Objective:To investigate the current status of vision-related quality of life in elderly patients with dry eye disease and explore its influencing factors.Methods:A convenience sampling method was used to select elderly patients with dry eye disease who visited the ophthalmology outpatient department of the Affiliated Hospital of Jiangnan University from June to December 2023. Data were collected using a general information questionnaire, the 25-Item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25), the Brief Illness Perception Questionnaire (BIPQ), and the Social Support Rating Scale (SSRS). Multiple linear regression analysis was conducted to identify factors influencing vision-related quality of life.Results:A total of 410 questionnaires were distributed and 407 valid responses were received, with an effective response rate of 99.3%. The mean score of NEI-VFQ-25 among the 407 elderly patients with dry eye disease was (61.14±18.11). Multiple linear regression analysis showed that illness perception, social support, education level, age, gender, smoking, and previous health education experience were significant factors influencing vision-related quality of life in these patients ( P<0.05) . Conclusions:Vision-related quality of life in elderly patients with dry eye disease is at upper middle level. Illness perception, social support, education level, age, gender, smoking, and health education experience are primary influencing factors. Targeted interventions by healthcare providers are necessary to improve the vision-related quality of life in elderly patients with dry eye disease.

Objective:To investigate the current status of vision-related quality of life in elderly patients with dry eye disease and explore its influencing factors.Methods:A convenience sampling method was used to select elderly patients with dry eye disease who visited the ophthalmology outpatient department of the Affiliated Hospital of Jiangnan University from June to December 2023. Data were collected using a general information questionnaire, the 25-Item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25), the Brief Illness Perception Questionnaire (BIPQ), and the Social Support Rating Scale (SSRS). Multiple linear regression analysis was conducted to identify factors influencing vision-related quality of life.Results:A total of 410 questionnaires were distributed and 407 valid responses were received, with an effective response rate of 99.3%. The mean score of NEI-VFQ-25 among the 407 elderly patients with dry eye disease was (61.14±18.11). Multiple linear regression analysis showed that illness perception, social support, education level, age, gender, smoking, and previous health education experience were significant factors influencing vision-related quality of life in these patients ( P<0.05) . Conclusions:Vision-related quality of life in elderly patients with dry eye disease is at upper middle level. Illness perception, social support, education level, age, gender, smoking, and health education experience are primary influencing factors. Targeted interventions by healthcare providers are necessary to improve the vision-related quality of life in elderly patients with dry eye disease.

Objective To investigate the effect of acute high altitude exposure on lung functions and the relationship between lung functions and acute mountain sickness ( AMS) .Method We collected the lung function and Lewis Lake data of 73 subjects (aged 18 to 26,male) at 400 m above sea-leve and those at high altitude(exposure to 3900 m, 5 d).Results Compared with sea-level, lung functions decreased in forced vital capucity (FVC), maximum midexpiratory flow(MMF), V50, V25 while forced expiratory volume in 1 second(FEV1), peak expiratory flow(PEF), V75 did not change.FVC, FEV1, PEF, MMF were used to analyze the relationship between lung functions and AMS .There was no difference in lung functions between AMS group and NON AMS group at sea-level, but lung functions of AMS group were significantly lower than those of NON AMS group in FVC , MMF at high altitude .There was difference between AMS group and NON AMS group in the rate of change of FVC and MMF .Logistic regression analysis showed that the rate of change of FVC was an independent risk factor , while correlation analysis showed that the change of FVC and the change of oxygen saturation were relevant.Conclusion Lung functions showed restrictive decrease after acute high altitude exposure .Changes of lung func-tions will increase hypoxia and susceptiblity to AMS .