This experiment was conducted to investigate the effects of agaric polysaccharides on an-tioxidant capacity,immune function,and intestinal flora of calves.Twenty-four healthy Holstein calves of(30±3)days of age and with the similar body weight at(55.33±1.86)kg were selected and randomly divided into two groups:the control group(group C)and test group(group T)with 12 replicates in each group and one calves in each replicate.Group C was fed starter and milk repla-cer,and group T was fed starter and milk replacer with 10 g of agaric polysaccharides to each calve for 10 d.Serum antioxidant,immune indexes and intestinal flora were tested.The results showed as follows:compared with group C,the enzyme activities of SOD and GSH-Px in serum of calves in group T were significantly increased(P＜0.05),and were increased by 29.09％and 15.35％,re-spectively;compared with group C,IgA,IL-2 and TNF-α were significantly increased in T group(P＜0.05).Adding agaric polysaccharides significantly increased the relative abundance of Firmi-cutes(P＜0.05)and decreased the relative abundance of Proteobacteria in feces of calf(P＞0.05);the relative abundance of Lactobalillus and Faecalibacterium were increased(P＜0.05);the relative abundance of Butyricoccus-pullicaecorum was increased(P＜0.05).LEfSe analysis results showed that there were 11 marker species in group T,such as Firmicutes and Lactobacillus,and 9 marker species in group C,such as Proteobacteria.The results showed that agaric polysaccharides could improve the antioxidant capacity and immune function of calves,and also could improve the structure of intestinal flora.

OBJECTIVE:To investigate the perioperative use of antibacterials in patients undergoing C-sect.METHODS:The medical records of 753 cases between Oct.2005 and Mar.2007 were reviewed retrospectively.RESULTS:All the patients(100.00%)undergoing C-sect received antibacterials by iv gtt during perioperative period,and 99.07% were given at 0.5h before operation.Among all the antibacterials,73.31% were benzylpenicillin sodium.86.85% of the patients had a course of treatment of 2～3 days;93.36% of the antibacterials were used in single kind.As for the preventive medication outcome,the effective rate totaled 99.20%(694 CR+ 53 PR).CONCLUSION:The perioperative use of antibacterials in patients undergoing C-sect was rational on the whole.The antibacteirals were more often used singly for a course of 2 to 3 days.The low grade kind with low toxicity and cheap price is the preferred preventive medication for patients undergoing C-sect.