee patent databases and China national intellectual property administration were retrieved during January 2015 and June 2025.The achievement's transfers of patents of Shanghai Ninth People's Hospital,Shanghai Jiaotong University in the database during January 2024 and June 2025 were used to conduct verification for the application of assessing patents'value.Results:The assessment system for patents'values included four first-level indicators(the technical value,law value,market value and policy value of patents)and 15 second-level indicators.During 2015 and 2021,the number of applying patents of the national public hospitals increased year by year,and it slightly decreased after reached to 79 608 patents in 2021.The number of invention patents maintained a trend of continuous growth in the last decade,and the ratio of invention patents to the total number of whole applied patents reached to 53.66%in 2024,which was the first time that the number of invention patents exceeded half of the number of the total of number of the patents.There was better consistency between AHP-entropy weight method and the amount of actually achievement transfer of patents in comprehensive assessing the top 12 patents with high value at ranking for patents'value degree of Shanghai Ninth People's Hospital,Shanghai Jiaotong University.Conclusion:The evaluation result of the assessment system for patents'value of medically technical achievement for the degree of patents'value is basically consistency with the actual transfer value of patents,and the degree of patents'value of database,which can effectively evaluate the value degree of the patents of medically technical achievement,and provide basis for decision-making of transferring patents in this technical field.

Objective:To construct an assessment system for patents'values of medically technical achievements,and explore and analyze assessment method for patents'values,so as to provide support for transferring patents of the achievements of science and research of medical technique.Methods:Aimed at the problem that quantitative assessment of patents'value existed difficulty in transferring achievements of science and research at the field of medicine-engineer integration,a comprehensively assessment model of combining analytic hierarchy process(AHP)and the entropy weight method was adopted to construct assessment indicator system for patent's value from technical value,law value,market value and policy value,which can explore the contribution and application strategy of each indicator in evaluating the transfer of the achievement of medicine-engineer integration.The data of Patyee patent databases and China national intellectual property administration were retrieved during January 2015 and June 2025.The achievement's transfers of patents of Shanghai Ninth People's Hospital,Shanghai Jiaotong University in the database during January 2024 and June 2025 were used to conduct verification for the application of assessing patents'value.Results:The assessment system for patents'values included four first-level indicators(the technical value,law value,market value and policy value of patents)and 15 second-level indicators.During 2015 and 2021,the number of applying patents of the national public hospitals increased year by year,and it slightly decreased after reached to 79 608 patents in 2021.The number of invention patents maintained a trend of continuous growth in the last decade,and the ratio of invention patents to the total number of whole applied patents reached to 53.66%in 2024,which was the first time that the number of invention patents exceeded half of the number of the total of number of the patents.There was better consistency between AHP-entropy weight method and the amount of actually achievement transfer of patents in comprehensive assessing the top 12 patents with high value at ranking for patents'value degree of Shanghai Ninth People's Hospital,Shanghai Jiaotong University.Conclusion:The evaluation result of the assessment system for patents'value of medically technical achievement for the degree of patents'value is basically consistency with the actual transfer value of patents,and the degree of patents'value of database,which can effectively evaluate the value degree of the patents of medically technical achievement,and provide basis for decision-making of transferring patents in this technical field.

Objective To investigate the clinical manifestation,neuroimaging characteristics and follow-up results of chorea associated with non-ketotic hyperglycemia (C-H-BG).Methods Clinical data of six patients with C-H-BG were analyzed retrospectively.Results The average age of the six patients (five female and one male) was 65.8±13.9 years,All patients had acute-subacute course.Patients presented with choreic movements involving facial muscles (n=6) and unilateral (n=5) or bilateral limbs (n=1).The average value of plasma glucose at admission was 9.21 ± 5.15 mmol/L.All patients had significantly elevated HbA1c (14.1 ±3.5％).The brain MRI T1 imaging from all patients showed hyperintensity in the basal ganglia,putamen,lenticular nucleus and caudate nucleus.SWI imaging revealed corresponding hypointensity signal in the basal ganglia in three patients.Two patients had severe stenosis of the MCA.Five patients were followed up for an average of 16.2 ±7.2 months.Three patients died.Conclusion The high T1 hypertense lesions in the basal ganglia are the mainly radiological feature of C-H-BG which may be accompanied by SWI hytointense signals in the basal ganglia.