The construction of National Regional Centers is a significant strategic deployment to promote the expansion of high-quality medical resources and a balanced regional layout.It introduces the performance of Peking University First Hospital in promoting the construction of National Regional Centre for women and children's hospital with the work mode of"geographical homogenization construction",summarizes effectiveness.It is believed that government support is the foundation,output hospital sinking is the key,and input hospital participation is the guarantee.

The construction of National Regional Centers is a significant strategic deployment to promote the expansion of high-quality medical resources and a balanced regional layout.It introduces the performance of Peking University First Hospital in promoting the construction of National Regional Centre for women and children's hospital with the work mode of"geographical homogenization construction",summarizes effectiveness.It is believed that government support is the foundation,output hospital sinking is the key,and input hospital participation is the guarantee.

The construction of National Regional Centers is a significant strategic deployment to promote the expansion of high-quality medical resources and a balanced regional layout.It introduces the performance of Peking University First Hospital in promoting the construction of National Regional Centre for women and children's hospital with the work mode of"geographical homogenization construction",summarizes effectiveness.It is believed that government support is the foundation,output hospital sinking is the key,and input hospital participation is the guarantee.

The construction of National Regional Centers is a significant strategic deployment to promote the expansion of high-quality medical resources and a balanced regional layout.It introduces the performance of Peking University First Hospital in promoting the construction of National Regional Centre for women and children's hospital with the work mode of"geographical homogenization construction",summarizes effectiveness.It is believed that government support is the foundation,output hospital sinking is the key,and input hospital participation is the guarantee.

The construction of National Regional Centers is a significant strategic deployment to promote the expansion of high-quality medical resources and a balanced regional layout.It introduces the performance of Peking University First Hospital in promoting the construction of National Regional Centre for women and children's hospital with the work mode of"geographical homogenization construction",summarizes effectiveness.It is believed that government support is the foundation,output hospital sinking is the key,and input hospital participation is the guarantee.

The construction of National Regional Centers is a significant strategic deployment to promote the expansion of high-quality medical resources and a balanced regional layout.It introduces the performance of Peking University First Hospital in promoting the construction of National Regional Centre for women and children's hospital with the work mode of"geographical homogenization construction",summarizes effectiveness.It is believed that government support is the foundation,output hospital sinking is the key,and input hospital participation is the guarantee.

The construction of National Regional Centers is a significant strategic deployment to promote the expansion of high-quality medical resources and a balanced regional layout.It introduces the performance of Peking University First Hospital in promoting the construction of National Regional Centre for women and children's hospital with the work mode of"geographical homogenization construction",summarizes effectiveness.It is believed that government support is the foundation,output hospital sinking is the key,and input hospital participation is the guarantee.

The construction of National Regional Centers is a significant strategic deployment to promote the expansion of high-quality medical resources and a balanced regional layout.It introduces the performance of Peking University First Hospital in promoting the construction of National Regional Centre for women and children's hospital with the work mode of"geographical homogenization construction",summarizes effectiveness.It is believed that government support is the foundation,output hospital sinking is the key,and input hospital participation is the guarantee.

Objective To explore the image quality improvement of portal vein computed tomography venography(CTV)using CE-Boost technique with low dose and low contrast media usage.Methods A total of 50 patients with suspected portal vein disorders who underwent abdominal non-contrast and biphasic contrast-enhanced CT scans using the Canon 320-row CT machine were retrospectively selected.Images of portal venous phase(PVP)were postprocessed with CE-Boost technique.The CT values of each area,standard deviation(SD)values of the paraspinal muscles,volume CT dose index(CTDIvol),and dose length product(DLP)before and after CE-Boost were measured and recorded.The signal-to-noise ratio(SNR),contrast-to-noise ratio(CNR),effective dose(ED)of each blood vessel before and after CE-Boost were calculated.Subjective image quality was analyzed by two senior radiologists using a five-point scale in a double-blinded method.Statistical analysis was performed using paired t-test and Wilcoxon test.Results The CT values of each area with CE-Boost images were significantly higher than those without CE-Boost images(P＜0.001).SNR and CNR of each blood vessel with CE-Boost images were significantly higher than those without CE-Boost images(P＜0.001).The subjective scores of both images were above 3 points,which met the requirements of clinical diagnosis with good consistency(Kappa=0.772,0.697).The median subjective scores of images with CE-Boost were 5(5,5),which were significantly higher than those without CE-Boost images 5(5,4),(P=0.002).CTDIvol,DLP and ED were(1.85±1.12)mGy,(94.66±44.68)mGy·cm and(1.42±0.67)mSv,respectively.Conclusion CE-Boost technique can significantly improve the image quality of portal vein CTV with low dose and low contrast media usage.

Objective:To analyze the clinical features of adult patients with extremely elevated erythrocyte sedimentation rate (ESR, ESR≥100 mm/1 h), so as improve the ability of clinicians to use erythrocyte sedimentation rate to assist in the diagnosis and treatment of diseases.Methods:A retrospective cohort study was conducted to examine the clinical data of patients with ESR ≥ 100 mm/1 h admitted to the First Affiliated Hospital of Kunming Medical University from January 1st 2019 to December 31st 2019. The age, gender, clinical diagnosis, first ESR level after admission, blood routine, liver function, renal function, coagulation function and C-reactive protein (CRP) within 24 hours after admission were collected. Patient cohorts were divided into youth group (18-65 years old), middle-aged group (66-79 years old) and elderly group (≥80 years old) according to the new standards of human age classification of World Health Organization (WHO) 2019. Patient cohorts were also divided into infectious disease group, hematological disease group, autoimmune disease group, renal failure group and others according to their respective clinical diagnosis. The distribution of extremely elevated ESR in each group, and the correlation between ESR and various laboratory indicators were analyzed.Results:① Among 429 patients with ESR≥ 100 mm/1 h, there were 236 males and 193 females. There was no significant difference in ESR levels between males and females [mm/1 h: 108.00 (103.00, 119.75) vs. 117.00 (105.50, 140.00), P = 0.234]. ② The age of 429 patients ranged from 18 to 98 years old, the average age was (53.70±18.70) years old. There were 310 cases in the youth group, 87 cases in the middle-aged group and 32 cases in the elderly group. The ESR level of the young group was significantly lower than that of the middle-aged group and the elderly group [mm/1 h: 108.00 (103.00, 120.00) vs. 119.00 (107.00, 140.00), 120.00 (110.25, 140.00), both P < 0.01]. ③ The main diagnoses associated with extremely elevated ESR were infectious diseases [157 cases (36.6%)], hematological system diseases [127 cases (29.6%)], autoimmune diseases [74 cases (17.2%)]. Pulmonary infection accounted for 58.0% (91/157) of infectious diseases. Hematopoietic stem cell diseases accounted for 45.7% (58/127), lymphocyte and plasma cell diseases accounted for [37.0% (47/127)] and erythrocyte diseases accounted for [11.0% (14/127)] of the hematological system diseases. Diffuse connective tissue diseases accounted for 75.7% (56/74) of autoimmune diseases. ④ Spearman correlation analysis showed that the extremely elevated ESR in all patients was significantly negatively correlated with the levels of red blood cell count (RBC), hemoglobin (HB) and hematocrit (HCT) (ρvalue was -0.395, -0.381 and -0.383, respectively, all P < 0.01), the ESR was significantly positively correlated with the level of fibrinogen (FIB; ρ= 0.345, P < 0.01). A total of 266 patients were tested for both ESR and CRP, and there was no significantly correlation between ESR and CRP level (ρ= -0.019, P = 0.756). Conclusions:The extremely elevated ESR was more common in pulmonary infections diseases, hematopoietic stem cell diseases, lymphocyte and plasma cell diseases, erythrocyte diseases and diffuse connective tissue diseases. The extremely elevated ESR was significantly correlated with the levels of RBC, HB, HCT and FIB.