1.The relationship between CT and MRI findings of thymus tumors and immunohistochemical expressions of Ki-67 and p63
Journal of Practical Radiology 2025;41(6):938-942
Objective To analyze the relationship between CT and MRI findings of thymus tumors and the expressions of Ki-67 and p63 in immunohistochemistry.Methods A total of 99 patients with thymus tumors were examined by CT and MRI to analyze the features of CT and MRI and the expressions of Ki-67 and p63 in cancer tissues of patients with different signs.Results The positive rates of Ki-67 and p63 in patients with thymus tumors were 61.62%and 64.65%,respectively.The positive rate of Ki-67 in patients with burr sign and lobulation sign was higher than that in those without signs(P<0.05).The positive rate of p63 in patients with fuzzy lesion boundaries and burr sign was higher than those with clear lesion boundaries and without burr sign(P<0.05).The positive rate of Ki-67 in patients with uneven enhancement signal and enlarged lymph nodes was higher than that in patients with uniform enhancement signal and without abnormal lymph nodes(P<0.05).The positive rate of p63 in patients with uneven enhancement signal and chest metastasis was higher than that in patients with uniform enhancement signal and without chest metastasis(P<0.05).By binary logistic regression analysis,burr sign,lobulation sign,uneven enhancement signal and enlarged lymph nodes could be the related factors of Ki-67 positive expression in thymus tumors patients.Burr sign,fuzzy lesion boundaries,uneven enhancement signal,and chest metastasis were correlated with p63 positive expression in patients with thymus tumors(P<0.05).Conclusion The CT and MRI signs of thymus tumors are correlated with the expressions of Ki-67 and p63 in tumor tissue.
2.The relationship between CT and MRI findings of thymus tumors and immunohistochemical expressions of Ki-67 and p63
Journal of Practical Radiology 2025;41(6):938-942
Objective To analyze the relationship between CT and MRI findings of thymus tumors and the expressions of Ki-67 and p63 in immunohistochemistry.Methods A total of 99 patients with thymus tumors were examined by CT and MRI to analyze the features of CT and MRI and the expressions of Ki-67 and p63 in cancer tissues of patients with different signs.Results The positive rates of Ki-67 and p63 in patients with thymus tumors were 61.62%and 64.65%,respectively.The positive rate of Ki-67 in patients with burr sign and lobulation sign was higher than that in those without signs(P<0.05).The positive rate of p63 in patients with fuzzy lesion boundaries and burr sign was higher than those with clear lesion boundaries and without burr sign(P<0.05).The positive rate of Ki-67 in patients with uneven enhancement signal and enlarged lymph nodes was higher than that in patients with uniform enhancement signal and without abnormal lymph nodes(P<0.05).The positive rate of p63 in patients with uneven enhancement signal and chest metastasis was higher than that in patients with uniform enhancement signal and without chest metastasis(P<0.05).By binary logistic regression analysis,burr sign,lobulation sign,uneven enhancement signal and enlarged lymph nodes could be the related factors of Ki-67 positive expression in thymus tumors patients.Burr sign,fuzzy lesion boundaries,uneven enhancement signal,and chest metastasis were correlated with p63 positive expression in patients with thymus tumors(P<0.05).Conclusion The CT and MRI signs of thymus tumors are correlated with the expressions of Ki-67 and p63 in tumor tissue.
3.Consistency study in the measurement of epicardial adipose tissue volume using non-ECG-gated CT and ECG-gated CT
Qingshan WU ; Yanman ZHANG ; Wen JIANG ; Lemin TANG
Journal of Practical Radiology 2014;(6):937-942
Objective To investigate the consistency in the measurement of epicardial adipose tissue (EAT)volume using non-ECG-gated CT and ECG-gated CT.Methods ECG-gated CT and non-ECG-gated CT examinations were obtained in 104 subjects. The ECG-gated group was outlined the epicardium by an associate chief physician with a hand-painted method,the CT value of quan-titative adipose tissue was ranged from -30 HU to -250 HU.The non-ECG-gated group was outlined the epicardium by two asso-ciate chief physicians,A and B;The two CT values were ranged from -20 HU to -250 HU and from -30 HU to -250 HU,re-spectively.The measurement results of two groups were compared for the analysis of the relationship between EAT volume and cor-onary atherosclerosis.Results After the employment of CT value ranging from -20 HU to -250 HU for non-ECG-gated group, the measurement result was well consistent with ECG-gated group.The measurement results obtained by two associate chief physi-cians using the same range of CT value were in a good consistency.The EAT volumes obtained by various measurements were all correlated to the occurrence of coronary atherosclerosis.Conclusion After adjusting the range of CT value,two methods were in a good consistency.Non-ECG-gated CT measurement of EAT volume is easy to operate,which has a better practical value.

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