2- (2-thiophenyl) scopolamine glycolate is produced through an ester exchange reaction between scopine and methyl 2, 2-dithienylglycolate, and is used to synthesize tiotropium bromide. In this paper, the treatment process of 12 patients with acute 2- (2-thiophenyl) scopolamine glycolate poisoning was reviewed and their clinical data were analyzed. After a large amount of 2- (2-thiophenyl) scopolamine glycolate was absorbed through the respiratory tract, the poisoning patients presented with central nervous system injury as the main clinical manifestations, accompanied by symptoms such as blurred vision and irritability. After fluid replacement, ovulation induction and symptomatic supportive treatment, all patients improved and were discharged. The patients were followed up. After 6 months, only 3 patients had residual headache and dizziness. It is indicated that early intervention for acute 2- (2-thiophenyl) scopolamine glycolate poisoning has a good prognosis. Meanwhile, occupational protection should be strengthened to prevent the occurrence of poisoning.

2- (2-thiophenyl) scopolamine glycolate is produced through an ester exchange reaction between scopine and methyl 2, 2-dithienylglycolate, and is used to synthesize tiotropium bromide. In this paper, the treatment process of 12 patients with acute 2- (2-thiophenyl) scopolamine glycolate poisoning was reviewed and their clinical data were analyzed. After a large amount of 2- (2-thiophenyl) scopolamine glycolate was absorbed through the respiratory tract, the poisoning patients presented with central nervous system injury as the main clinical manifestations, accompanied by symptoms such as blurred vision and irritability. After fluid replacement, ovulation induction and symptomatic supportive treatment, all patients improved and were discharged. The patients were followed up. After 6 months, only 3 patients had residual headache and dizziness. It is indicated that early intervention for acute 2- (2-thiophenyl) scopolamine glycolate poisoning has a good prognosis. Meanwhile, occupational protection should be strengthened to prevent the occurrence of poisoning.

Objective:To explore the application effect of the tutorial system combined with one minute preceptor (OMP) in the standardized residency training of emergency medicine.Methods:A total of 48 residents who trained in the Department of Emergency, Zaozhuang Municipal Hospital Affiliated to Jining Medical College from January 2017 to December 2019 for ≥ 3 months were assigned randomly into control group ( n=24) and observation group ( n=24). The control group were given the traditional teaching mode only; while the observation group were given the tutorial system combined with OMP teaching mode, that was, a tutor was assigned to each training resident, and the teaching and training was carried out according to the teaching plan. After the rotation, the graduation examination was conducted, and the differences between the two groups were compared. SPSS 22.0 software was used for t test. Results:The clinical skills examination scores of the control and observation group were (47.50±3.91) points and (43.80±6.52) points respectively, with significant differences between the two groups ( t=2.42, P=0.020). The clinical operation technology examination scores of the control and observation group were (80.00±6.51) points and (75.10±6.19) points respectively, with significant differences between the two groups ( t=2.68, P=0.010). The clinical skills score and operation techniques score of the residents in the observation group were significantly better than those in the control group, and both were better than before training. Conclusion:The new training method of tutorial system combined with OMP can improve the clinical skills and operation techniques of the emergency residents significantly, which is worth being popularized and applied in clinical teaching.