Objective:To explore the role cognition and learning experience of Traditional Chinese Medicine (TCM) nursing postgraduate students with professional degree in their freshman stage.Methods:Using the purposive sampling method, a total of 12 full-time grade-2023 TCM nursing postgraduate students with professional degree from School of Nursing in Hubei University of Chinese Medicine were selected as research objects for semi-structured in-depth interviews in 2024. Colaizzi analysis method was used to organize and analyze the interview results.Results:The role cognition of TCM nursing postgraduate students with professional degree in their freshman stage could be summarized into four themes, such as role motivation, role identity, role expectation and role gap. The learning experience of TCM postgraduate nursing students with professional degree in their freshman stage could be summarized into four themes, including the reunderstanding of TCM nursing specialty, the learning experience of TCM nursing theory, the learning experience of clinical practice and the training mode of TCM nursing postgraduate students with professional degree.Conclusions:The role cognition and learning experience of TCM nursing postgraduate students with professional degree in their freshman stage need to be improved. Nursing educators should take auxiliary and targeted measures to strengthen the role cognition education and learning guidance, fully understand the training experience and needs of nursing postgraduate students with professional degree in their freshman stage and identify the shortcomings of the training model from the perspective of educators and make targeted improvements, so as to better promote talent training.

China ; Humans ; Lenalidomide/therapeutic use* ; Multiple Myeloma/drug therapy* ; Thalidomide ; Therapeutic Equivalency

Objective: To explore the correlation among plasma level of brain natriuretic peptide (BNP), serum D-dimer level and patient's status in patients with acute pulmonary embolism (APE).Methods: A total of 122 APE patients who were hospitalized from Mar 2012 to Dec 2015 were selected.According to right heart function and clinical symptoms, patients were divided into low risk group (n=61), medium risk group (n=36) and high risk group (n=25);after discharge, all patients were followed up for six months, then according to survival or not, they were divided into survival group (n=105) and death group (n=17).Plasma BNP and serum D-dimer levels were measured and compared among all groups, then correlation among BNP, D-dimer levels and severity of patient's status was analyzed.Results: Compared with low risk group, there were significant rise in levels of plasma BNP [(133.28±74.92)ng/L vs.(273.89±179.29)ng/L vs.(834.80±509.09)ng/L] and serum D-dimer [(761.80±333.65)ng/ml vs.(966.67±370.33)ng/ml vs.(1228.40±569.11)ng/ml] in medium risk group and high risk group, and those of high risk group were significantly higher than that of medium risk group, P<0.01 all.Compared with survival group, there were significant rise in levels of plasma BNP [(257.33±27.11)ng/L vs.(696.47±64.92)ng/L] and serum D-dimer [(818.57±64.92)ng/ml vs.(1513.25±48.14)ng/ml] in death group, P<0.01 all.Pearson correlation analysis indicated that plasma BNP, serum D-dimer levels were significant positively correlated with severity of patient's status (r=0.69, 0.41, P<0.01 both), and plasma BNP level was significant positively correlated with serum D-dimer level (r=0.79, P=0.002).Conclusion: Measurements of plasma BNP and serum D-dimer in APE patients are help to assess severity of patient's status and short-term prognosis, and provide basis for clinical individualized therapy.

The differentiation of neural stem cells/neural precursors (NSCs/NPs) is a hot spot in neurobiological research. It used to identify their differentiation degree only by morphologic appearances. The functional characteristics, such as electrical properties of cellular membrane and ion channel activities, are drawing more and more attention with the development of patch clamp technique. It was summarized the recent progress in the study of NSCs/NPs functional differentiation using patch clamp, some existing problems and research perspectives were suggested.