1.Guidelines for the Digital Ancient Books of TCM Indexing
Weina ZHANG ; Bing LI ; Bin LI ; Jing XIE ; Yan DONG ; Wei LONG ; Chuchu ZHANG ; Tong WEI ; Sihong LIU ; Yang WU ; Hongtao LI ; Lin TONG ; Guangkun CHEN ; Fei DONG ; Rui WANG ; He LU ; Meng LI ; Jingpeng DENG ; Tengfei WANG ; Xiaoying LI ; Di ZHANG
Chinese Journal of Information on Traditional Chinese Medicine 2025;32(3):1-11
Guidelines for Digital Ancient Books of TCM Indexing(T/CIATCM 119-2024)is based on the theoretical knowledge,disciplinary methods,and practical applications of TCM classical cataloging.Taking digital ancient books of TCM as the object,it systematically reveals the content of TCM knowledge,which is an essential indexing processing standard for building an intelligent retrieval system for TCM ancient books,and can provide support for the deep development and innovative utilization of TCM knowledge.It can not only promote the co-construction and sharing of ancient book resources in the TCM industry,but also promote the standardization construction and application of TCM information.This standard specifies the principles,methods,and examples of free indexing of digital ancient books of TCM based on their original content.It is applicable to the indexing and processing of digital ancient books of TCM for TCM professional libraries and related institutions,and to the data processing and construction of various types of TCM ancient book databases.
2.Guidelines for the Digital Ancient Books of TCM Indexing
Weina ZHANG ; Bing LI ; Bin LI ; Jing XIE ; Yan DONG ; Wei LONG ; Chuchu ZHANG ; Tong WEI ; Sihong LIU ; Yang WU ; Hongtao LI ; Lin TONG ; Guangkun CHEN ; Fei DONG ; Rui WANG ; He LU ; Meng LI ; Jingpeng DENG ; Tengfei WANG ; Xiaoying LI ; Di ZHANG
Chinese Journal of Information on Traditional Chinese Medicine 2025;32(3):1-11
Guidelines for Digital Ancient Books of TCM Indexing(T/CIATCM 119-2024)is based on the theoretical knowledge,disciplinary methods,and practical applications of TCM classical cataloging.Taking digital ancient books of TCM as the object,it systematically reveals the content of TCM knowledge,which is an essential indexing processing standard for building an intelligent retrieval system for TCM ancient books,and can provide support for the deep development and innovative utilization of TCM knowledge.It can not only promote the co-construction and sharing of ancient book resources in the TCM industry,but also promote the standardization construction and application of TCM information.This standard specifies the principles,methods,and examples of free indexing of digital ancient books of TCM based on their original content.It is applicable to the indexing and processing of digital ancient books of TCM for TCM professional libraries and related institutions,and to the data processing and construction of various types of TCM ancient book databases.
3.Optimization the Fresh Processing Method of Puerarial Lobatae Radix Based on Entropy Weight TOPSIS Model and Multi-index Evaluation
Tao WANG ; Xiaoying DING ; Hengyang LI ; Long GUO ; Yuguang ZHENG ; Dan ZHANG
Chinese Journal of Modern Applied Pharmacy 2024;41(1):9-17
OBJECTIVE
To evaluate the effects of different fresh processing methods on the quality of Puerarial Lobatae Radix using entropy weight TOPSIS model and multi-index.
METHODS
By optimizing the specifications of fresh cut(thick slices of 2, 3, 4 mm thick, the side length of 0.5, 1, 1.5 cm), drying method(drying at 45, 65, 85 ℃, freeze drying) and other parameters, Puerarial Lobatae Radix medicinal materials were processed at the origin, and Puerarial Lobatae Radix decoction pieces were obtained. Using the content of 3′-hydroxy puerarin, puerarin, puerarin apioside, 3′-methoxy puerarin, puerarin-6″-O-xyliside, daidzin, genistin, daidzein, ethanol soluble extractives, as well as moisture and ash content limits as evaluation indicators, through the entropy and TOPSIS method to analyze the index component data and optimizing the Puerarial Lobatae Radix best when fresh herbs processing technology.
RESULTS
Different fresh processing methods had a certain influence on the content of the index components of Puerarial Lobatae Radix, and the best cutting specification was 0.5 cm thick, and the best drying method was freezed drying.
CONCLUSION
The entropy weight TOPSIS method can be used to evaluate the effects of different processing methods on the quality of Puerarial Lobatae Radix, and the best processing technology obtained has good stability and repeatability, which can provide guidance for the standardization of processing technology of Puerarial Lobatae Radix.
4.Research progress on moral resilience of medical staff
Tong WANG ; Xiaoying WANG ; Long CUI ; Yunli CHANG ; Xiaoming ZHOU
Chinese Medical Ethics 2024;37(2):224-228
To review the concept development,characteristics,measurement tools,influencing factors,effects,and cultivation of moral resilience among medical staff at home and abroad.The characteristics of moral resilience of medical staff include personal integrity,adaptability,self-regulation,self-management,and moral efficacy of medical personnel,as well as the relational integrity of the medical team.The influencing factors of medical staff's moral resilience include the support system of the medical team,personal qualities of medical staff,and their understanding of events.Moral resilience can promote the physical and mental health of medical staff,effectively cope with moral injury,reduce occupational fatigue and turnover intention of medical staff,as well as alleviate the moral dilemmas of medical staff.Cultivate moral resilience to enhance the ability of medical staff to resist moral dilemmas.
5.Neoadjuvant sintilimab and apatinib combined with perioperative FLOT chemotherapy for locally advanced gastric cancer: A prospective, single-arm, phase II study.
Huinian ZHOU ; Bo LONG ; Zeyuan YU ; Junmin ZHU ; Hanteng YANG ; Changjiang LUO ; Wenjuan ZHANG ; Chi DONG ; Xiaoying GUAN ; Long LI ; Gengyuan ZHANG ; Hongtai CAO ; Shigong CHEN ; Linyan ZHOU ; Qichen HE ; Shiying GAN ; Xiangyan JIANG ; Qianlin GU ; Keshen WANG ; Wengui SHI ; Long QIN ; Zuoyi JIAO
Chinese Medical Journal 2024;137(21):2615-2617
6.Comprehensive Evaluation of Health Status of Traditional Chinese Medicine Constitution based on Improved Radar Chart
Xinyuan ZHAO ; Yanbo ZHU ; Jianni CONG ; Liqun LONG ; Xiaoying LYU ; Qian ZHANG
Journal of Traditional Chinese Medicine 2023;64(19):2003-2009
ObjectiveTo present the health status of traditional Chinese medicine (TCM) constitutions more intuitively and comprehensively based on improved radar chart. MethodsParticipants who completed a 26-week comprehensive intervention based on TCM constitution from February 2013 to January 2014 in Zhuhai branch of Guangdong Provincial Hospital of Chinese Medicine were included in the study. They were divided into groups according to gender and age, i.e. young, middle-aged, and elderly male and female groups. TCM constitution scale and health survey short form (SF-36) were used to evaluate the 9 basic TCM constitution types and quality of life at three time points, including pre-intervention (T1), at 13-week intervention (T2), and at 26-week intervention (T3). The improved radar charts were drawn to visually present the comprehensive evaluation results on the health status of 9 TCM constitutions, and graphic features (area S value, perimeter L value) were extracted to construct a comprehensive health index for TCM constitutions (H value). Spearman correlation analysis was used to analyze the correlation between H value and SF-36 total score. ResultsAmong the included 509 participants, there were 45 elderly male, 76 elderly female, 60 middle-aged male, 140 middle-aged female, 53 young male and 135 young female. The radar charts for comprehensive evaluation of TCM constitution health status showed that the total areas for all groups increased at T3 compared to T1, with the most significant increase in the young population. In the middle-aged population, the fan-shaped areas of certain constitutions decreased at T2 than T1. At T3, the radar chart shapes for females were more balanced than males in the same age group. By calculating the features of function graphs, it was found that the S, L, and H values for the elderly population were relatively higher than those for the middle-aged and young population with the same gender, and the young population increased by highest ratio. The values measured at T3 compared to T1 showed average increase of 26% for S value (11% for the middle-aged and 14% for the elderly), 22% for L value (10% for the middle-aged and the elderly each), and 22% for H value (10% for the middle-aged and 9% for the elderly). The female had lower S and L values, as well as higher H value than the male of the same age group measured at T3. The correlation coefficient between the H value of all participants and the total SF-36 score was 0.662 (P<0.01). ConclusionThe comprehensive evaluation model for the health status of TCM constitution based on the improved radar chart constructed in this study can present the health status of TCM constitutions and intervention effectiveness more comprehensively and intuitively. It is suggested to regulate the constitution in pursuit of the dynamic balance of the constitution health status, as well as consider the parts from the whole, and put focus on the balance of nine TCM constitutions.
7.Effects of hyperbaric oxygen therapy at different time windows after optic nerve injury in rats by F-VEP
Bing LONG ; Liqiong ZHOU ; Dan YAN ; Shengping LUO ; Xu ZHA ; Xia CAO ; Zhang LI ; Xiaoying SUN ; Ji LI ; Yuanping ZHANG
Chinese journal of nautical medicine and hyperbaric medicine 2019;26(2):108-111,115
Objective To observe flash visual evoked potential (F-VEP)after hyperbaric oxygen (HBO) at different time points after traumatic optic nerve injury (TON) in adult rats,so as to explore the optimal time window for HBO therapy.Methods A total of 40 Sprague-Dawley rats were used to establish an optic nerve contusion model,with the left eye as the optic nerve injury eye and the right eye as the sham surgery control eye.In accordance with different HBO intervention time points of the optic nerve contusion model at 1,3,7 and 14 days,and the animals were divided into 5 groups,i.e.the experimental group 1,group 2,group 3,group 4 and the control group,each consisting of 8 rats.In the course of treatment,F-VEP visual changes in the 5 groups were detected at day 3,day 10 and day 20,and therapeutic effects were evaluated.Results When the detected VEP data of the optic nerve-clamped eye in all the control rats were compared with those of the sham surgical eyes,latent time was prolonged and vibration amplitude was obviously decreased,and statistical significance could be found,when comparisons were made between them (P < 0.05).Compared with the F-VEP data of the control group,latent time of the optic nerve-clamped eye in the experimental group 1 at various time points was considerably shortened,and at day 10 and day 20 after treatment,vibration amplitude was significantly increased,all with statistical significance (P < 0.05).However,latent time of the optic nerve-clamped eye in the experimental group 2 at day 10 and day 20 after treatment was obviously shortened,also with statistical significance (P < 0.05),but no statistical significance could be noted in vibration amplitude,when comparisons were made between them (P > 0.05).When compared with the F-VEP data of the control group,no statistical significance could be found in the changes of latent time and vibration amplitude for the experimental group 3 and group 4 (P > 0.05).Conclusion Early HBO treatment could effectively improve F-VEP of the rats with traumatic optic nerve contusion,and after sustainment of optic nerve injury,the early the HBO intervention,the better therapeutic effects would be achieved.
8.Effects of hyperbaric oxygen therapy at different time windows after optic nerve injury in rats by F-VEP
Bing LONG ; Liqiong ZHOU ; Dan YAN ; Shengping LUO ; Xu ZHA ; Xia CAO ; Zhang LI ; Xiaoying SUN ; Ji LI ; Yuanping ZHANG
Chinese journal of nautical medicine and hyperbaric medicine 2019;26(2):108-111,115
Objective To observe flash visual evoked potential (F-VEP)after hyperbaric oxygen (HBO) at different time points after traumatic optic nerve injury (TON) in adult rats,so as to explore the optimal time window for HBO therapy.Methods A total of 40 Sprague-Dawley rats were used to establish an optic nerve contusion model,with the left eye as the optic nerve injury eye and the right eye as the sham surgery control eye.In accordance with different HBO intervention time points of the optic nerve contusion model at 1,3,7 and 14 days,and the animals were divided into 5 groups,i.e.the experimental group 1,group 2,group 3,group 4 and the control group,each consisting of 8 rats.In the course of treatment,F-VEP visual changes in the 5 groups were detected at day 3,day 10 and day 20,and therapeutic effects were evaluated.Results When the detected VEP data of the optic nerve-clamped eye in all the control rats were compared with those of the sham surgical eyes,latent time was prolonged and vibration amplitude was obviously decreased,and statistical significance could be found,when comparisons were made between them (P < 0.05).Compared with the F-VEP data of the control group,latent time of the optic nerve-clamped eye in the experimental group 1 at various time points was considerably shortened,and at day 10 and day 20 after treatment,vibration amplitude was significantly increased,all with statistical significance (P < 0.05).However,latent time of the optic nerve-clamped eye in the experimental group 2 at day 10 and day 20 after treatment was obviously shortened,also with statistical significance (P < 0.05),but no statistical significance could be noted in vibration amplitude,when comparisons were made between them (P > 0.05).When compared with the F-VEP data of the control group,no statistical significance could be found in the changes of latent time and vibration amplitude for the experimental group 3 and group 4 (P > 0.05).Conclusion Early HBO treatment could effectively improve F-VEP of the rats with traumatic optic nerve contusion,and after sustainment of optic nerve injury,the early the HBO intervention,the better therapeutic effects would be achieved.
9.Research progress on in vitro lipolysis model for the evaluation of lipid formula-tions
Journal of Pharmaceutical Practice 2017;35(6):481-484,489
In vitro lipolysis model has become a new and promising technique to screen and evaluate oral lipid formula-tions .This model mimics the gastrointestinal tract environment and well reflects the fate of lipid formulations in GI tract after oral administration .This review summarizes the characteristics of lipid formulations ,process of gastrointestinal digestion ,ap-plications of in vitro lipolysis model and methods for the characterization of the lipolysis process ,which provides the basis for the research of oral absorption mechanism and in vivo-in vitro correlations of lipid formulations with lipolysis model .
10.Clinical study of emerging sternal rigid plate:a randomized controlled double-center trial
Bin WANG ; Dapu HE ; Yongxiang QIAN ; Bing WEI ; Dongmei DI ; Yaoguang FENG ; Xianghong ZHAN ; Chaozhong LONG ; Rui ZHOU ; Xiaoying LIANG ; Zhang MO
Chinese Journal of Thoracic and Cardiovascular Surgery 2017;33(12):743-746
Objective To evaluate the security and effectiveness of emerging sternal rigid plate by comparing with wires closure. Methods 60 patients who undergoing median sternotomy from two centers were enrolled in this study, 30 received wire cerclage( control group) and the other 30 received rigid plate fixation( experimental group) . Patients' sternal were closed with wires or rigid plates, and the painness, sternal union and status of wires or rigid plates were followed up and assessed one week, three months and six months after procedures. Results All patients survived and were followed up. 117 rigid plates were implanted. There was no significant difference in pre-operative data, post-operative painness, sternal union and status of wires and plates between control and experimental group. No patient reached the standard of clinical sternal union one week post-operation, but all patients reached the standard of clinical sternal six months post-operation. One patient in control group suffered sternal nonunion, movement and wound infection after sternotomy. Conclusion Compared to wire closure, sternal closure with rigid plates is the same safe and effective.


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