Objective:With the adjustment of epidemic prevention and control policies, the coronavirus disease infection has undergone incredible changes. The number of infected people has exploded in a geometric progression up to an astronomical number. In the face of a new round of stormy tests, it is not only necessary for the whole country to unite and help each other, unite as one, share weal and woe, and overcome the difficulties, but also for us to reflect on the current situation, problems and difficulties.

Earth is home not only to humans, but also to everything, including viruses. In the current globalization of coronavirus disease 2019 epidemic, the fluctuations of novel coronavirus makes epidemic prevention and control work normal, and the initiator of the accident, 2019 novel coronavirus, will coexist with human society for a long time. How we can coexist peacefully with them in this state is worth to thinking and studying.

The epidemic caused by COVID-19 has been highly concerned by the international community including World Health Organization (WHO). This is an ongoing battle for human life and health. We should always remember and learn lessons from the past, which could be promoted to all over the country, even the world. Many phenomena and problems in the work of epidemic prevention, control and treatment are worthy of our deep reflection. We should use scientific approach and dialectical materialism to make a practical and realistic summary. The purpose is to win the battle as soon as possible, and more importantly, to avoid repeating the same mistakes and prevent pestilence before it happens.

The epidemic caused by 2019 novel coronavirus has been highly concerned by the international community including World Health Organization (WHO). This is an endless battle against human life and health. Never forget the past, the teacher of the future. When you think hard, draw inferences from one instance. Many phenomena and problems in the work of epidemic prevention, control and treatment are worthy of our deep reflection. We should use scientific thinking and dialectical materialism to make a practical and realistic summary. The purpose is to win the battle as soon as possible, and more importantly, to avoid repeating the same mistakes and prevent trouble before it happens.

The transfer of critically ill patients is related to the treatment and prognosis of patients. It is not only the work of saving lives and injuries in the medical and health system, but also a measure of the ability and level of public health services in a region. "Non-emergency medical transshipment service" is a new form of business which is emerging at present. The phenomenon of "illegal ambulance" derived from it has attracted the attention of relevant government departments and has become the focus of media. The solution of this problem involves many aspects. The perspectives of defining the orientation of transfer work, constructing transfer service system, formulating transfer process norms and improving the quality of transfer efficiency are discussed in this paper, and it clearly puts forward that the development of "non-emergency medical transfer service" should adhere to the development path of marketization, diversification, standardization and specialization.

Objectives To study the clinical characteristics,diagnosis,treatment and prognosis of cancer metastases to the thyroid gland.Methods At Tianjin Medical University Cancer Hospital,from 1980 to 2016 30 patients were identified with a metastatic malignant tumor of the thyroid gland.Results Primary tumor sites were in the esophagus (26.7％),lung (16.7％),and kidney (13.3％).The median age at discovery of thyroid metastasis was 56 years old.The time lapse ranged from 0 to 108 months.There were 18 patients with metachronous metastasis with median survival of 36 months,12 patients were with synchronous metastasis,and the median survival was 8 months (P ＜ 0.01).20 patients were treated with thyroid surgery,and of which 15 patients were given post-op radiotherapy and chemotherapy.Patients who underwent thyroid resection had a median survival of 15 months,while that was 8 months in those without thyoid surgery (P ＜ 0.01).Conclusions Metastases to the thyroid gland is a rare clinical phenomenon,the prognosis of patients is mainly related to the biological behavior of primary tumors,but surgical resection and combined treatment can increase the survival rate.

Aviation medicine is being recognized as a rising star and an indispensable part of the "trinity"medical emergency network composed of land, water and air. The unparalleled mobility and traffic advantages of aircraft, especially rotorcraft (helicopter), are playing an increasingly important role in rescuing the dying and wounded, especially the critical patients, and thus derive a new medical operation mode. How to adapt to the development of the situation and the progress of the times, give full play to the advantages of aviation medical care? The key factors are improvement of the level of service efficiency, strength of learning, practice courage, innovation, and good at summing up to keep pace with the times.

Two strains of porcine reproductive and respiratory syndrome virus (PRRSV) were isolated in 2006 and 2016 and designated as FZ06A and FZ16A, respectively. Inoculation experiments showed that FZ06A caused 100% morbidity and 60% mortality, while FZ16A caused 100% morbidity without death. By using genomic sequence and phylogenetic analyses, close relationships between a Chinese highly pathogenic PRRSV strain and the FZ06A and FZ16A strains were observed. Based on the achieved results, multiple genomic variations in Nsp2, a unique N-glycosylation site (N³³→K³³), and a K151 amino acid (AA) substitution for virulence in the GP5 of FZ16A were detected; except the 30 AA deletion in the Nsp2-coding region. Inoculation experiments were conducted and weaker virulence of FZ16A than FZ06A was observed. Based on our results, a 30 AA deletion in the Nsp2-coding region is an unreliable genomic indicator of a high virulence PRRSV strain. The Nsp2 and GP5 differences, in addition to the virulence difference between these two highly pathogenic PRRSV strains, have the potential to be used to establish a basis for further study of PRRSV virulence determinants and to provide data useful in the development of vaccines against this economically devastating disease.
Asian Continental Ancestry Group ; China ; Genomics ; Humans ; Mortality ; Phylogeny ; Porcine Reproductive and Respiratory Syndrome ; Porcine respiratory and reproductive syndrome virus ; Vaccines ; Virulence

A discussion is made on the risk perception,lawful practice,team building, infrastructure,partnership,and operational mechanism of aviation medical rescue by hospitals,along with proposals for stakeholders and authorities for reference.