1.Action mechanisms of thymic stromal lymphopoietin in various skin diseases
Xinxing JIN ; Sizhe LI ; Yagang ZUO
Chinese Journal of Dermatology 2021;54(10):915-919
Thymic stromal lymphopoietin (TSLP) , a cytokine similar to interleukin-7 (IL-7) , can promote the differentiation and proliferation of a variety of cells, promote the secretion of Th2 cytokines by these cells, and plays an important role in the immune system. In recent years, abnormal expression of TSLP has been found in many skin diseases, and its level is also related to the severity of some skin diseases, suggesting that TSLP may be a potential target for the treatment of various skin diseases. This review summarizes recent research progress in the role of TSLP in the occurrence and development of various skin diseases, including inflammatory diseases, immune diseases, genetic diseases and tumors, and provides a basis and some ideas for the diagnosis and treatment of related diseases.
2.Diabetes-related hearing loss
Jin HAO ; Xinxing FU ; Lin HUA ; Yongxin LI
Chinese Journal of General Practitioners 2018;17(6):428-431
3.Study on rapid microwave-ashing pretreatment method for radioactivity monitoring in food
Yiyao CAO ; Shunfei YU ; Zhiqiang XUAN ; Xinxing LI ; Yaoxian ZHAO ; Jin LUO ; Yihua LI ; Xiaoming LOU
Chinese Journal of Radiological Medicine and Protection 2018;38(1):43-47
Objective To establish a rapid,high-efficiency and clean way to monitor and pretreat the radioactivity in foods.Methods Food samples,20 kg each of cabbage,crucian,shrimp,pork and 20 L of milk,were collected around Qinshan nuclear power plant,totaling 10 samples for each food.Each type of foods was arranged in two groups each with 10 samples.Samples were pretreated using traditional ashing method (TAM) and microwave ashing method (WAM) separately.HDEHP were used for 90Sr separation and measurement.Calculations were made for the time spent on food pretreatment.The ash-fresh ratio and the recovery rate of 90Sr by the two different method were calculated,with the quality of ash being evaluated.Results The mean time spent on pretreatment was cabbage 20 h,crucian 54 h,shrimp 46 h,pork 58 h and milk 74 h for TAM group,and cabbage 8.5 h,crucian 26 h,shrimp 23 h,pork 26 h and milk 30 h for WAM group,respectively.The time spent by WAM was half the time less than by TAM,especially for animal edible product.The ash-fresh ratios from WAM group were higher than from TAM group.The recovery rates of 90Sr from WAM group in the analytical process were all above 75%,higher than from TAM group.Ashes produced by WAM were hoary,uniform,carbon residue-free and fully ashed.Conclusions WAM pretreatment can pretreat food rapidly,efficiently,cleanly with less loss and better ashing effect.These can meet the requirement of rapid pretreatment of radioactivity in food.
4.Investigation of radiological protection status and radiation exposure level at interventional workplace in Zhejiang province
Sanhu ZHAO ; Shouming WU ; Yaoxian ZHAO ; Shunfei YU ; Jin LUO ; Yihua LI ; Xinxing LI ; Zhiqiang XUAN
Chinese Journal of Radiological Medicine and Protection 2017;37(8):605-608
Objective To explore the current status of radiation protection in interventional procedure and to analyze the existent problems.Methods Using the random sampling,70 interventional radiology workplaces were selected from Hangzhou,Ningbo,Wenzhou,Shaoxing and Jinhua.Information on personal radiation protective products and equipment was collected by filling out the form by hospital and the radiation dose was monitored at various body parts of the workers and at the outside of the operating room.Results All hospitals have been equipped with personal radiation protective products and equipment,22 of which were not with these products and equipment as required.Chest,abdomen and lower limb of interventional radiology workers are easy to receive higher radiation dose than in head (F =4.85,4.92,P < 0.05).The acceptance rates among different body parts of the workers were difference significantly (x2 =35.14,14.92,P < 0.05).Using protective curtain can reduce the radiation dose significantly (t =11.61-68.28,P < 0.05).Meanwhile,it also can improve the acceptance rates significantly (x2 =6.09-28.45,P < 0.05).Conclusions It is necessary to strengthen the use of radiation protection equipment among interventional radiology workers to reduce the levels of the individual doses to them.Hospitals must enhance the routine monitoring for improved radiaton protection.

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