1.Herbal Textual Research on Malvae Semen in Famous Classical Formulas
Dongxue CHEN ; Yibo LIU ; Yangyang YU ; Guoshuai LYU ; Huili WU ; Xinle HAN ; Yue TAN ; Minhui LI ; Zhilai ZHAN
Chinese Journal of Experimental Traditional Medical Formulae 2025;31(7):252-264
The medicinal use of Malvae Semen has a long history. In this paper, by consulting the ancient materia medica, prescription, agronomy, literature and other aspects of the classics, the name, origin, evolution of scientific name, quality, harvesting and processing, functions and indications and others of Malvae Semen were systematically sorted out and verified, so as to provide a basis for the development and utilization of famous classical formulas containing this herb. According to the textual research, Shennong Bencaojing began to use Dongkuizi as the correct name, which was used in the past dynasties, and there were also aliases such as Kuicaizi, Huacai, and Kuizi. Through the original research, it can be seen that Kuicai is the mainstream original plant of Malvae Semen, that is, Malva verticillata var. crispa, the Alcea rosea and M. cathayensis are also used. In modern times, the seeds of Abutilon theophrasti have been passed off as Malvae Semen, while the seeds of M. verticillata var. crispa have rarely been used in medicine. And Abutili Semen has been another medicinal material with different efficacy since the collection of Newly Revised Materia Medica in the Tang dynasty. Since the Ming and Qing dynasties, the cultivation of Kuicai has been decreasing, while A. theophrasti is more common and easy to obtain, and Abutili Semen and Malvae Semen are similar in morphology and confused, which should be corrected. In addition, Malvae Fructus is a Mongolian customary medicinal herb, which is different from the traditional use of seeds in traditional Chinese medicine. Kuicai, as an important vegetable in history, was widely cultivated and gradually shrunk after the Song dynasty, it is now mainly produced in southern provinces. The quality evaluation of Malvae Semen is better for those with dry bodies, full grain, grayish brown color, no mud, and no impurities. The harvesting is generally in the autumn and winter. After drying, it is seeded, sieved peel and impurities, mashed, or slightly stir-fried to yellow-white color with gentle fire. It is sweet, cold and slippery in nature and taste, with the main effects of laxation, diuresis, lactation and elimination of swelling. The efficacy of Abutili Semen is clearing heat and removing toxicity, promoting diuresis and removing nebula, the efficacy is quite different from that of Malvae Semen. Based on the results of textual research, it is suggested that M. verticillata var. crispa should be used as the medicinal source of Malvae Semen in the development of famous classical formulas, the corresponding processing methods should be selected according to the requirements of drug processing in the formulas, while the raw products are recommended to be used if the processing is not specified.
2.Herbal Textual Research on Malvae Semen in Famous Classical Formulas
Dongxue CHEN ; Yibo LIU ; Yangyang YU ; Guoshuai LYU ; Huili WU ; Xinle HAN ; Yue TAN ; Minhui LI ; Zhilai ZHAN
Chinese Journal of Experimental Traditional Medical Formulae 2025;31(7):252-264
The medicinal use of Malvae Semen has a long history. In this paper, by consulting the ancient materia medica, prescription, agronomy, literature and other aspects of the classics, the name, origin, evolution of scientific name, quality, harvesting and processing, functions and indications and others of Malvae Semen were systematically sorted out and verified, so as to provide a basis for the development and utilization of famous classical formulas containing this herb. According to the textual research, Shennong Bencaojing began to use Dongkuizi as the correct name, which was used in the past dynasties, and there were also aliases such as Kuicaizi, Huacai, and Kuizi. Through the original research, it can be seen that Kuicai is the mainstream original plant of Malvae Semen, that is, Malva verticillata var. crispa, the Alcea rosea and M. cathayensis are also used. In modern times, the seeds of Abutilon theophrasti have been passed off as Malvae Semen, while the seeds of M. verticillata var. crispa have rarely been used in medicine. And Abutili Semen has been another medicinal material with different efficacy since the collection of Newly Revised Materia Medica in the Tang dynasty. Since the Ming and Qing dynasties, the cultivation of Kuicai has been decreasing, while A. theophrasti is more common and easy to obtain, and Abutili Semen and Malvae Semen are similar in morphology and confused, which should be corrected. In addition, Malvae Fructus is a Mongolian customary medicinal herb, which is different from the traditional use of seeds in traditional Chinese medicine. Kuicai, as an important vegetable in history, was widely cultivated and gradually shrunk after the Song dynasty, it is now mainly produced in southern provinces. The quality evaluation of Malvae Semen is better for those with dry bodies, full grain, grayish brown color, no mud, and no impurities. The harvesting is generally in the autumn and winter. After drying, it is seeded, sieved peel and impurities, mashed, or slightly stir-fried to yellow-white color with gentle fire. It is sweet, cold and slippery in nature and taste, with the main effects of laxation, diuresis, lactation and elimination of swelling. The efficacy of Abutili Semen is clearing heat and removing toxicity, promoting diuresis and removing nebula, the efficacy is quite different from that of Malvae Semen. Based on the results of textual research, it is suggested that M. verticillata var. crispa should be used as the medicinal source of Malvae Semen in the development of famous classical formulas, the corresponding processing methods should be selected according to the requirements of drug processing in the formulas, while the raw products are recommended to be used if the processing is not specified.
3.Research hotspot and trend of spino-pelvic sagittal balance:an analysis of 20 years of literature
Chinese Journal of Spine and Spinal Cord 2025;35(2):156-169
Objectives:To analyze the 100 most cited papers in the field of spino-pelvic sagittal balance since 2003,summarize and sort out the research hotspots and trends by using bibliometrics,in order to pro-vide references for related research and disease diagnosis and treatment in this field.Methods:The English literature in the field of spino-pelvic sagittal balance published from 2003 to 2023 was searched in the Web of Science Core Collection(WoSCC)database.According to the inclusion and exclusion criteria,the keywords,publication year,first author,publishing institution,country,publication journal,and total number of citations of the included literature were extracted for summary and visual analysis.VOSviewer,CiteSpace,RStudio and other bibliometric analysis tools were used to reveal the global trends and research hotspots in this field.Results:A total of 6804 articles were retrieved according to the search criteria set in this study.Based on the title,abstract and full text of the articles,the top 100 most cited articles were finally obtained,including 86 original articles and 14 reviews.58 articles were published between the year 2003 and 2019,and cited 200 times or more.The most cited article was"The impact of positive sagittal balance in adult spinal defor-mity",with a total of 1179 citations.The country with the largest number of publications was the United States.The journal published the most articles was Spine.The most published institution was the University of Washington.The most prolific first author was Lafage V.Balance was the most frequent keyword.After reading the full text,the topics of the literature were summarized into seven aspects:radiological parameters,surgery,complications,classification system,general overview,compensation mechanism and others.Conclu-sions:Radiological parameters,surgery,and complications are still the focus of current research.Minimally invasive surgical techniques and individualized treatment are the future research and development trends.The number of articles published by Chinese scholars is increasing,while the number of citations is relatively small.
4.Research hotspot and trend of spino-pelvic sagittal balance:an analysis of 20 years of literature
Chinese Journal of Spine and Spinal Cord 2025;35(2):156-169
Objectives:To analyze the 100 most cited papers in the field of spino-pelvic sagittal balance since 2003,summarize and sort out the research hotspots and trends by using bibliometrics,in order to pro-vide references for related research and disease diagnosis and treatment in this field.Methods:The English literature in the field of spino-pelvic sagittal balance published from 2003 to 2023 was searched in the Web of Science Core Collection(WoSCC)database.According to the inclusion and exclusion criteria,the keywords,publication year,first author,publishing institution,country,publication journal,and total number of citations of the included literature were extracted for summary and visual analysis.VOSviewer,CiteSpace,RStudio and other bibliometric analysis tools were used to reveal the global trends and research hotspots in this field.Results:A total of 6804 articles were retrieved according to the search criteria set in this study.Based on the title,abstract and full text of the articles,the top 100 most cited articles were finally obtained,including 86 original articles and 14 reviews.58 articles were published between the year 2003 and 2019,and cited 200 times or more.The most cited article was"The impact of positive sagittal balance in adult spinal defor-mity",with a total of 1179 citations.The country with the largest number of publications was the United States.The journal published the most articles was Spine.The most published institution was the University of Washington.The most prolific first author was Lafage V.Balance was the most frequent keyword.After reading the full text,the topics of the literature were summarized into seven aspects:radiological parameters,surgery,complications,classification system,general overview,compensation mechanism and others.Conclu-sions:Radiological parameters,surgery,and complications are still the focus of current research.Minimally invasive surgical techniques and individualized treatment are the future research and development trends.The number of articles published by Chinese scholars is increasing,while the number of citations is relatively small.
5.Analysis of Influencing Factors and Mechanism Model of Defensive Medicine based on Grounded Theory
Xinle YIN ; Huanyu ZHANG ; Juan ZHAO ; Chen WANG ; Yajie FENG ; Xinru LIU ; Yue ZHOU ; Libo LIANG
Chinese Hospital Management 2024;44(7):6-10,15
Objective To clarify the influencing factors of defensive medicine and provide ideas for preventing and re-solving defensive medicine.Methods Literature related to defensive medicine was searched,personnel related to de-fensive medicine were interviewed,and literature and interview data were coded with the method of grounded theo-ry,and related concepts and categories were summarized.Results After three levels of coding,52 initial concepts,23 initial categories,7 sub-categories and 3 main categories were sorted out,and the correlation among influencing factors was analyzed to build a three-dimensional model of"doctor-patient relationship-institutional system-social environment"influencing factors and their mechanism of action.Conclusion The influencing factors of defensive medi-cine mainly include doctor-patient relationship,institutional system and social environment.The three factors have an impact on defensive medicine through different mechanisms of action,which provides qualitative evidence for comprehensive analysis of factors in related studies of defensive medicine.
6.Analysis of Influencing Factors and Mechanism Model of Defensive Medicine based on Grounded Theory
Xinle YIN ; Huanyu ZHANG ; Juan ZHAO ; Chen WANG ; Yajie FENG ; Xinru LIU ; Yue ZHOU ; Libo LIANG
Chinese Hospital Management 2024;44(7):6-10,15
Objective To clarify the influencing factors of defensive medicine and provide ideas for preventing and re-solving defensive medicine.Methods Literature related to defensive medicine was searched,personnel related to de-fensive medicine were interviewed,and literature and interview data were coded with the method of grounded theo-ry,and related concepts and categories were summarized.Results After three levels of coding,52 initial concepts,23 initial categories,7 sub-categories and 3 main categories were sorted out,and the correlation among influencing factors was analyzed to build a three-dimensional model of"doctor-patient relationship-institutional system-social environment"influencing factors and their mechanism of action.Conclusion The influencing factors of defensive medi-cine mainly include doctor-patient relationship,institutional system and social environment.The three factors have an impact on defensive medicine through different mechanisms of action,which provides qualitative evidence for comprehensive analysis of factors in related studies of defensive medicine.
7.Analysis of Influencing Factors and Mechanism Model of Defensive Medicine based on Grounded Theory
Xinle YIN ; Huanyu ZHANG ; Juan ZHAO ; Chen WANG ; Yajie FENG ; Xinru LIU ; Yue ZHOU ; Libo LIANG
Chinese Hospital Management 2024;44(7):6-10,15
Objective To clarify the influencing factors of defensive medicine and provide ideas for preventing and re-solving defensive medicine.Methods Literature related to defensive medicine was searched,personnel related to de-fensive medicine were interviewed,and literature and interview data were coded with the method of grounded theo-ry,and related concepts and categories were summarized.Results After three levels of coding,52 initial concepts,23 initial categories,7 sub-categories and 3 main categories were sorted out,and the correlation among influencing factors was analyzed to build a three-dimensional model of"doctor-patient relationship-institutional system-social environment"influencing factors and their mechanism of action.Conclusion The influencing factors of defensive medi-cine mainly include doctor-patient relationship,institutional system and social environment.The three factors have an impact on defensive medicine through different mechanisms of action,which provides qualitative evidence for comprehensive analysis of factors in related studies of defensive medicine.
8.Analysis of Influencing Factors and Mechanism Model of Defensive Medicine based on Grounded Theory
Xinle YIN ; Huanyu ZHANG ; Juan ZHAO ; Chen WANG ; Yajie FENG ; Xinru LIU ; Yue ZHOU ; Libo LIANG
Chinese Hospital Management 2024;44(7):6-10,15
Objective To clarify the influencing factors of defensive medicine and provide ideas for preventing and re-solving defensive medicine.Methods Literature related to defensive medicine was searched,personnel related to de-fensive medicine were interviewed,and literature and interview data were coded with the method of grounded theo-ry,and related concepts and categories were summarized.Results After three levels of coding,52 initial concepts,23 initial categories,7 sub-categories and 3 main categories were sorted out,and the correlation among influencing factors was analyzed to build a three-dimensional model of"doctor-patient relationship-institutional system-social environment"influencing factors and their mechanism of action.Conclusion The influencing factors of defensive medi-cine mainly include doctor-patient relationship,institutional system and social environment.The three factors have an impact on defensive medicine through different mechanisms of action,which provides qualitative evidence for comprehensive analysis of factors in related studies of defensive medicine.
9.Analysis of Influencing Factors and Mechanism Model of Defensive Medicine based on Grounded Theory
Xinle YIN ; Huanyu ZHANG ; Juan ZHAO ; Chen WANG ; Yajie FENG ; Xinru LIU ; Yue ZHOU ; Libo LIANG
Chinese Hospital Management 2024;44(7):6-10,15
Objective To clarify the influencing factors of defensive medicine and provide ideas for preventing and re-solving defensive medicine.Methods Literature related to defensive medicine was searched,personnel related to de-fensive medicine were interviewed,and literature and interview data were coded with the method of grounded theo-ry,and related concepts and categories were summarized.Results After three levels of coding,52 initial concepts,23 initial categories,7 sub-categories and 3 main categories were sorted out,and the correlation among influencing factors was analyzed to build a three-dimensional model of"doctor-patient relationship-institutional system-social environment"influencing factors and their mechanism of action.Conclusion The influencing factors of defensive medi-cine mainly include doctor-patient relationship,institutional system and social environment.The three factors have an impact on defensive medicine through different mechanisms of action,which provides qualitative evidence for comprehensive analysis of factors in related studies of defensive medicine.
10.Analysis of Influencing Factors and Mechanism Model of Defensive Medicine based on Grounded Theory
Xinle YIN ; Huanyu ZHANG ; Juan ZHAO ; Chen WANG ; Yajie FENG ; Xinru LIU ; Yue ZHOU ; Libo LIANG
Chinese Hospital Management 2024;44(7):6-10,15
Objective To clarify the influencing factors of defensive medicine and provide ideas for preventing and re-solving defensive medicine.Methods Literature related to defensive medicine was searched,personnel related to de-fensive medicine were interviewed,and literature and interview data were coded with the method of grounded theo-ry,and related concepts and categories were summarized.Results After three levels of coding,52 initial concepts,23 initial categories,7 sub-categories and 3 main categories were sorted out,and the correlation among influencing factors was analyzed to build a three-dimensional model of"doctor-patient relationship-institutional system-social environment"influencing factors and their mechanism of action.Conclusion The influencing factors of defensive medi-cine mainly include doctor-patient relationship,institutional system and social environment.The three factors have an impact on defensive medicine through different mechanisms of action,which provides qualitative evidence for comprehensive analysis of factors in related studies of defensive medicine.

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