Objective To explore the power output and blood compatibility of a novel electromagnetic pulsatile blood pump. Methods First, a theoretical model was established to analyze the driving force of the blood pump, and the experimental driving voltage satisfying the conditions was calculated based on this model. Then, the output flow rate, output pressure characteristics and hemolysis performance of the new blood pump in vitro were preliminarily analyzed by simulated circulation experiments. Results The experimental result showed that when the pump load was 73-5 mmHg (9-78 kPa, 1 mmHg=0-133 kPa), the driving voltage was 35 V and the pulsation frequency was 75 beats/min, the flow rate of the pump was 3-18 L/min, producing high, low and average pressure of 132, 66, 98 mmHg (17-56, 8-78, 13-03 kPa), and the normalized index of haematolysis (NIH) in vitro was (0-049 15+0-003 75) mg/dL. Conclusions The new pulsatile blood pump can satisfy the clinical requirements for perfusion of isolated organs and short-term assistance of cardiopulmonary bypass, which is of great significance to the development of cardiopulmonary bypass blood pump.