In the context of an aging population, diabetes has emerged as a significant public health challenge.However, compared to the extensive research on target organs such as the cardiovascular, nervous, and renal systems, the impact of diabetes on the skeletal system has been underestimated.The pathological microenvironment of diabetes and systemic internal environment disorders harm bones by affecting bone density, disrupting bone microstructure, interfering with the bone mineralization process, and reducing the quality of bone collagen, which leads to the development of osteoporosis.Therefore, maintaining bone health should be an important component of comprehensive diabetes management.This review aims to provide an overview of the pathological characteristics, mechanisms, and treatment strategies for osteoporosis in both type 1 and type 2 diabetes, serving as a reference for bone health management in diabetic patients.

In the context of an aging population, diabetes has emerged as a significant public health challenge.However, compared to the extensive research on target organs such as the cardiovascular, nervous, and renal systems, the impact of diabetes on the skeletal system has been underestimated.The pathological microenvironment of diabetes and systemic internal environment disorders harm bones by affecting bone density, disrupting bone microstructure, interfering with the bone mineralization process, and reducing the quality of bone collagen, which leads to the development of osteoporosis.Therefore, maintaining bone health should be an important component of comprehensive diabetes management.This review aims to provide an overview of the pathological characteristics, mechanisms, and treatment strategies for osteoporosis in both type 1 and type 2 diabetes, serving as a reference for bone health management in diabetic patients.