Objective:To investigate the occurrence and influencing factors of oral frailty among the elderly in China.Methods:General information questionnaire,Oral Frailty Scale,Sarcopenia Screening Questionnaire(SARC-F),Social Network Scale-6(LSNS-6)and Subjective Cognitive Decline Questionnaire(SCD-Q9)were used to conduct a survey in Anhui Province.A survey was conducted among 3 063 elderly people to analyze their current status and influencing factors related to oral frailty.Results:The incidence of oral frailty among the elderly in Anhui Province was 46.82％(1434/3063).Binary logistic regression analysis showed sarcopenia(OR=8.742,95％CI:7.156-10.679),social isolation(OR=1.601,95％CI:1.313-1.953),and subjective cogni-tive decline(OR=2.424,95％CI:1.905-3.085),90 years old and above(OR=2.261,95％CI:1.304-3.922)and having disability(OR=1.341,95％CI:1.040～1.729)are risk factors for oral frailty in the elderly in Anhui Province.Conclusion:The incidence of oral frailty is high among the elderly in Anhui Province.Risk factors for oral frailty include sarcopenia,social isolation,subjective cognitive decline,advanced age,and disability.

Objective:To systematically review the treatment and care experiences of elderly patients with comorbid chronic diseases, providing insights to meet patient healthcare needs and improve their treatment and care experiences.Methods:A computer-based search was conducted in the Cochrane Library, PubMed, Embase, Scopus, CINAHL, Medline, China National Knowledge Infrastructure, Wanfang Data, and VIP for qualitative studies on the treatment and care experiences of elderly patients with comorbid chronic diseases published from January 2019 to January 2024. The quality of the included studies was evaluated using the qualitative research quality assessment criteria developed by the Joanna Briggs Institute of Evidence-Based Health Care in Australia. A cumulative integration method was used to synthesize the results.Results:A total of 17 studies were included, extracting 42 results, which were categorized into 10 themes and integrated into four main findings: patients' varying levels of understanding about chronic comorbid conditions (some patients lack awareness of their current health condition, while others have a clear understanding of their disease status) ; treatment and care experiences across different comorbidity patterns (treatment and care experiences of cancer comorbidity patients, cardiovascular-metabolic comorbidity patients, respiratory system comorbidity patients, sensory-mental comorbidity patients, and visceral arthritis comorbidity patients) ; negative psychological emotions in patients with chronic comorbidity (special psychological experiences in cancer comorbid patients, emotional vulnerability in comorbid chronic disease patients leading to complex emotions) ; urgent needs of comorbid chronic disease patients (differing needs based on comorbidity patterns) .Conclusions:There are differences in the treatment and care experiences of elderly patients with chronic comorbidities, and they require multi-faceted support. Healthcare providers should offer personalized care to patients with different comorbid conditions to help them control their health conditions, optimize comorbidity management, and improve their quality of life.

Objective:To investigate the occurrence and influencing factors of oral frailty among the elderly in China.Methods:General information questionnaire,Oral Frailty Scale,Sarcopenia Screening Questionnaire(SARC-F),Social Network Scale-6(LSNS-6)and Subjective Cognitive Decline Questionnaire(SCD-Q9)were used to conduct a survey in Anhui Province.A survey was conducted among 3 063 elderly people to analyze their current status and influencing factors related to oral frailty.Results:The incidence of oral frailty among the elderly in Anhui Province was 46.82％(1434/3063).Binary logistic regression analysis showed sarcopenia(OR=8.742,95％CI:7.156-10.679),social isolation(OR=1.601,95％CI:1.313-1.953),and subjective cogni-tive decline(OR=2.424,95％CI:1.905-3.085),90 years old and above(OR=2.261,95％CI:1.304-3.922)and having disability(OR=1.341,95％CI:1.040～1.729)are risk factors for oral frailty in the elderly in Anhui Province.Conclusion:The incidence of oral frailty is high among the elderly in Anhui Province.Risk factors for oral frailty include sarcopenia,social isolation,subjective cognitive decline,advanced age,and disability.

Objective:To systematically review the treatment and care experiences of elderly patients with comorbid chronic diseases, providing insights to meet patient healthcare needs and improve their treatment and care experiences.Methods:A computer-based search was conducted in the Cochrane Library, PubMed, Embase, Scopus, CINAHL, Medline, China National Knowledge Infrastructure, Wanfang Data, and VIP for qualitative studies on the treatment and care experiences of elderly patients with comorbid chronic diseases published from January 2019 to January 2024. The quality of the included studies was evaluated using the qualitative research quality assessment criteria developed by the Joanna Briggs Institute of Evidence-Based Health Care in Australia. A cumulative integration method was used to synthesize the results.Results:A total of 17 studies were included, extracting 42 results, which were categorized into 10 themes and integrated into four main findings: patients' varying levels of understanding about chronic comorbid conditions (some patients lack awareness of their current health condition, while others have a clear understanding of their disease status) ; treatment and care experiences across different comorbidity patterns (treatment and care experiences of cancer comorbidity patients, cardiovascular-metabolic comorbidity patients, respiratory system comorbidity patients, sensory-mental comorbidity patients, and visceral arthritis comorbidity patients) ; negative psychological emotions in patients with chronic comorbidity (special psychological experiences in cancer comorbid patients, emotional vulnerability in comorbid chronic disease patients leading to complex emotions) ; urgent needs of comorbid chronic disease patients (differing needs based on comorbidity patterns) .Conclusions:There are differences in the treatment and care experiences of elderly patients with chronic comorbidities, and they require multi-faceted support. Healthcare providers should offer personalized care to patients with different comorbid conditions to help them control their health conditions, optimize comorbidity management, and improve their quality of life.

The development of longitudinal cohorts has made the identification and surveillance of multiple biological markers and behavioral factors which influence disease course or health status become possible. However, traditional statistical methods typically use univariate longitudinal data for research, failing to fully exploit the information from multivariate longitudinal data. The group-based multi-trajectory model (GBMTM) emerged as a method to study the developmental trajectory of multivariate data in recent years. GBMTM has distinct advantages in analyzing multivariate longitudinal data by identifying potential subgroups of populations following similar trajectories by multiple indicators that influence the outcome of interest. In this study, we introduced the application of GBMTM by explaining the fundamental principles and using the data from a health management study in the elderly by using smart wearing equipment to investigate the relationship between multiple life-related variables and hypertension to promote the wider use of GBMTM in longitudinal cohort studies.

Objective:To analyze the correlation between frailty and health literacy in elderly patients with chronic cardiac insufficiency.Methods:The convenience sampling method was used to select 290 elderly patients with chronic cardiac insufficiency who were hospitalized in the Department of Geriatrics and Department of Cardiovascular Medicine of a tertiary first-class hospital in Wuhu City from Mar 2022 to Jun 2022.The patients were investigated with the general information questionnaire,FRAIL scale,Health Literacy Management Scale,etc.Spearman analysis was used to analyze the correlation between frailty and health literacy.Binary logistic regression were used to analyze the risk factors of frailty in elderly patients with chronic cardiac insufficiency.Results:The incidence of frailty in elderly patients with chronic cardiac insufficiency was 22.8% .Spearman analysis showed that the total score of health literacy was negatively correlated with frailty(r=-0.291,P= 0.000).Results of binary logistic regression analysis showed that health literacy score(OR=0.419,95% CI:0.266-0.908),long-term insomnia(OR=6.466,95% CI:2.099-19.914),nutritional risk(OR=11.202,95% CI:3.983-31.508),depression risk(OR=10.014,95% CI:1.963-51.075),chronic disease types≥5(OR=12.784,95% CI:3.811-42.878),exercise self-efficacy(OR=0.512,95% CI:0.304-0.956),and chronic disease information acquisition ability(OR=0.512,95% CI:0.304-0.956)were independent predictors of frailty in elderly patients with chronic cardiac insufficiency(P＜0.05).Conclusions:The incidence of frailty in elderly patients with chronic cardiac insufficiency is high,and clinical staff should pay more attention to the elderly with frailty,especially patients with long-term insomnia,risk of nutrition and depression,coexistence of chronic diseases,low level of health literacy and exercise self-efficacy.Targeted measures should be actively taken to improve the quality of life of patients and reduce the readmission rate.

Objective:To explore the correlation between post-traumatic stress disorder(PTSD),resilience and quality of life of front-line medical staff in public health emergencies.Methods:From Nov to Dec 2020,the medical staff of 4 COVID-19 designated hospitals in Wuhan were investigated with the general demographic questionnaire,10-item Connor-Davidson Resilience Scale,PTSD Checklist for DSM-5 and Simplify Qualify of Life Scale.Spearman correlation analysis and hierarchical regression analysis were used to investigate the correlation between PTSD,resilience and quality of life.Results:A total of 545 questionnaires were collected in this survey and the valid effective rate was 97.8% (533/545).The score of psychological resilience,PTSD and quality of life of medical staff were 26(20,30),17(8,25),and 20(18,23),respectively.And 13.1% (70/533)of medical staff had obvious PTSD symptoms.There were significant differences in the score of quality of life among medical staff with different genders,occupations and PTSD levels.Spearman correlation analysis results showed that the score of PTSD was negatively correlated with quality of life and psychological resilience(r=-0.488 and-0.464,P＜0.01).The score of psychological resilience was positively correlated with the score of quality of life(r =0.578,P＜0.01).Psychological resilience and PTSD were important predictors of quality of life,with an explanatory capacity of 37.0% .Conclusions:PTSD is a risk factor for quality of life,and psychological resilience is a protective factor for quality of life.In public health emergencies,improving psychological resilience,preventing and treating PTSD can improve the quality of life of medical staff.

Objective:To investigate the effects of different levels of ophthalmic surgical stimulation on blood glucose in patients with type 2 diabetes mellitus(T2DM).Methods:From Mar to Oct 2021,236 patients with T2DM who underwent ophthalmic surgery in our hospital were enrolled,including 71 cases of secondary surgery,89 cases of tertiary surgery,and 76 cases of quaternary surgery.According to the operation time,the 236 patients were divided into groups A(＜60 min),B(60-120 min)and C(＞120 min).The preoperative and postoperative blood glucose levels were compared in patients with different levels of surgery,and in groups A,B and C.Results:The postoperative blood glucose level was lower than that before surgery in secondary and tertiary surgery,and it was higher than that before surgery in quaternary surgery(P＜0.05).The fluctuation value of blood glucose in secondary and tertiary surgery was higher than that in quaternary surgery(P＜0.05).In groups A,B and C,the postoperative blood glucose level was lower than that before surgery in secondary and tertiary surgery(P＜0.05).In group A,there was no significant difference in the blood glucose before and after surgery in quaternary surgery(P＞0.05),and in groups B and C,the postoperative blood glucose was higher than that before surgery in quaternary surgery(P＜0.05).In group A,there was no difference in the fluctuation value of blood glucose at different levels of surgery(P＞0.05).In group B,the fluctuation value of blood glucose in patients with secondary and tertiary surgery was higher than that in quaternary surgery(P＜0.05).In group C,the fluctuation value of blood glucose in patients with tertiary and quaternary surgery was higher than that in patients with secondary surgery(P＜0.05).Conclusions:For ophthalmic surgery patients with T2DM,the postoperative blood glucose values of patients undergoing secondary and tertiary surgery generally show a downward trend,while the postoperative blood glucose value of patients undergoing quaternary surgery generally shows an upward trend.It is suggested that clinical workers should actively manage the perioperative blood glucose of patients with high-level surgery.

Objective:To explore the application effect of ICU nursing sub-specialty management model in the clinical treatment of ICU patients.Methods:Based on the actual needs of ICU patients,a precise and systematic management plan including organizational structure,workflow,linkage mechanism,quality control system,dynamic follow-up,and scientific research transformation was formulated,to construct a working model of multi-linkage,multi-direction supplement and coordinated development of two-way feedback mechanism in sub-specialty nursing.The control group was set before the implementation of ICU nursing sub-specialty management mode(Jan 1 to Dec 31,2021),and the intervention group was set after the implementation of ICU nursing sub-specialty management model(Jan 1 to Dec 31,2022).The core competence,specialty,sensitive indicators,satisfaction,and impact on patients were compared before and after implementation.Results:After the implementation of the ICU nursing sub-specialty management model,the core competence of nurses was improved,and the hospitalization time and mechanical ventilation time of patients were reduced,the incidence of re-entry ICU,acquired weakness,acquired dysphagia and incontinence dermatitis was decreased,the proportion of unplanned extubation was decreased,and the satisfaction of patients,nurses,doctors and students was improved(P＜0.05).Conclusion:The construction of ICU nursing sub-specialty management model can effectively promote the construction of ICU nursing sub-specialty,improve the core competence of nurses,reshape the connotation of nursing,improve the prognosis of patients,and ultimately promote the benign and sustainable development of hospital nursing.

Objective To design and produce a bleeding alert bandage and investigate its effectiveness in patients undergoing hemodialysis.Methods The bleeding alert bandage consists of elastic bandage,monitoring element and monitoring box.A convenience sampling method was used to select patients who received regular hemodialysis treatment in the blood purification center of a tertiary A comprehensive hospital in Anhui Province from January 2021 to June 2021.These patients were randomly assigned into an experimental group and a control group,with 40 cases in each group.Patients in the control group were inspected every 30 min by traditional method.Patients in the experimental group were monitored in real-time with a bleeding alert bandage in addition to the 30 min rounds.The detection rate,incidence,and volume of bleeding at the puncture site were compared in 2 groups of patients.Results The incidence of bleeding from the puncture sites was 17.00％in the experimental group and 25.25％in the control group,with statistical significance(x2=8.170,P=0.004).The incidence of bleeding for severe bleeding from puncture sites was 1.50％in the experimental group and 11.50％in the control group,with statistical significance(x2=32.910,P＜0.001).The bleeding detection rate from puncture sites was 94.12％in the experimental group and 89.11％in the control group,with no statistical difference(x2=1.261,P=0.262).The detection rate for moderate bleeding from puncture sites was 100％in the experimental group and 85.37％in the control group,with statistical significance(x2=6.170,P=0.013).Additionally,the bleeding volume from the puncture site was 1.29(0.88,1.74)g in the experimental group and 2.77(1.60,4.77)g in the control group,with statistical significance(Z=-5.825,P＜0.001).The moderate bleeding volume from the puncture site was 1.49(1.27,1.81)g in the experimental group and 1.92(1.52,2.44)g in the control group,with statistical significance(Z=-2.835,P=0.005).Conclusion The bleeding alert bandage is effective in real-time monitoring and alerting of bleeding at the puncture sites during hemodialysis,which can help reduce the incidence of blood seepage,improve the detection rate of blood seepage,reduce the amount of bleeding and improve the safety of dialysis treatment.