Enzyme based immune balance is rather complicated subject that both biochemistry and immunology are involved in.It means that in human body,activity of enzymes and immune system network are interconnected and communicated together keeping a mobile balanced state.This state plays critically important role in maintaining normal physiological function of body.Once this balance is broken there must be something wrong with body.This article reviews functions of enzymes,regulation of immune sys-tem,as well as interaction between them.

Enzyme based immune balance is rather complicated subject that both biochemistry and immunology are involved in.It means that in human body,activity of enzymes and immune system network are interconnected and communicated together keeping a mobile balanced state.This state plays critically important role in maintaining normal physiological function of body.Once this balance is broken there must be something wrong with body.This article reviews functions of enzymes,regulation of immune sys-tem,as well as interaction between them.

Objective To investigate the clinical results of microsurgical free tissue transfers in pediatric reconstruction.Methods Between Janua~ 2004 and December 2010,twenty-seven free tissue transfers for reconstruction of various defects in 27 pediatric patients were performed.The average age at the time of reconstruction was 10.8 years(range:5-14 years).Fourteen patients were boys and 13 were girls.There were 5 tumor resection defects,sixteen posttraumatic defects and 6 burn contractures which consist of 19 fasciocutaneous flaps,six osteoseptocutaneous flaps and 2 muscle flaps.The mean operative time was 4 hours and 20 minutes.Results All flaps survived except 1 partial necrosis,with 96.3％ success rate.All patients were followed up 3 months to 4 years (mean,one and a half years).The appearance of the flaps was slightly overstaffed,but the color and texture were satisfactory.Conclusion Free tissue flap transfer is a safe,reliable,cost-and time-effective method for the reconstruction of various defects in children.