Objective To compare the image quality of readout-segmented diffusion weighted imaging(RESOLVE-DWI)and integrated slice-by-slice shimming diffusion weighted imaging(iShim-DWI)in patients with nasopharyngeal carcinoma.Methods A retrospective study was conducted on 26 patients with nasopharyngeal carcinoma confirmed by pathology.The imaging data included RESOLVE-DWI and iShim-DWI.The signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)of the two sequences were compared by one deputy chief imaging technician.And two experienced radiologists used the 5-point scoring scheme to compare the lesion clarity,image artifacts,and antideformation ability of the two sequences,repectively.Results The SNR and CNR of the iShim-DWI sequence were significantly higher than those of RESOLVE-DWI sequence(P＜0.01).While the subjective scores of lesion clarity,image artifacts,and antideformation ability on RESOLVE-DWI were significantly better than those of iShim-DWI,and the differences were statistically significant(P＜0.01).Conclusion Both RESOLVE-DWI and iShim-DWI obtained good images.With sufficient SNR and CNR,RESOLVE-DWI has clearer lesions and surrounding structures,higher image resolution,fewer artifacts,and better antideformation ability,thus providing clinical advantages in evaluating patients with good physical tolerance.

Objective To compare the image quality of readout-segmented diffusion weighted imaging(RESOLVE-DWI)and integrated slice-by-slice shimming diffusion weighted imaging(iShim-DWI)in patients with nasopharyngeal carcinoma.Methods A retrospective study was conducted on 26 patients with nasopharyngeal carcinoma confirmed by pathology.The imaging data included RESOLVE-DWI and iShim-DWI.The signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)of the two sequences were compared by one deputy chief imaging technician.And two experienced radiologists used the 5-point scoring scheme to compare the lesion clarity,image artifacts,and antideformation ability of the two sequences,repectively.Results The SNR and CNR of the iShim-DWI sequence were significantly higher than those of RESOLVE-DWI sequence(P＜0.01).While the subjective scores of lesion clarity,image artifacts,and antideformation ability on RESOLVE-DWI were significantly better than those of iShim-DWI,and the differences were statistically significant(P＜0.01).Conclusion Both RESOLVE-DWI and iShim-DWI obtained good images.With sufficient SNR and CNR,RESOLVE-DWI has clearer lesions and surrounding structures,higher image resolution,fewer artifacts,and better antideformation ability,thus providing clinical advantages in evaluating patients with good physical tolerance.

Objective To investigate the influence of different contrast agent injection schemes on imaging quality in neck enhanced CT examination.Methods A total of 150 patients who underwent neck enhanced CT examination were selected and randomly divided into three groups:groups A,B,and C,with 50 cases in each group.Group A adopted individualized injection scheme,group B used three-phase dual-flow contrast agent injection scheme,and group C used measured constant-speed injection scheme,respectively.The objective and subjective evaluation methods were used to assess the image quality of cervical vessel and non-vessel structures.Results Among the three groups of contrast agent injection schemes,the CT values of group A and group B were higher than those of group C except for the aortic arch and submandibular gland in objective evaluation,and the contrast-to-noise ratio(CNR)of group A and group B except for the left common carotid artery and right common carotid artery bifurcation was higher than that of group C.In subjective evaluation,there was no statistically significant difference in image quality among the three groups(P＞0.05),and group B effectively reduced the impact of hardening artifacts.Conclusion The post-injection dual-flow contrast agent injection scheme can achieve the same enhancement effect as other injection schemes while ensuring image quality and reducing the amount of contrast agent used in the examination.

Objective To explore the factors influencing the image quality of thyroid CT and the application value of optimization schemes in reducing streak artifacts in thyroid CT examinations.Methods A retrospective review of the data of 141 patients who underwent thyroid enhanced CT examinations was conducted to analyze the factors affecting image quality.After determining the influencing factors,a self-controlled study was conducted on 48 patients who underwent thyroid CT examinations to analyze the feasibility of the optimization scheme.Results The patients'body mass index(BMI),neck circumference,pharynx-jaw angle,and pharynx-jaw angle-to-neck circumference ratio showed statistically significant differences in their impact on image quality(P<0.05).Compared to the conventional scheme,the optimization scheme showed significantly higher subjective and objective image evaluations.The optimization scheme also significantly improved the diagnostic performance of the images,with statistically significant differences(P<0.05).There was no statistically significant difference in radiation dose between the two positions(P>0.05).Conclusion The optimization scheme can effectively reduce streak artifacts in thyroid CT examinations.

Objective:To explore the protective effects of hematoma aspiration combined with hyperbaric oxygen（HBO）therapy on the brain tissue of rats after cerebral hemorrhage.Methods:A total of 40 rats were randomly divided into four groups：sham operation group，model group，operation group（hematoma aspiration），and combined treatment group（minimally invasive hematoma aspiration + HBO），with 10 rats in each group. The neurological deficits of rats in each group were scored by Longa scoring method. The water content of the brain tissue of rats in each group was detected by dry/wet weight measurement. The pathological changes in the hippocampus tissue of rats in each group were observed by H&E staining. The number of hippocampal neuronal apoptosis of rats in each group was detected by TUNEL assay. The expression levels of brain derived neurotrophic factor（BDNF）and Aquaporin-4（AQP4）in the hippocampus of rats in each group were detected by qRT-PCR and Western blotting. The protein expressions of Bax，Bcl-2，JAK2，p-JAK2，STAT3，and p-STAT3 in the brain tissue of rats in each group were detected by Western blotting.Results:Compared with the sham operation group，the model group had significantly higher nerve injury function scores and brain tissue water content，and showed brain tissue hemorrhage，cell pyknosis，enlarged intercellular space，increased glial cells，and decreased neurons；the apoptosis level of hippocampal neurons in the model group increased（ P<0.05）；the AQP4，p-JAK2，and p-STAT3 expressions in the model group increased，while the BDNF expression in the model group decreased（ P<0.05）. Compared with the model group，the operation group and the combined treatment group had lower nerve injury function scores and less brain tissue water content，and the brain tissue injury in the two groups was reduced. In both groups，the apoptosis level of hippocampal neurons decreased（ P<0.05）；the AQP4，p-JAK2，and p-STAT3 expressions decreased，while the BDNF expression increased（ P<0.05）. Compared with the operation group，the combined treatment group had significantly lower nerve injury function score and less brain water content，and its cell pyknosis，edema，and other conditions significantly subsided. In the combined treatment group，the apoptosis level of hippocampal neurons decreased（ P<0.05）；the AQP4，p-JAK2，and p-STAT3 expressions decreased，while the BDNF expression increased（ P<0.05）. Conclusion:Hematoma aspiration combined with HBO therapy has a protective effect on rat brain with injury due to cerebral hemorrhage，and the protective mechanism may be related to the inhibition of JAK2/STAT3 signaling pathway．

Objective:To explore the protective effects of hematoma aspiration combined with hyperbaric oxygen（HBO）therapy on the brain tissue of rats after cerebral hemorrhage.Methods:A total of 40 rats were randomly divided into four groups：sham operation group，model group，operation group（hematoma aspiration），and combined treatment group（minimally invasive hematoma aspiration + HBO），with 10 rats in each group. The neurological deficits of rats in each group were scored by Longa scoring method. The water content of the brain tissue of rats in each group was detected by dry/wet weight measurement. The pathological changes in the hippocampus tissue of rats in each group were observed by H&E staining. The number of hippocampal neuronal apoptosis of rats in each group was detected by TUNEL assay. The expression levels of brain derived neurotrophic factor（BDNF）and Aquaporin-4（AQP4）in the hippocampus of rats in each group were detected by qRT-PCR and Western blotting. The protein expressions of Bax，Bcl-2，JAK2，p-JAK2，STAT3，and p-STAT3 in the brain tissue of rats in each group were detected by Western blotting.Results:Compared with the sham operation group，the model group had significantly higher nerve injury function scores and brain tissue water content，and showed brain tissue hemorrhage，cell pyknosis，enlarged intercellular space，increased glial cells，and decreased neurons；the apoptosis level of hippocampal neurons in the model group increased（ P<0.05）；the AQP4，p-JAK2，and p-STAT3 expressions in the model group increased，while the BDNF expression in the model group decreased（ P<0.05）. Compared with the model group，the operation group and the combined treatment group had lower nerve injury function scores and less brain tissue water content，and the brain tissue injury in the two groups was reduced. In both groups，the apoptosis level of hippocampal neurons decreased（ P<0.05）；the AQP4，p-JAK2，and p-STAT3 expressions decreased，while the BDNF expression increased（ P<0.05）. Compared with the operation group，the combined treatment group had significantly lower nerve injury function score and less brain water content，and its cell pyknosis，edema，and other conditions significantly subsided. In the combined treatment group，the apoptosis level of hippocampal neurons decreased（ P<0.05）；the AQP4，p-JAK2，and p-STAT3 expressions decreased，while the BDNF expression increased（ P<0.05）. Conclusion:Hematoma aspiration combined with HBO therapy has a protective effect on rat brain with injury due to cerebral hemorrhage，and the protective mechanism may be related to the inhibition of JAK2/STAT3 signaling pathway．

To assess the indication, intraoperative monitoring with selective shunting and surgical outcomes of carotid endarterectomy for patients with contralateral carotid occlusion, the clinical manifestations, imaging data, surgical methods and results of 16 patients were analysed retrospectively. It was verified that the surgical risk of these patients was not as high as prediction,satisfactory results coold be achieved with intraoperative monitoring, selective shunting and skilled surgical techniques. It is reasonable to offer the following typical treatment examples: Carotid endarterectomy should be performed for patients with symptomatic carotid stenosis irrespective of the contralateral carotid occlusion, while medical therapy should be maintained for patients with asymptomatic carotid stenosis and contralateral carotid occlusion. maintained. If the asymptomatic stenosis is found to be progressing in noninvasive testing, then a prophylactic endarterectomy should be considered.

Exposure of the distal internal carotid artery is very important and difficult in carotid endarterectomy for patients with high bifurcations or extension of the atherosclerotic plaque into the distal internal carotid artery. Exposure techniques are introduced based on the surgical experiences of 28 cases.