Objective To evaluate the reliability,validity and response of evaluation scale of kidney deficiency and blood stasis syndrome in Parkinson disease(PD).Methods A total of 225 patients with PD and 30 healthy people of the same age were evaluated with the PD kidney deficiency and blood stasis syndrome evaluation scale with 18 syndrome items constructed in the previous study.Exploratory factor analysis was used to evaluate the structural validity of the scale;Cronbach's α coefficient was used to evaluate the internal consistency reliability of the scale;correlation coefficient analysis was used to evaluate the retest reliability and content validity of the scale;t test was used to evaluate the response of the scale.Results The cumulative variance contribution rate of five common factors extracted by exploratory factor analysis was 61.162%,and the factor load coefficients of each item were greater than 0.450;the overall Cronbach's α value of the scale was 0.863;the total score of the scale and the correlation coefficient of the scores of each dimension were greater than 0.6(P<0.01);there were significant differences in the scores of each dimension item between PD patients before and after treatment and healthy peers(P<0.01).Conclusion Evaluation scale for PD kidney deficiency and blood stasis syndrome has good reliability,validity and response,which can be applied to the quantitative scoring of kidney deficiency and blood stasis syndrome of PD and the efficacy evaluation of TCM treatment for PD patients.

Objective To construct and validate a risk predictive model for fatigue in soldiers during long voyage based on sleep,mood and constitution.Methods One thousand soldiers during long voyage were selected as research objects by random cluster sampling.The fatigue scale-14(FS-14),Pittsburgh sleep quality index(PSQI),self-rating anxiety scale(SAS),self-rating depression scale(SDS),and TCM constitution scale were used to assess the occurrence of fatigue and its influence factors.Logistic stepwise regression analysis was used to screen variables,and the prediction nomogram model was constructed based on the risk factors of fatigue.The area under the receiver operator characteristic curve(AUC),calibration curve,Hosmer-Lemeshow test and decision curve were used for internal validation and predictive efficacy assessment.Results A total of 935 effective scales were collected,with an effective rate of 93.5%.Excluding 306 soldiers who were already fatigued before voyage,the fatigue incidence rate of 629 soldiers after 15 days and 30 days of voyage were 26.39%and 42.13%,respectively.The total score of FS-14 and the scores of physical fatigue and mental fatigue were significantly proportional to the voyage time(P<0.01).Eight variables including Qi-deficiency,Yang-deficiency,Yin-deficiency,Qi-stagnation,Special-constitution,anxiety,depression,and sleep disorder might be the independent risk factors for the occurrence of fatigue 30 days after voyage.A nomogram model was established according to the selected variables,and the AUC of the model was 0.828(95%CI:0.797-0.858).Calibration curve and Hosmer-Lemeshow test showed that the goodness of fit of the model was good(χ2=15.384,P=0.052).Decision curve showed that the model had a positive net benefit when the threshold probability was 10%-95%.Conclusion The predictive model for fatigue in soldiers during long voyage has good predictive accuracy and efficiency.It is an effective assessment tool for screening high-risk cases of fatigue and implementing preventive interventions in soldiers during long voyage.

Objective To evaluate the reliability,validity and response of evaluation scale of kidney deficiency and blood stasis syndrome in Parkinson disease(PD).Methods A total of 225 patients with PD and 30 healthy people of the same age were evaluated with the PD kidney deficiency and blood stasis syndrome evaluation scale with 18 syndrome items constructed in the previous study.Exploratory factor analysis was used to evaluate the structural validity of the scale;Cronbach's α coefficient was used to evaluate the internal consistency reliability of the scale;correlation coefficient analysis was used to evaluate the retest reliability and content validity of the scale;t test was used to evaluate the response of the scale.Results The cumulative variance contribution rate of five common factors extracted by exploratory factor analysis was 61.162%,and the factor load coefficients of each item were greater than 0.450;the overall Cronbach's α value of the scale was 0.863;the total score of the scale and the correlation coefficient of the scores of each dimension were greater than 0.6(P<0.01);there were significant differences in the scores of each dimension item between PD patients before and after treatment and healthy peers(P<0.01).Conclusion Evaluation scale for PD kidney deficiency and blood stasis syndrome has good reliability,validity and response,which can be applied to the quantitative scoring of kidney deficiency and blood stasis syndrome of PD and the efficacy evaluation of TCM treatment for PD patients.

Objective To investigate the distribution of Traditional Chinese Medicine(TCM)constitutions of offshore personnel of different categories and its correlation with health status.Methods The TCM constitution scale and sub-health measurement scale were used to assess TCM constitutions and health status of offshore personnel recuperating at Qingdao Special Service Sanatorium of Navy.And the results were statistically analyzed.Results There were 349(75.38%)persons with biased constitution among 463 interviewees.Damp-heat(20.83%),Yang deficiency(18.82%)and Yin deficiency(15.99%)were the common TCM constitutions.The TCM constitutions varied among different categories of offshore personnel.Yang deficiency and damp-heat were more common in surface warship crews and submarine crews.Aerial and land-based staffs were more prone to damp-heat and Yin deficiency.There were 293(63.28%)sub-healthy subjects among 463 interviewees,and 285(97.27%)of them had biased constitution.There was a significantly negative correlation between gentleness type and sub-health.Conclusion There is a relatively high proportion of offshore personnel with biased constitution and sub-health,and there is a significant correlation between biased constitution and sub-health.

Objective:To investigate the common diseases and the Constitution of Traditional Chinese Medicine of plateau-related soldiers, and explore the correlation between them.Methods:A total of 271 plateau-related soldiers in our sanatorium from January 1, 2020 to December 31, 2020 were selected as the subjects. All of them were assessed by the TCM constitution scale and the self-designed disease questionnaire and Sociodemographic information.Results:Eighty two percent of 271 plateau-related soldiers were regarded as paranoid constitution and 17.7% were gentleness type. There 73.1% of plateau-related soldiers had one or more diseases, and 90.9% of them were paranoid constitution. There were 47 cases of respiratory diseases, including 2 cases of gentleness type (4.3%) and 45 cases of paranoid constitution (95.7%); 53 cases of digestive system diseases, including 1 case of gentleness type (1.9%) and 52 cases of paranoid constitution (98.1%); 27 cases of skin diseases, including 1 case of gentleness type (3.7%) and 26 cases of paranoid constitution (96.3%); 148 cases of musculoskeletal diseases, including 15 cases of gentleness type (10.1%) and 133 cases of paranoid constitution (89.9%). The digestive system diseases with the highest proportion of paranoid constitution were selected for TCM Constitution correlation analysis, suggesting that there was a correlation between them( χ2=11.32, P<0.01). People including Qi deficiency and phlegm-dampness were more prone to digestive system diseases ( P<0.01). There was a significant negative correlation between gentleness type and digestive system diseases [ OR=0.17, 95% CI(0.040-0.726); P=0.017], as well as Qi deficiency [ OR=4.98, 95% CI(2.717-9.120)] and phlegm-dampness [ OR=12.00, 95% CI(5.269-27.332)]were risk factors for them ( P<0.01). Conclusions:The overall health level of plateau-related soldiers was not optimistic. The digestive system diseases of them were positively correlated with Qi deficiency and phlegm-dampness.

Objective:To investigate the effect of medicinal diet on lymphocyte proliferative activity in nuclear-related special service convalescents.Methods:A total of 324 nuclear-related special service convalescents admitted in our center were randomly divided into common diet group ( n=157)and medicated diet group ( n=167). The lymphocyte proliferation activity and the lymphocyte proliferation activity after oxidative damage by hydrogen peroxide in each group were measured on admission and discharge. Results:There was no significant difference between the lymphocyte proliferation activities of the two groups on admission ( P>0.05). On discharge, the lymphocyte proliferation activity of the nuclear-related special service convalescents in the medicated diet group increased significantly than that of the common diet group ( P<0.01). After oxidant application in vitro, the lymphocyte proliferation activity of the nuclear-related special service convalescents in the medicated diet group increased significantly than that of the common diet group on discharge ( P<0.05). Conclusion:The routine nutritional diet combined with medicated diet can improve the proliferation activity of lymphocyte in nuclear-related special service convalescents.

Objective:To investigate the effect of medicinal diet on lymphocyte proliferative activity in nuclear-related special service convalescents.Methods:A total of 324 nuclear-related special service convalescents admitted in our center were randomly divided into common diet group ( n=157)and medicated diet group ( n=167). The lymphocyte proliferation activity and the lymphocyte proliferation activity after oxidative damage by hydrogen peroxide in each group were measured on admission and discharge. Results:There was no significant difference between the lymphocyte proliferation activities of the two groups on admission ( P>0.05). On discharge, the lymphocyte proliferation activity of the nuclear-related special service convalescents in the medicated diet group increased significantly than that of the common diet group ( P<0.01). After oxidant application in vitro, the lymphocyte proliferation activity of the nuclear-related special service convalescents in the medicated diet group increased significantly than that of the common diet group on discharge ( P<0.05). Conclusion:The routine nutritional diet combined with medicated diet can improve the proliferation activity of lymphocyte in nuclear-related special service convalescents.