This report summarized and analyzed the clinical data of 3 patients with food-borne botulism admitted to our department. One case was sporadic, while the other two involved family members living together. All patients initially presented with blurred vision, ptosis, and dysphagia, and the disease progressed rapidly. During the course of the disease, all three cases developed respiratory failure; one patient received non-invasive ventilatory support, whereas the other two required invasive ventilator assisted ventilation. The serum toxin tests of the 3 patients were all positive for botulinum toxin type A. Sporadic food-borne botulism shares similar early symptoms and signs to myasthenia gravis and Guillain-Barre syndrome, and requires careful differential diagnosis. Botulinum antitoxin serum is the only effective treatment, and empirical antitoxin administration can be initiated immediately upon suspicion of botulism. Early detection and timely specific treatment are critical for improving patient outcomes.

This report summarized and analyzed the clinical data of 3 patients with food-borne botulism admitted to our department. One case was sporadic, while the other two involved family members living together. All patients initially presented with blurred vision, ptosis, and dysphagia, and the disease progressed rapidly. During the course of the disease, all three cases developed respiratory failure; one patient received non-invasive ventilatory support, whereas the other two required invasive ventilator assisted ventilation. The serum toxin tests of the 3 patients were all positive for botulinum toxin type A. Sporadic food-borne botulism shares similar early symptoms and signs to myasthenia gravis and Guillain-Barre syndrome, and requires careful differential diagnosis. Botulinum antitoxin serum is the only effective treatment, and empirical antitoxin administration can be initiated immediately upon suspicion of botulism. Early detection and timely specific treatment are critical for improving patient outcomes.

Using the research papers of Peking University Third Hospital recorded in SCIE since 2005 to 2014 as data basis, some bibliometric indexes were analyzed, including papers quality,cited times, impact factor, and funded papers.To reveal the current hospital research status and provide reference for policy drafting and subject development planning.In the past ten years, the quantity of paper increased significantly.However, highly impact papers published by Peking University Third Hospital were relatively rare, the cited times per paper in clinical medicine is lower than that of china mainland.It is necessary to improve the quality of research paper.

The literature retrieval course is the main form of current domestic medical infor-mation literacy education. But students have no interest in it, so it's difficult to realize the goal of in-formation literacy education. Information literacy education has the same ideas and goals with PBL in developing students' ability to ask questions, analyze and solve problems, as well as in improving students' autonomous learning and life-long learning ability. To study the model of medical information literacy education embedded in PBL from three stages that early course preparation, mid implementa-tion and later evaluation. The research is aimed at the improvement of students' information literacy and their lifelong study ability. It suggests that there are coordinated effects between PBL and informa-tion literacy.

The use of electronic resources and needs of novel services in readers of our library and their suggestions for library website construction were investigated with questionnaires and suggestions were put forward for improving and deepening the information service in hospital library.