Objective:To explore the impact of emotional intelligence on the moral sensitivity of nursing interns and the mediating effect of empathy, with the aim of providing a basis for nursing educators to conduct relevant training.Methods:From August 2023 to July 2024, 200 nursing interns from 4 third-level A-grade hospitals in Jilin Province were selected as study participants using a convenience sampling method. Surveys were conducted using a general information questionnaire, the Moral Sensitivity Scale for Nursing Students, the Chinese Version of the Emotional Intelligence Scale, and the Jefferson Empathy Scale.Results:A total of 200 questionnaires were distributed, with 185 valid responses. The total score of the Moral Sensitivity Scale for Nursing Students was (44.56±7.59), the total score of the Chinese Version of the Emotional Intelligence Scale was (65.15±14.67), and the total score of the Jefferson Empathy Scale was (91.30±18.82). Mediating effect analysis showed that emotional intelligence positively predicted moral sensitivity ( β=0.108, P<0.01), emotional intelligence positively predicted empathy ( β=0.548, P<0.01), and empathy positively predicted moral sensitivity ( β=0.193, P<0.01). The Bootstrap method was used to test the mediating effect of empathy, revealing that empathy partially mediated the relationship between emotional intelligence and moral sensitivity in nursing interns. The mediating effect value was 0.106, accounting for 49.53% (0.106/0.214) of the total effect. Conclusions:Emotional intelligence not only has a direct positive impact on the moral sensitivity of nursing interns but also indirectly affects moral sensitivity through the mediating effect of empathy. Nursing educators in medical schools should focus on cultivating both emotional intelligence and empathy in nursing students to enhance their moral sensitivity.

Aromatic traditional Chinese medicine(TCM) has played an important role against epidemics and viruses, and volatile components are the main components that exert the pharmacological effects of aromatic TCM. By screening the related monomer components in aromatic TCM against epidemic and viruses and analyzing and endowing TCM with medicinal properties based on its clinical application and pharmacological research according to the theoretical thinking of TCM, the key technical issues of compatibility of TCM monomer components were solved from a theoretical perspective, providing new ideas and methods for screening raw materials and formulas for the development of new TCM drugs. Based on the conditions of antiviral activity, clinical application foundation, definite therapeutic effect, and high safety, a gradient screening of aromatic TCM was carried out. Firstly, 30 aromatic TCM were screened from anti-epidemic literature and clinical trial formulas, and seven volatile monomers were further screened from them. Then, four monomer components with significant effects, namely patchouli alcohol, carvacrol, p-cymene, and eucalyptol were screened. By adopting the "four-step method for a systematic study of TCM properties", the four monomer components were endowed with medicinal properties, and compatibility and combination studies were conducted to explore the theoretical basis of monomer formulas and form monomer formulas guided by TCM theory. The screening results of volatile monomers in aromatic TCM against viral pneumonia included patchouli alcohol, carvacrol, p-cymene, and eucalyptol. The medicinal properties and compatibility theory of volatile monomer components in TCM were explored. Patchouli alcohol was the main herb, with a cool and pungent nature. It entered the lung meridian to dispel evil Qi and has the effects of aromatization, detoxification, and epidemic prevention. Carvacrol was a minister drug with a cool and pungent taste. It had the effects of aromatizing, moistening, and dissolving the exterior, as well as strengthening the spleen and stomach. p-Cymene was an adjunctive medicine with a mild and pungent nature. It entered the lungs and kidneys and had the effects of aromatic purification, cough relief, and asthma relief. Eucalyptol was also an adjunctive medicine with a pungent and warm taste. It had the functions of aromatic purification, cough relief, phlegm reduction, and pain relief. The combination of the four medicines had the effects of aromatizing, moistening, detoxifying, and epidemic prevention, as well as relieving cough and asthma and strengthening the spleen and stomach. They were used to treat viral pneumonia caused by upper respiratory tract viral infections, with symptoms such as chest tightness, cough, wheezing, fatigue, nasal congestion, runny nose, nausea, and vomiting. This study has laid a literature and theoretical foundation for further drug efficacy verification experiments, compatibility efficacy experiments, and subsequent product development and clinical applications, and it serves as an innovative practice that combines literature research, theoretical research, experimental research, and clinical practice to develop new products.
Drugs, Chinese Herbal/therapeutic use* ; Antiviral Agents/pharmacology* ; Humans ; Pneumonia, Viral/virology* ; Medicine, Chinese Traditional ; Volatile Organic Compounds/pharmacology* ; Animals

Objective:To explore the impact of emotional intelligence on the moral sensitivity of nursing interns and the mediating effect of empathy, with the aim of providing a basis for nursing educators to conduct relevant training.Methods:From August 2023 to July 2024, 200 nursing interns from 4 third-level A-grade hospitals in Jilin Province were selected as study participants using a convenience sampling method. Surveys were conducted using a general information questionnaire, the Moral Sensitivity Scale for Nursing Students, the Chinese Version of the Emotional Intelligence Scale, and the Jefferson Empathy Scale.Results:A total of 200 questionnaires were distributed, with 185 valid responses. The total score of the Moral Sensitivity Scale for Nursing Students was (44.56±7.59), the total score of the Chinese Version of the Emotional Intelligence Scale was (65.15±14.67), and the total score of the Jefferson Empathy Scale was (91.30±18.82). Mediating effect analysis showed that emotional intelligence positively predicted moral sensitivity ( β=0.108, P<0.01), emotional intelligence positively predicted empathy ( β=0.548, P<0.01), and empathy positively predicted moral sensitivity ( β=0.193, P<0.01). The Bootstrap method was used to test the mediating effect of empathy, revealing that empathy partially mediated the relationship between emotional intelligence and moral sensitivity in nursing interns. The mediating effect value was 0.106, accounting for 49.53% (0.106/0.214) of the total effect. Conclusions:Emotional intelligence not only has a direct positive impact on the moral sensitivity of nursing interns but also indirectly affects moral sensitivity through the mediating effect of empathy. Nursing educators in medical schools should focus on cultivating both emotional intelligence and empathy in nursing students to enhance their moral sensitivity.

OBJECTIVE: To study the load capacity and slow releasing kinetics of chloramphenicol in poly(DMAM-co-AA) hydrogel based on N,N-dimethyl acrylamide (DMAM) and acrylic acid (AA). METHODS: The dry hydrogel was soaked in chloramphenicol solution, fully saturated and swelled. The load capacity of chloramphenicol in the swelled hydrogel was investigated. The dry gel loaded chloramphenicol was put into the different solution and constantly stirred. At the same time, the release rate of chloramphenicol was studied. RESULTS: When themole ratio of reaction monomers (DMAM/AA) and concentration of chloramphenicol solution were increased, the load capacityof chloramphenicol was increased. The release rate of chloramphenicol was increased with temperature rising. The release rate of chloramphenicolin acidic or alkaline medium was larger than that in neutral medium. CONCLUSION: The load capacity of chloramphenicol in poly(DMAM-co-AA) hydrogel is increased with the solution concentration of chloramphenicol increasing. The release of chloramphenicolin various hydrogels is completed in the range of 8 to 12 h, and the total release rate of chloramphenicol could reach about 90%.

Objective to investigate the correlation between glutathione S- transferase gene M1,t1 and P1(GStM1,GStt1 and GStP1)poly-morphism and sperm DNA fragmentation index(DFI)in male patients with idiopathic infertile. Methods the study included 246 male patients with idiopathic infertility. Polymerase chain reaction(PCR)and polymerase chain reaction restriction fragment length polymorphism(PCR-RFLP) were used to identify the genotype of GStM1,GStt1 and GStP1,respectively. Sperm DFI was analyzed by flow cytometry with acridine orange staining. Results the sperm DFI was significantly higher in GStt1 gene null type group than in GStt1 gene wild type group(P < 0.01);and there were no significant differences in GStM1 and GStP1 gene mutation type groups when comparing with the wild type group(P > 0.05). Conclusion GStt1 gene deletion was positive associated with the sperm DFI in male idiopathic infertile patients.