1.Gesture accuracy recognition based on grayscale image of surface electromyogram signal and multi-view convolutional neural network.
Qingzheng CHEN ; Qing TAO ; Xiaodong ZHANG ; Xuezheng HU ; Tianle ZHANG
Journal of Biomedical Engineering 2024;41(6):1153-1160
This study aims to address the limitations in gesture recognition caused by the susceptibility of temporal and frequency domain feature extraction from surface electromyography signals, as well as the low recognition rates of conventional classifiers. A novel gesture recognition approach was proposed, which transformed surface electromyography signals into grayscale images and employed convolutional neural networks as classifiers. The method began by segmenting the active portions of the surface electromyography signals using an energy threshold approach. Temporal voltage values were then processed through linear scaling and power transformations to generate grayscale images for convolutional neural network input. Subsequently, a multi-view convolutional neural network model was constructed, utilizing asymmetric convolutional kernels of sizes 1 × n and 3 × n within the same layer to enhance the representation capability of surface electromyography signals. Experimental results showed that the proposed method achieved recognition accuracies of 98.11% for 13 gestures and 98.75% for 12 multi-finger movements, significantly outperforming existing machine learning approaches. The proposed gesture recognition method, based on surface electromyography grayscale images and multi-view convolutional neural networks, demonstrates simplicity and efficiency, substantially improving recognition accuracy and exhibiting strong potential for practical applications.
Electromyography/methods*
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Neural Networks, Computer
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Humans
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Gestures
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Signal Processing, Computer-Assisted
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Machine Learning
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Pattern Recognition, Automated/methods*
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Algorithms
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Convolutional Neural Networks
2. Analysis of HA1 gene of influenza A H1N1 pdm09 virus from a clustered human cases
Pengfei YANG ; Qingli YAN ; Xuezheng MA ; Liping ZHANG ; Wei ZHEN ; Chuncheng LIU ; Yadong XING ; Haibo YAO ; Nanjiang HE ; Kongxin HU
Chinese Journal of Experimental and Clinical Virology 2017;31(1):42-46
Objective:
To understand the viral etiology of a clustered case of human infection outbreak in the middle school of Huai’an city.
Methods:
Nasopharyngeal swab samples from patients were collected and rapidly detected by Real-time RT-PCR and the target virus isolated in cells. Furthermore, HA1 segments of target virus were amplified by RT-PCR and sequenced. The genetic and phylogenetic analysis based on HA1 genes was computed.
Results:
Influenza A(H1N1)pdm09 viral nucleic acid in 11 nasopharyngeal swab samples from patients in the outbreak were positive. Compared to the vaccine strains A/California/07/2009, the Huai’an isolates, nucleotide identity was 97.7%-98.1%, and amino acid identity was 96.6%-97.4%. Phylogenetic analysis of HA1 segment sequences indicated that the Huai’an strains from the outbreak were related closely to the viruses isolated in the year of 2014. Sequence analysis indicated that the Huai’an isolates had no amino acid substitution in the receptor binding sites and glycosylation sites, while in the Ca1 of antigenic determinant of HA1 the Huai’an isolates had an amino acid substitution of S for T at 220.
Conclusions
The pathogen of the clustered case of human infection was Influenza A(H1N1)pdm09 virus. Though the Huai’an isolates had one animo acid substitution in the Ca1 of antigenic determinant, the antigenicity characteristic remained unchanged.
3.Comparison of efficacy and economic efficiency of neuroendoscope versus microscope for intracerebral hemorrhage
Xuezheng FAN ; Jinneng HUANG ; Shouhong ZHU ; Shuangui HU ; Boqiang WANG
The Journal of Practical Medicine 2016;32(18):3007-3010
Objective To investigate the differences of efficacy and economic efficiency between neuroendoscope and microscope for intracerebral hematomas cleaning operation. Methods From August 2014 to August 2015, clinical data of 68 cases with intracerebral hemorrhage were analyzed retrospectively. Hematoma evacuation was carried out by microscope in 37 cases (microscope group) received and 31 cases (endoscope group) underwent neuroendoscope. Following parameters were compared: the operation related index (hematoma clearance rate , intraoperative blood loss , the operation time , skin incision , bone window size ) , Glasgow Outcome Scale at 6 months after the operation, complications (intracranial infection, lung infections, gastrointestinal bleeding), medical economic parameters (the postoperative hospital stay, drug cost, cost other than drug, and total hospital cost). Results The hematoma clearance rate, Glasgow Outcome Scale at 6 months after the operation in the endoscope group were significantly better than those in the microscope group (P <0.05). The intraoperative blood loss, the operation time, skin incision, bone window size the postoperative hospital stay , drug costs , no drug costs , and total hospital cost in the neuroendoscope group were significantly lower than those in the microscope group (P < 0.01). The intracranial infection, lung infections in the neuroendoscope group were lower those in the microscope group (P < 0.05). There was no statistical difference in the incidence of gastrointestinal bleeding between the two groups (P > 0.05). The postoperative hospital stay, drug costs , no drug costs , and total hospital cost were significantly less in neuroendoscope group than that in microscope group (P< 0.01). Conclusion Neuroendoscopy has less trauma,there are some advantages of neuroendoscopy for intracerebral hematomas cleaning operation , such as minimal trauma , prominent effect , good prognosis and low cost. It should be widely applied in clinical practice.
4.Integrating immunomagnetic bead enrichment with immunochromatography for the detection of in-fluenza A virus
Xuemin WU ; Liping ZHANG ; Xuezheng MA ; Yong ZHAO ; Jimin GAO ; Kongxin HU
Chinese Journal of Microbiology and Immunology 2016;36(4):310-315
Objective To establish a novel method by integrating immunomagnetic bead enrich-ment with immunochromatography for the detection of influenza A virus. Methods The immunomagnetic beads were prepared by using EDC/NHS method and then coupled with monoclonal antibodies against influ-enza A virus. A direct immunomagnetic beads-based immunochromatography for the detection of influenza A virus was developed by using double-antibody sandwich method and immunochromatography, which was fur-ther combined with immunomagnetic separation to establish the novel integrated method of immunomagnectic bead enrichment and immunochromatography. Clinical throat swab samples collected from patients with influ-enza A virus infection and healthy subjects were analyzed by the novel method and the results were compared with those by using the conventional colloidal gold immunochromatography to evaluate the specificity, sensi-tivity and positive coincidence rate of this established method. Results The direct immunomagnetic beads-based immunochromatography and the colloidal gold immunochromatography showed no significant differences in specificity and sensitivity and could be used to identify influenza A virus-positive samples with cycle threshold ( Ct) values less than or equal to 22 obtained by real-time PCR assay. The integrated method could identify positive samples with Ct values less than or equal to 28, indicating that the novel method was more sensitive. Conclusion The novel method by integrating immunomagnetic bead enrichment with immunochroma-tography was successfully established and suitable for the rapid and on-site detection of influenza A virus.
5.Association of metabolic syndrome and chronic kidney diseases in Zhengzhou adults
Dan GAO ; Zhangsuo LIU ; Dongwei LIU ; Xiaozhou HU ; Pei WANG ; Xuezheng SHI
Chinese Journal of Endocrinology and Metabolism 2009;25(4):414-415
ortant risk factor for chronic kidney diseases.

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