Objective To integrate and optimize the hospital adverse event reporting system,and to enhance the repor-ting rate of medical safety adverse events by using PDCA cycle management method.Achieve closed-loop management of adverse events,improve the efficiency of adverse event management in the hospital,assist in hospital grading review and-quality develop-ment,and reduce the mortality rate of low-risk groups in the hospital.Methods Based on the SPO theory,the quality control circle,PDCA management,flow chart and description method were used,and combined with the previous adverse event manage-ment experience,the adverse event reporting and tracking process was simplified,and adverse event management information platform was optimized and restructured.The period from January to December 2023(control group)and the period from January to 2024(observation group)were compared and analyzed for the number of adverse event reports per 100 discharges and the mor-tality rate of the low-risk group before and after the implementation of PDCA cycle management.Results The application of PDCA cycle management effectively improved the reporting rate of medical safety adverse events and reduced the mortality rate of the hospital's low-risk group.Conclusion The integrated and designed adverse event management system has good applicability and can be promoted for use in hospital management.

Objective:To investigate the prevalence and influencing factors of depression,anxiety and comorbid depression-anxiety symptoms among college freshmen,providing a theoretical basis for promoting their mental health.Methods:From Jan to Feb 2022,an online questionnaire survey was conducted,involving 483 online questionnaires from college freshmen(184 males,299 females).The depression-anxiety-stress self-rating scale,smartphone dependence self-rating scale for adolescents,and Pittsburgh sleep quality index(PSQI)were used for online surveys.The influencing factors of depression,anxiety,and their comorbidity among college freshmen were analyzed by multivariable logistic regression analysis.Results:The detection rates of smartphone dependence,sleep disorders,depression,anxiety and comorbid depression-anxiety symptoms among college freshmen were 26.1%,12.8%,26.3%,32.1%,and 23.6%,respectively.The detection rates of depression,anxiety and comorbid depression-anxiety symptoms in male students were significantly higher than those in female students(P＜0.05).Multivariable logistic regression analysis showed that self-perceived poor mental health,smartphone dependence and sleep disorders were risk factors for depression,anxiety and comorbid depression-anxiety symptoms.Low satisfaction with college life was a risk factor for depression.Medical specialty was a risk factor for anxiety and comorbid depression-anxiety symptoms(P＜0.05).Conclusions:Male college freshmen show higher rates of depression,anxiety,and their comorbidity.Low satisfaction with college life,self-perceived poor mental health,high academic pressure,smartphone dependence,medical specialty,and sleep disorders may be risk factors for depression,anxiety and comorbid depression-anxiety symptoms among college freshmen.

Liquid chip technology is based on liquid carrier. Comparing to the traditional detection methods, it has unique characteristics such as multiple detection ability, high throughput, high sensitivity, good repeatability, less sample and fast analysis. It can analyse proteins, nucleic acids and other biological molecules in liquid. At present, it has been widely used in the laboratory diagnosis of tumors, autoimmune diseases, allergic diseases, cytokines related diseases, as well as infectious diseases. This article discussed the principles, detection performances, clinical applications and future prospects of liquid chip technology.

Teaching evaluation for university faculty is a cornerstone of achieving high-quality development of higher education. In Chinese medical universities, however, teacher evaluations predominantly rely on summative assessments, with insufficient emphasis on self-evaluation and peer review. This approach often leads to low evaluation effectiveness and minimal engagement of faculty development and training centers. By contrast, British universities have long-established and rapidly developed teacher evaluation systems that prioritize the developmental aspect of evaluation. These systems integrate multi-dimensional approaches, such as self-evaluation and peer review, significantly enhancing the quality of higher medical education through teacher evaluation. Drawing on the British teacher evaluation framework and adapting it to the specific context of Chinese medical universities, it is imperative to establish a diversified teacher evaluation mechanism. This mechanism should adopt self-evaluation, peer review, and scientific faculty development and training to motivate and cultivate teachers and thus improve teaching quality.

Objective To evaluate the efficacy rebound of congenital auricle deformation after noninvasive cor-rection of EarWell and study the environmental factors that may affect the occurrence of the disease.Methods ① A total of 86 children diagnosed with congenital auricle deformation in the First Hospital of Jilin University were se-lected as the treatment group(treated with EarWell),and the rebound after treatment was compared among differ-ent age groups(group A:3-7 days,31 ears,group B:8-42 days,59 ears,group C:＞42 days,33ears).② 77 chil-dren with normal auricle with similar age were selected as the control group,and the relevant information of the two groups of children was collected by questionnaire survey to analyze the risk factors that may affect the occurrence of the disease.Results ① A total of 13.0％of deformed ears developed rebound,with about 81.3％occurring within three months after the end of treatment.The rebound rate of group C was higher than those of groups A and B(P＜0.001),and there was no significant difference between groups A and B(P＞0.05).② Compared with the con-trol group,the parents in the treatment group were older at birth,the incidence of smoking of the father,abortion of the mother,hypertension and anemia of pregnancy was higher,and the incidence of folic acid supplementation and cesarean section of the mother was lower(P＜0.05).Multivariate logistic regression model analysis showed that paternal age(OR=1.58,P=0.003),hypertension during pregnancy(OR=4.39,P=0.004),and anemia during pregnancy(OR=3.72,P=0.005)were independent risk factors for congenital auricle deformation.Folic acid sup-plementation for mothers(OR=0.44,P=0.049)and cesarean section(OR=0.35,P=0.008)were the protective factors.Conclusion The rebound of congenital auricular deformation after non-invasive correction mostly occurred within three months after treatment,and the rebound rate of deformed ear with children of age greater than 42 days was higher.Moreover,its occurrence may be related to the age of the father,whether the mother regularly supple-ments folic acid,the mode of production,whether have hypertension or anemia during pregnancy.

Objective To evaluate the efficacy rebound of congenital auricle deformation after noninvasive cor-rection of EarWell and study the environmental factors that may affect the occurrence of the disease.Methods ① A total of 86 children diagnosed with congenital auricle deformation in the First Hospital of Jilin University were se-lected as the treatment group(treated with EarWell),and the rebound after treatment was compared among differ-ent age groups(group A:3-7 days,31 ears,group B:8-42 days,59 ears,group C:＞42 days,33ears).② 77 chil-dren with normal auricle with similar age were selected as the control group,and the relevant information of the two groups of children was collected by questionnaire survey to analyze the risk factors that may affect the occurrence of the disease.Results ① A total of 13.0％of deformed ears developed rebound,with about 81.3％occurring within three months after the end of treatment.The rebound rate of group C was higher than those of groups A and B(P＜0.001),and there was no significant difference between groups A and B(P＞0.05).② Compared with the con-trol group,the parents in the treatment group were older at birth,the incidence of smoking of the father,abortion of the mother,hypertension and anemia of pregnancy was higher,and the incidence of folic acid supplementation and cesarean section of the mother was lower(P＜0.05).Multivariate logistic regression model analysis showed that paternal age(OR=1.58,P=0.003),hypertension during pregnancy(OR=4.39,P=0.004),and anemia during pregnancy(OR=3.72,P=0.005)were independent risk factors for congenital auricle deformation.Folic acid sup-plementation for mothers(OR=0.44,P=0.049)and cesarean section(OR=0.35,P=0.008)were the protective factors.Conclusion The rebound of congenital auricular deformation after non-invasive correction mostly occurred within three months after treatment,and the rebound rate of deformed ear with children of age greater than 42 days was higher.Moreover,its occurrence may be related to the age of the father,whether the mother regularly supple-ments folic acid,the mode of production,whether have hypertension or anemia during pregnancy.

Objective To integrate and optimize the hospital adverse event reporting system,and to enhance the repor-ting rate of medical safety adverse events by using PDCA cycle management method.Achieve closed-loop management of adverse events,improve the efficiency of adverse event management in the hospital,assist in hospital grading review and-quality develop-ment,and reduce the mortality rate of low-risk groups in the hospital.Methods Based on the SPO theory,the quality control circle,PDCA management,flow chart and description method were used,and combined with the previous adverse event manage-ment experience,the adverse event reporting and tracking process was simplified,and adverse event management information platform was optimized and restructured.The period from January to December 2023(control group)and the period from January to 2024(observation group)were compared and analyzed for the number of adverse event reports per 100 discharges and the mor-tality rate of the low-risk group before and after the implementation of PDCA cycle management.Results The application of PDCA cycle management effectively improved the reporting rate of medical safety adverse events and reduced the mortality rate of the hospital's low-risk group.Conclusion The integrated and designed adverse event management system has good applicability and can be promoted for use in hospital management.

Objective To investigate the levels of serum adrenomedullin precursor(pro-ADM),soluble leukocyte differentiation antigen 14 subtype(presepsin),and eosinophil chemotactic factor-1(Eotaxin-1)in patients with acute stroke(AS)complicated with pulmonary infection and their relationship with prognosis.Methods A total of 146 patients with AS admitted to the hospital from January 2022 to January 2024 were selected as the research subjects.According to whether the research subjects were complicated with pulmonary infection,they were divided into the infection group with 54 cases and the non-infection group with 92 cases.In addition,100 healthy individuals who underwent physical examinations in the hospital during the same period were selected as the control group.The prognosis of patients was evaluated using the modified Rankin scale score,which was divided into good prognosis and poor prognosis.The levels of serum pro-ADM,presepsin,Eotaxin-1 and C-reactive protein(CRP)were detected by enzyme-linked immunosorbent assay.Multivariate Logistic regression was used to analyze the influencing factors of AS complicated with pulmonary infection,and the receiver operating characteristic(ROC)curve was plotted to analyze the diagnostic value of serum CRP,pro-ADM,presepsin,and Eotaxin-1 levels for patients with AS complicated with pulmonary infection.Compare the levels of serum pro-ADM,presepsin and Eotaxin-1 in patients with different prognoses.The rela-tionship between the levels of serum pro-ADM,presepsin and Eotaxin-1 and the prognosis of patients was ana-lyzed by the Kaplan-Meier method.Results The levels of smoking history and serum CRP,pro-ADM,presep-sin,and Eotaxin-1 in the infection group were higher than those in the non-infection group and the control group,and the difference was statistically significant(P<0.05).The results of multivariate Logistic regres-sion analysis showed that the levels of serum CRP,pro-ADM,presepsin and Eotaxin-1 were the influencing factors of AS complicated with pulmonary infection(P<0.05).The results of the ROC curve analysis show that the area under the curve(AUC)of the combined diagnosis of AS complicated with pulmonary infection by serum pro-ADM,presepsin and Eotaxin-1 levels was higher than AUC of the individual diagnosis of CRP,pro-ADM,presepsin and Eotaxin-1(Z=3.921,2.445,2.825,3.076,P<0.05).The levels of serum pro-ADM,presepsin and Eotaxin-1 in patients with poor prognosis were higher than those in patients with good progno-sis,and the difference was statistically significant(P<0.05).The results of survival analysis by the Kaplan-Meier method showed that the survival rate of patients with high expression of serum pro-ADM,presepsin,and Eotaxin-1 was lower than that of patients with low expression(P<0.05).Conclusion The levels of ser-um pro-ADM,presepsin and Eotaxin-1 in patients with AS complicated with pulmonary infection are related to their prognosis.

Objective To analyze the factors influencing the occupational health literacy (OHL) level among workers in key industries from the perspectives of both individual workers and enterprises. Methods A total of 32 336 front-line workers from 12 key industries in the secondary industry in Guangdong Province were selected as the research subjects by a stratified cluster random sampling method. Their OHL level was investigated using Occupational Health Literacy Questionnaire of National Key Populations, and the influencing factors were analyzed. Results The OHL level of the research subjects was 48.5%. The OHL level of the research subjects in four dimensions from high to low was basic knowledge of occupational health protection, occupational health practice and behavior, legal knowledge of occupational health, and basic skills of occupational health protection (80.7%, 61.2%, 48.3% and 29.5%, respectively). The multivariable logistic regression analysis showed that the OHL level of female workers was lower than that of males (P<0.05). Lower OHL was also associated with older age, lower education level, lower personal monthly income of workers (all P<0.01). The workers with length of service < 3 years and ≥ 20 years had lower OHL level than those with length of service 3-<10 years and 10-<20 years, respectively (all P<0.05). Workers in larger enterprises had higher OHL levels (all P<0.01). The OHL level of workers in the sixth category of industries with occupational injuries had higher occupational injury risks than those in the third and fourth categories (all P<0.05). The OHL levels of workers in state-owned enterprises, private enterprises, foreign-funded enterprises, and other enterprises were higher than that of workers in public institutions (all P<0.05). Conclusion The influencing factors of workers′ OHL in key industries of the secondary industry include individual factors (gender, age, education level, personal monthly income, length of service) and enterprise factors (enterprise size, enterprise nature and industry injury risk category). Female, older workers, those with lower education or income, and those with short length of service represent priority groups for OHL interventions, while small and micro enterprises are priority units for future workplace health promotion intervention.

Objective To analyze the current status and influencing factors of occupational health literacy (OHL) among noise-exposed workers in the automotive manufacturing industry. Methods A total of 1 188 front-line workers in noise-exposed positions in the automotive manufacturing industry were selected by judgment sampling method. The OHL status of the workers was investigated using the Occupational Health Literacy Questionnaire of National Key Population, and the influencing factors of OHL were analyzed. Results The overall OHL level was 30.13% (358/1 188). The result of binary logistic regression analysis showed that marital status, educational level, personal monthly income, household registration, enterprise scale and weekly working hours were influencing factors of OHL level (all P<0.05). Specifically, being married, having a high school education or higher, monthly personal income >5 000 yuan, being from a non-agricultural household, working in a medium-sized enterprise, and working more than >40-48 hours per week were protective factors for high OHL levels (all P<0.05). Conclusion There is considerable room for improvement in the OHL of noise-exposed workers in the automotive manufacturing industry. Focus should be placed on workers who are unmarried, widowed, or divorced, have educational levels below high school, earn less than 5 000 yuan per month, have agricultural household registrations, work in small or micro-sized enterprises, or work ≤40 hours per week, with targeted strategies to improve their overall OHL level.