The theory of constitution in traditional Chinese medicine （TCM） has emerged as a new discipline in recent years. Constitution plays a vital role in the onset，progression，transformation，and prognosis of diseases. At present，some clinical scholars have adopted a novel diagnostic and treatment model of "constitution differentiation-disease identification-syndrome differentiation"，in which constitution is regarded as a core element throughout the diagnostic and therapeutic process. Constitution is closely associated with etiology，onset，pathogenesis，syndrome differentiation，and treatment. Against this background，the construction of animal models based on constitution holds far-reaching significance for advancing clinical research. This paper focuses on the construction and evaluation of rodent models with Qi-deficiency constitution，aiming to explore how to further induce Qi-deficiency syndromes and related disease states on the basis of Qi-deficiency constitution models，thereby developing an integrated animal model that embodies the trinity of "constitution-disease-syndrome". The establishment of this model not only provides a solid experimental foundation for the development of new therapies and drugs in TCM targeting specific constitutions，diseases，and syndromes，but also greatly promotes the modernization and scientific advancement of TCM theory. By comprehensively applying multidisciplinary technologies and methods，the study evaluates the model's validity，reliability，and practicality，with the aim of opening new avenues for future research in TCM and promoting the development of the field.

The theory of constitution in traditional Chinese medicine （TCM） has emerged as a new discipline in recent years. Constitution plays a vital role in the onset，progression，transformation，and prognosis of diseases. At present，some clinical scholars have adopted a novel diagnostic and treatment model of "constitution differentiation-disease identification-syndrome differentiation"，in which constitution is regarded as a core element throughout the diagnostic and therapeutic process. Constitution is closely associated with etiology，onset，pathogenesis，syndrome differentiation，and treatment. Against this background，the construction of animal models based on constitution holds far-reaching significance for advancing clinical research. This paper focuses on the construction and evaluation of rodent models with Qi-deficiency constitution，aiming to explore how to further induce Qi-deficiency syndromes and related disease states on the basis of Qi-deficiency constitution models，thereby developing an integrated animal model that embodies the trinity of "constitution-disease-syndrome". The establishment of this model not only provides a solid experimental foundation for the development of new therapies and drugs in TCM targeting specific constitutions，diseases，and syndromes，but also greatly promotes the modernization and scientific advancement of TCM theory. By comprehensively applying multidisciplinary technologies and methods，the study evaluates the model's validity，reliability，and practicality，with the aim of opening new avenues for future research in TCM and promoting the development of the field.

OBJECTIVE: To analysis the relationship between nasal septal deviation and the bulbous type concha bullosa(CB). METHOD: Analysis the paranasal sinus coronal plane CT scans of 972 patients,observe the incidence of nasal septal deviation and bulbous type concha bullosa and classify them into upper septal deviation and lower septal deviation. Measure the septal deviation angle and transverse diameter of the bulbous type concha bullosa, and a nalysis the relationship between nasal septal deviation and the bulbous type concha bullosa. RESULT: The incidences of bulbous type concha bullosa was 17.03% of 182 patients with nasal septal deviation and was 14.05% of 790 patients without nasal septal deviation. There was no statistically difference between them(P > 0.05). The incidences of bulbous type concha bullosa were 33.33% and 9.02% of the patients with upper septal deviation and lower septal deviation, and the difference was statistical (P < 0.01). The mean of the septal deviation angle was 14.55 degrees +/- 3.61 degrees, and the transverse diameter of the bulbous type concha bullosa was (5.93 +/- 1.88) mm in 20 patients with upper septal deviation and CB. The mean of the septal deviation angle was 13.36 degrees +/- 2.42 degrees, and the transverse diameter of the bulbous type concha bullosa was (4.86 +/- 1.40) mm in 11 patients with lower septal deviation and CB. There was no statistically difference between the septal deviation angle and the transverse diameter of bulbous type concha bullosa (P > 0.05). CONCLUSION There was a significant relationship between upper nasal septal devia tion and bulbous type concha bullosa, especially finding bulbous type concha bullosa in concave sides of nasal sep turn. But there was no significant relationship between the septal deviation angle and the size of the bulbous type concha bullosa.
Adolescent ; Adult ; Aged ; Child ; Female ; Humans ; Male ; Middle Aged ; Nasal Septum ; abnormalities ; diagnostic imaging ; Tomography, X-Ray Computed ; Turbinates ; abnormalities ; diagnostic imaging ; Young Adult

OBJECTIVE: To retrospectively analyze the clinical characteristics of the benign paroxysmal positional vertigo (BPPV) secondary to the sudden deafness (SD) and to explore pathogenetic mechanism. METHOD: One hundred and seventy-eight cases of the SD in our department were retrospectively analyzed. They were all treated under the guidance of clinical guidelines. RESULT: (1) In all these patient's with SD, there were 31 cases with BPPV secondary to the SD. There were 26 cases of BPPV of posterior semicircular canal and 5 cases of BPPV of lateral BPPV semicircular canal. All patients with BPPV were diagnosed as the same ears as the SD, including 16 cases on left sides and 15 on right sides. (2) The interval between the onset of SD and BPPV was less than one week in 27 cases, between one week and one month in 3 cases, and between one and three months in 1 case. (3) All patients with BPPV secondary to the SD were cured with Epley maneuver or Barbecue roll maneuver. CONCLUSION The occurrence of BPPV may follow SD, and the major of BPPV secondary to the SD occurs in the posterior semicircular canal. The canalith repositioning is an effective therapy to the secondary BPPV.
Adult ; Aged ; Benign Paroxysmal Positional Vertigo ; Female ; Hearing Loss, Sudden ; complications ; diagnosis ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Vertigo ; diagnosis ; etiology ; Young Adult