Objective This study was performed to explore the association between oral Helicobacter pylori(HP)infection and oral lichen planus(OLP).Methods Some online electronic databases such as PubMed,Embase,Cochrane Library,CNKI,Wanfang and Chongqing VIP were searched for the eligible case control studies.The association between oral HP infection and OLP was esti-mated by the pooled odds ratios(OR)and 95% confidence intervals(95% CI).Statistical analyses were performed by using STA-TA11.0 software.Fixed or random effects model was used to calculate ORs and 95% CI according to heterogeneity.Results A total of 7 studies with 307 patients and 207 healthy controls were included in the current study.The results of meta-analysis showed the patients with OLP had a significantly higher prevalence of oral HP infection compared with the healthy population(OR=8.43, 95% CI:2.90-24.52,P<0.001).Conclusion This study suggested that HP may be a risk factor for OLP.These findings may guide new strategies for OLP therapy and prevention.However,due to the influence of the quality of the included literature,addi-tional high quality of studies with larger sample sizes are needed.

A 5 years old boy was referred to our department with complaints of a painless midline neck swelling. Clinical feature: there was a painless swelling above the middle of thyroid cartilage, it was about 2.0 cm x 0.5 cm, and it was soft. And its boundary was clear. The skin temperature is normal. B-mode ultrasound features: there is a cystic mass in the front of the neck, it is about 2.3 cm x 1.0 cm, and be apart from the skin is 0.3 cm. It is showed that another cystic mass behind this one, is about 1.9 cm x 0.7 cm. The borders are clear, and no blood flow signal is detected. The thyroid was not abnormal. Pathology results showed the wall of cyst and there were pectin in the cyst. Diagnosis: thyroglossal cyst of double cyst.
Child, Preschool ; Humans ; Male ; Thyroglossal Cyst ; pathology