Radiochemotherapy-induced oral mucositis (OM) is a common oral complication in patients with tumors following head and neck radiotherapy or chemotherapy. Erosion and ulcers are the main features of OM that seriously affect the quality of life of patients and even the progress of tumor treatment. To date, differences in clinical prevention and treatment plans for OM have been noted among doctors of various specialties, which has increased the uncertainty of treatment effects. On the basis of current research evidence, this expert consensus outlines risk factors, clinical manifestations, clinical grading, ancillary examinations, diagnostic basis, prevention and treatment strategies and efficacy indicators for OM. In addition to strategies such as basic oral care, anti-inflammatory and analgesic agents, anti-infective agents, pro-healing agents, and photobiotherapy recommended in previous guidelines, we also emphasize the role of traditional Chinese medicine in OM prevention and treatment. This expert consensus aims to provide references and guidance for dental physicians and oncologists in formulating strategies for OM prevention, diagnosis, and treatment, standardizing clinical practice, reducing OM occurrence, promoting healing, and improving the quality of life of patients.
Humans ; Chemoradiotherapy/adverse effects* ; Consensus ; Risk Factors ; Stomatitis/etiology*

The complexity of oral ulcerations poses considerable diagnostic and therapeutic challenges to oral specialists. The expert consensus was conducted to summarize the diagnostic work-up for difficult and complicated oral ulcers, based on factors such as detailed clinical medical history inquiry, histopathological examination, and ulceration-related systemic diseases screening. Not only it can provide a standardized procedure of oral ulceration, but also it can improve the diagnostic efficiency, in order to avoid misdiagnosis and missed diagnosis.
Consensus ; Humans ; Oral Ulcer/therapy*

Objective To explore the differences of curricula setting of medical students in China and the United States,and the enlightenment for medical education in China.Methods The curriculum of the 8-year students in Grade 2010 of Peking University was compared with the schedule of medical students in the same grade at the Pittsburgh University,specifically for the number of courses,the distribution of courses,the training of innovative abilities,and the doctor-patient communication courses.All the data were analyzed by SPSS 20.0,and t test and chi-square test were used for statistical analysis.Results The total number of courses in the two medical schools was similar.The number of study weeks per year for Peking University was (41.6 ± 8.7) weeks while that of Pittsburgh University was (39.6 ± 8.5)weeks,without statistically significant difference (t =1.414,P=0.200).Courses of both universities were distributed from comprehensive courses to medical courses and from basic courses to clinical courses,and the professional courses were similar.Innovative ability training and doctor-patient communication education were reflected in the curriculum of both universities,but the training courses of the University of Pittsburgh began earlier and the form was more flexible.Among them,there was a total of 47 learning hours of the doctor-patient communication lecture in Peking University while the number of Pittsburgh University was 140 learning hours,including lectures and communication with standard patients and real patients.The difference was statistically significant (~=67.45,P=0.000).Conclusion After more than 20 years of medical education reform,the curricula of medical students in China have basically reached the level of developed countries.Professional courses are similar to those of medical schools in developed countries.However,it is still necessary to strengthen the cultivation of innovative ability and medical humanities education.

Objective To study the effects of Chinese medicine compound on bone density, biomechanics, histomorphometry of weightlessness rats simulated by tail suspension. Methods Fifty Wistar rats were randomly divided into 5 groups with 10 rats each group:control group, model group, and low dose, medium dose and high dose Chinese medicine compound treated suspension group, the experiment period was 21 days. BMD of femur and lumbar vertebrae were detected by dual energy X-ray absorptiometry. The femoral biomechanics parameters and anti-compress ability of lumbar vertebrae were measured by three-point assay and compress test respectively. The quantitative structures of non- decalcified bone tissue sections were analyzed by histomorphometry. Result Compared with control group, BMD of femur and lumbar of model group decreased remarkably (P

0.05 ). However, benazepril+losartan group was better than benazepril group in improving heart composition and function (P